Closed-loop stability analysis of a gantry crane with heavy chain and payload

In this paper, we analyse a systematically designed and easily tunable backstepping-based boundary control concept for a gantry crane with heavy chain and payload. The corresponding closed-loop system is formulated as an abstract evolution equation in an appropriate Hilbert space. Non-restrictive conditions for the controller coefficients are derived, under which the solutions are described by a C₀-semi-group of contractions, and are asymptotically stable. Moreover, by applying Huang's theorem we can finally even show that under these conditions the controller renders the closed-loop system exponentially stable.     

pH and heat-induced structural changes of bovine apo-α-lactalbumin

The effects of pH and thermal treatments on conformation and association state of Ca²⁺-depleted bovine α-lactalbumin (apo-α-LA) have been studied by fluorescence spectroscopy, and molecular modelling. The experimental results demonstrate a third-state model for heat-induced unfolding of apo-α-LA, at pH 2.0, and an all-or-none transition of apo-α-LA, at pH 4.5 and 7.0, respectively. The heat-induced changes in the secondary and tertiary structure of α-LA were outlined after running molecular dynamics simulations at 25 °C and 80 °C, at neutral pH, therefore supporting the experimental observations. Our data provides insight into the mechanism of pH- and heat-dependent structural changes and oligomerization of α-LA, and will be helpful in understanding the ability of this protein to interact with certain compounds of biological interest.     

Artificial compliance inherent to the intrinsic cohesive zone models: criteria and application to planar meshes

In this study, criteria on the artificial compliance due to intrinsic cohesive zone models are presented. The approach is based on a micromechanical model for a collection of cohesive zone models embedded between each mesh of a finite element-type discretization. The overall elastic behaviour of this cohesive volumetric medium is obtained using homogenization techniques and is given in a closed-form as function of bulk properties of the relevant material and mesh parameters (the mesh type and size). Practical criteria are obtained for the calibration of the cohesive stiffnesses bounding the additional compliance inherent to intrinsic cohesive zone models by lower value. For isotropic planar discretizations (e.g. Delaunay mesh), a rigorous bound is derived whereas convenient estimates are given for non-isotropic discretizations (e.g. regular mesh).     

Towards a Theoretical Understanding of the Recurrence of Crises Embracing the Issue of Organizational Learning: An Illustration with the Case of Two Hostile Takeover Bids Faced by Société Générale (1988, 1999)

In this article, we try to better understand the relationship between learning and crisis through the analysis of recurrent crises. Our study focused on two successive and similar crises experienced by the same organization, namely two hostile takeover bids a French bank (Société Générale) had to cope with in 1988 and 1999. From a literature review within the fields of organizational learning and management crisis, we proposed an analytical grid making it possible to get a better understanding of crisis‐induced lesson‐drawing processes. We then used that grid to analyse and compare the learning processes implemented during the two crises under study. This comparison leads us to suggest that lack of organizational learning is one factor that accounts for crisis recurrence. Conversely, proactive crisis management behaviour – resulting from double‐loop learning – seems to be the most fruitful behaviour to adopt in order to prevent a recurrent crisis and produce long‐term effects in the organization.     

On the sensitivity of reactive tabu search to its meta-parameters

In this paper, we assess the sensitivity of reactive tabu search to its meta-parameters. Based on a thorough experimental analysis of reactive tabu search applications to the quadratic assignment and the maximum clique problem, we show that its performance is relatively insensitive to its meta-parameters. This is particularly evident when compared to the sensitivity of tabu search to its parameters: tabu search is rather penalized if used with sub-optimal parameter settings. Reactive tabu search does not strongly pay its high parameter robustness in terms of performance, although it does not improve the peak performance of tabu search.     

Droplet formation by squeezing in a microfluidic cross-junction

In microfluidics, flow focusing is widely used to produce water-in-oil droplets in microchannels at high frequency. We here report an experimental study of droplet formation in a microfluidic cross-junction with a minimum number of geometrical parameters. We mostly focus on the squeezing regime, which is composed of two distinct steps: filling and pinching. The duration of each step (and corresponding volumes of each liquid phase) is analyzed. They vary according to both water and oil flow rates. These variations provide several insights about the fluid flows in both phases. We propose several scaling laws to relate the droplet volume and frequency to the flow rate of both phases. We also discuss the influence of surfactant and channel compliance on droplet formation.     

Using immersive virtual reality and anatomically correct computer-generated characters in the forensic assessment of deviant sexual preferences

Penile plethysmography (PPG) is the gold standard for the assessment of sexual interests, especially among sex offenders of children. Nonetheless, this method faces some ethical limitations inherent to the nature of its stimuli and could benefit from the improvement of its ecological validity. The use of computer-generated characters (CGC) in virtual immersion for PPG assessment might help address these issues. A new application developed to design made-to-measure anatomically correct virtual characters compatible with the Tanner developmental stages is presented. The main purpose of this study was to determine how the virtual reality (VR) modality compares to the standard auditory modality on their capacity to generate sexual arousal profiles and deviance differentials indicative of sexual interests. The erectile responses of 22 sex offenders of children and 42 non-deviant adult males were recorded. While both stimulus modalities generated significantly different genital arousal profiles for sex offenders of children and non-deviant males, deviance differentials calculated from the VR modality allowed for significantly higher classification accuracy. Performing receiver operating characteristic analyses further assessed discriminant potential. Auditory modality yielded an area under the curve (AUC) of 0.79 (SE = 0.059) while CGC in VR yielded an AUC of 0.90 (SE = 0.052). Overall, results suggest that the VR modality allows significantly better group classification accuracy and discriminant validity than audio stimuli, which provide empirical support for the use of this new method for PPG assessment. Additionally, the potential use of VR in interventions pertaining to self-regulation of sexual offending is addressed in conclusion.