B—ISDN宽带UNI信令点到多点配置的实现

本文根据ＩＴＵ－Ｔ最新的Ｑ．２９７１协议，以及笔者所从事的实际课题，提出一整套Ｂ－ＩＳＤＮ第三层ＵＮＩ信令的软件实现策略，其特点是能同时满足用户对点到点以及点到多点广播这两种通信方式的要求，而且可以动态配置。     

The percutaneous endoscopic treatment of staghorn nephrolithiasis

Hyperferremia is shown to affect antioxidant system of the body, oxidation-reduction reactions in the cells seen as shifts in lymphocyte chemiluminescence. Dynamic changes in lymphocyte chemiluminescence reflect the level of hyperferremia.     

The significance of spinal cord compression as the initial manifestation of lymphoma

Sex hormones have profound effects on immune responses and may influence the outcome of autoimmune diseases such as rheumatoid arthritis (RA). We investigated the effect of gonadal steroids on the production of interleukin-1 (IL-1) and IL-6, cytokines believed to be important in the pathogenesis of RA. Peripheral blood mononuclear cells (PBMCs) were isolated from healthy male donors and male patients with RA, and were stimulated with lipopolysaccharide (LPS) in the presence of different concentrations of 17-beta-estradiol, progesterone or testosterone. In studies of cells from normal male donors, 17-beta-estradiol at pharmacological concentrations (> or = 10(-6) M) enhanced IL-1 and IL-6 secretion as well as the production of cell-associated IL-1. Progesterone and testosterone at similar concentrations inhibited IL-1 secretion but had no significant effect on IL-6 secretion or on the production of cell-associated IL-1. In studies of male RA donors, 17-beta-estradiol failed to enhance IL-1 or IL-6 secretion and progesterone failed to inhibit IL-1 secretion. The inhibitory effects of testosterone, however, appeared to be similar to that in normal donors. It is suggested that 17-beta-estradiol may promote IL-1 and IL-6 production and release, while gestation hormone, progesterone, and testosterone may inhibit IL-1 release in vivo. These data may partly explain the gender and age differences in the incidence of RA and the development of the disease in men with low and androgen levels.     

Results of initial surgery and adjuvant chemotherapy in treating small-cell lung cancer

The changes in the intestinal mucosal permeability were observed by quantitatively assessing plasma to luminal clearance of 99mTc-labeled DTPA, and the influence of platelet activating factor (PAF) on it was investigated. The results showed that intestinal permeability was significantly elevated after severe burn and was positively correlated with increase in PAF in the intestinal tissue (r = 0.94, P < 0.01). PAF antagonist therapy could significantly attenuate postburn intestinal mucosal permeability. It is concluded that PAF is one of the important factors causing increased intestinal permeability after severe burn.     

Analysis of a 2(9) full factorial chemical library

Robotic synthesis is making possible the synthesis of large, systematically designed sets of compounds. We analyze a 512-compound set that is a 2(9) full factorial experimental design using a recursive partitioning algorithm, FIRM, and a high-dimension visualization tool, TempleMVV. These techniques are used to quickly and easily identify the main trends in the data set and also identify unusual observations. We show that analytical and visualization methods can be used synergistically to analyze a large, complex, high-dimensional data set. We also show that a fractional factorial design of 128 compounds would give essentially the same information.     

CaF_2-CaO-MgO-Al_2O_3-SiO_2电渣渣系高温力学性能的研究

本文针对结晶器与铸锭作相对移动的电渣重熔过程中对渣系的高温强度及塑性的要求,对10种CaF_2-CaO-MgO-Al_2O_3-SiO_2渣组成进行了渣的高温强度及塑性的测定,建立了渣组成—渣的岩相结构—渣高温强度及塑性间的对应关系,并选择出较合适的成分范围为CaF_2 35～60％,CaO 10～25％,Al_2O_3 10～20％,SiO_25～15％,MgO≈5％。对其中一个成分的渣进行了电渣热穿孔熔铸中空锭生产实验,并取得了良好的表面质量。     

NUMERICAL SIMULATION OF STREAMBED HEAT TRANSFER

１．　ＩＮＴＲＯＤＵＣＴＩＯＮＴｈｅｓｉｍｕｌａｔｉｏｎｏｆｓｔｒｅａｍｗａｔｅｒｔｅｍｐｅｒａｔｕｒｅｉｓｓｉｇｎｉｆｉｃａｎｔｌｙｉｍｐｏｒｔａｎｔｆｏｒｔｈｅｓｔｕｄｙｏｆｎｕｍｅｒｉｃａｌｍｏｄｅｌｉｎｇｏｆｒｉｖｅｒｉｃｅｐｒｏｃｅｓｓｅｓ［１］　．Ｈｉｓｔｏｒｉｃａｌｌｙ，ｔｈｅｍａｔｈｅｍａｔｉｃａｌｍｏｄｅｌｉｎｇｏｆｔｈｅｔｒａｎｓｐｏｒｔａｎｄｆａｔｅｏｆｈｅａｔｉｎａｗａｔｅｒｂｏｄｙｈａｓｂｅｅｎｔｈｅｓｕｂｊｅｃｔｏｆｅｘｔｅｎｓｉｖｅｓｔｕｄｙｆｏｒｖａｒｉｏｕｓｒｅ…     

In vitro and in vivo studies on the cardioprotective action of oligomeric procyanidins in a Crataegus extract of leaves and blooms

Cardioprotective effects of a standardized extract from leaves with flowers of Crataegus (WS-1442; content of oligomeric procyandins [OPC]: 18.75%) have recently been demonstrated in an ischemia-reperfusion model in rats. Further studies were now conducted to clarify the mechanism of action and to identify active constituents involved in these effects of WS-1442. Exhausting partitioning between ethyl acetate/water and successive ultrafiltration of the aqueous layer led to the quantitative recovery of three fractions, which were tested for their in vitro radical scavenging (RS) and human neutrophil elastase (HNE) inhibitory activity. The lipophilic ethylacetate-soluble fraction A, enriched in flavone derivatives and constituting 14.9% of WS-1442, was as active as WS-1442 in inhibiting HNE. However, its RS activity was only about half that of the primary extract. Although 67.9% of WS-1442 was recovered in a water-soluble low molecular weight fraction B, this fraction displayed only weak RS and HNE inhibiting activity. In contrast, the RS and HNE inhibiting potencies of an essentially flavone-free and OPC-rich fraction C (21.3% of WS-1442) were significantly higher (inhibition of lipid peroxidation: IC50 0.3 microgram/ml; inhibition of HNE: IC50 0.84 microgram/ml) as those of WS-1442. The RS and HNE inhibitory activities of the extract and those of its fractions correlated well with their OPC-content but not with their concentration of flavonols. These results demonstrate that OPCs of Crataegus extracts possess stronger radical scavenging activities than flavone derivatives or other constituents. In addition, the oligomeric components are potent inhibitors of HNE. Oral administration of 20 mg/kg/d of the OPC-rich fraction C to rats afforded similar protection against ischemia-reperfusion induced pathologies as treatment with WS-1442 at a dose of 100 mg/kg/d. These observations indicate that radical scavenging and elastase inhibitory activities could indeed be involved in the observed cardioprotective effects of WS-1442, and demonstrate that OPCs are major orally active constituents of WS-1442. Thus, Crataegus extracts used therapeutically for cardiovascular diseases should be analyzed and standardized for their OPC-content.     

节流式差压流量计的发展和现状

文章介绍节流式差压流量计的特点及标准化进程，煤气流量测量中存在的难点以及正在试图解决的途径。