Extraction optimisation,antioxidant activity and inhibition on α-amylase and pancreatic lipase of polyphenols from the seeds of Syzygium cumini

The objectives of this study were to determine the optimal extraction conditions of polyphenols from Syzygium cumini seeds by response surface methodology and investigate their antioxidant activity and inhibition on α-amylase and pancreatic lipase. As results, the optimal extraction conditions in the ultrasonic extraction process which maximised total polyphenols content, minimised the IC₅₀ values of α-amylase and pancreatic lipase were determined as follows: extraction time 60 min, ethanol concentration 63% and solvent/solid ratio 44 mL g⁻¹. The main phenolic compounds in partially purified fraction of Syzygium cumini seeds were catechin, epicatechin, kaempferol, gallic, 5-caffeoylquinic, caffeic and ferulic acids. In addition, the partially purified fraction inhibited 87.66 ± 5.55 and 86.61 ± 3.15% of α-amylase and pancreatic lipase, respectively. The results suggested that Syzygium cumini seeds could be explored as a natural antioxidant and could be used as a source of highly antidiabetic and anti-obesity bioactive compounds.     

Groundwater potential modelling in a soft rock area using a GIS

A Geographical Information System (GIS) integration tool is proposed to demarcate the groundwater potential zone in a soft rock area using seven hydrogeologic themes: lithology, geomorphology, soil, net recharge, drainage density, slope and surface water bodies. Except for net recharge and slope, the other five themes are derived from remote sensing data. IRS-1B LISS-II data was used for a 631 km² area in Midnapur District, West Bengal, India. While slope was calculated using topographic sheets, net recharge was obtained from annual water table fluctuation data. Each feature of all the thematic maps was evaluated according to its relative importance in the prediction of groundwater potential. The evolved GIS-based model of the study area was found to be in strong agreement with available borehole and pumping test data.     

Probiotics for cure of Helicobacter pylori infection: A review

Human physiology normally contains pathogenic and non-pathogenic microorganisms in the gastrointestinal flora. Disturbance of these microorganism balance results in the formation of infection. Extensive use of antibiotics for cure of these disturbances like Helicobacter pylori (H. pylori) infection leads to patient discomfort and associated side-effects. There is a need to adopt adjunct or alternative approach in order to minimize such conditions. Probiotics is one of the potential therapies to cure gastrointestinal discomforts especially associated with H. pylori. It competes through non-immune and immune systems. This review article concludes that probiotics are used to eradicate the infection at increased rate, and decreased associated side-effects are caused by triple therapy. A proper evaluation of these probiotics is demanded before their use in future as a commercial product. Furthermore, their effect on immune system requires more research work so that their usage for other chronic disorders can also be considered.     

Zero-current Switching Series Resonant High-voltage DC-DC Converter with Series-connected Primary Windings of Center-tapped Transformer

Abstract—This article proposes a novel zero-current switching series resonant inverter-fed voltage multiplier based high-voltage DC-DC converter. The series resonant inverter in the proposed topology has two power switches (insulated-gate bipolar transistors), two resonant capacitors, and only one high-voltage transformer with center-tapped primary windings. The power switches are connected in the form of a half-bridge network. The leakage inductances of the transformer's primary windings together with resonant capacitors form two series resonant circuits. The series resonant circuits are fed alternately by operating power switches with an interleaved half-switching cycle. The secondary winding of the high-voltage transformer is connected to a voltage multiplier circuit to rectify and boost the voltage. The converter operates in discontinuous conduction mode, and its output voltage is regulated by pulse-frequency modulation. Therefore, all the power switches turn ON and OFF at the zero-current switching condition. The main features of the proposed converter are lower power loss, less cost, and smaller size compared to previously proposed series resonant high-voltage DC-DC converters. The experimental results of a 130-W prototype of the proposed converter are presented both for dynamic and steady-state operation. The results confirm the excellent operation and performance of the converter.     

Synthesis and Properties of MoSi2–MoB–SiC Ceramics

MoB and SiC particulate reinforced MoSi₂ matrix composites were synthesized in situ from Mo, Si, and B₄C powder mixtures by self‐propagating high‐temperature synthesis (SHS). The SHS MoSi₂–MoB–SiC products were vacuum hot‐pressed (HPed) at 1400°C for 90 min to fabricate high‐density (> 97.5% relative density) bulk composites. Microstructure refinement and improvements in the Vickers hardness and fracture toughness of the HPed composites were observed with increasing B₄C content in the reaction mixture. The HPed composite of composition MoSi₂–0.4MoB–0.1SiC exhibited grain size of 1–5 μm, Vickers hardness of 12.5 GPa, bending strength of 537 MPa, and fracture toughness of 3.8 MPa.m^1/2. These excellent mechanical properties indicate that MoB and SiC particulate reinforced MoSi₂ composites could be promising candidates for structural applications.     

Platinum on nitrogen doped graphene and tungsten carbide supports for ammonia electro-oxidation reaction

Ammonia electrooxidation reaction involving multistep electron-proton transfer is a significant reaction for fuel cells, hydrogen production and understanding nitrogen cycle. Platinum has been established as the best electrocatalyst for ammonia oxidation in aqueous alkaline media. In this study, Pt/nitrogen-doped graphene (NDG) and Pt/tungsten monocarbide (WC)/NDG are synthesized by a wet chemistry method and their ammonia oxidation activities are compared to commercial Pt/C. Pt/NDG exhibits a specific activity of 0.472 mA∙cm^–2, which is 44% higher than commercial Pt/C, thus establishing NDG as a more effective support than carbon black. Moreover, it is demonstrated that WC as a support also impacts the activity with further 30% increase in comparison to NDG. Surface modification with Ir resulted in the best electrocatalytic activity with Pt-Ir/WC/NDG having almost thrice the current density of commercial Pt/C. This work adds insights regarding the role of NDG and WC as efficient supports along with significant impact of Ir surface modification.     

Structural,viscoelastic, and vulcanization study of sponge ethylene–propylene–diene monomer composites with various carbon black loadings

In this article, we report the effect of various carbon nanoparticle concentrations on the structural, curing, tan δ, viscosity variation during vulcanization, thermal, and mechanical characteristics of ethylene–propylene–diene monomer polymer sponge composites. The purpose of this study was to develop high‐strength, foamy‐structure polymer composites with an optimum filler to matrix ratio for advanced engineering applications. We observed that the structural, vulcanization, viscoelastic, and mechanical properties of the fabricated composites were efficiently influenced with the progressive addition of carbon content in the rubber matrix. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131, 39423.