Feral travel and the transport field: Some observations on the politics of regulating skating in Tasmania

This paper summarises skating regulation around Australia, focusing on Tasmania. Such analysis is timely; the Australian Road Rules adopted in December 1999 expand skating from recreation to a mode of transport whose legitimacy assumes access to roads and footpaths, and deploys complex politics of identity and space, citizenship and access, and mobility.     

Fire resistance certification of aircraft composite materials

The Federal Aviation Administration (FAA) requires fire resistance certification of aircraft composite materials used in civil aircraft exterior structure and engine compartments. This paper presents an FAA approved process for accomplishing certification testing at minimum cost and time using an oxygen-acetylene heating tip. The test stand and process minimized human factors and quantified backside flame visibility for comparing aluminum and composite materials. The process focus was on demonstratingfire resistant characteristics, but could also be applied to thefireproof test process. Backside flame visibility was defined as the visual observance of light from the oxygen-acetylene flame. This definition was uniformly applied to both the aluminum test panels and the composite test panels. This presentation of the fire resistant certification process for aircraft composite materials will enable others to efficiently set up and perform both fire resistant and fireproof certification testing.     

Enclaves of Expression: Resistance by Young Architects to the Physical and Psychological Control of Expression in Romania during the 1980s

The eighties and early nineties bore witness to the gradual conclusion of a number of political regimes. This paper explores the work of various young Romanian architects and groups who, from the early eighties onwards, questioned current orthodoxies in architecture around them as protests against repression under the monolithic Ceausescu regime. It offers a glimpse, a fragment, of the wider "milieu of resistance" in Romania at this time, and reflects on the intention and value of such liminal enterprises through tracing their stories both from before the 1989 revolution and after.     

Shear Strengthening Masonry Panels with Sheet Glass-Fiber Reinforced Polymer

This paper investigates strengthening masonry walls using glass-fiber reinforced polymer (GFRP) sheets. An experimental research program was undertaken. Both clay and concrete brick specimens were tested, with and without GFRP strengthening. Single-sided strengthening was considered, as it is often not practicable to apply the reinforcement to both sides of a wall. Static tests were carried out on six masonry panels, under a combination of vertical preload, and in-plane horizontal shear loading. The mechanisms by which load was carried were observed, varying from the initial, uncracked state, to the final, fully cracked state. The results demonstrate that a significant increase of the in-plane shear capacity of masonry can be achieved by bonding GFRP sheets to the surface of masonry walls. The experimental data were used to assess the effectiveness of the GFRP strengthening, and suggestions are made to allow the test results to be used in the design of sheet GFRP strengthening for masonry structures.     

Yeast flocculation: Cationic inhibition

Yeast flocculation was inhibited by high concentrations of a number of salts. Calcium and magnesiun salts were potent inhibitors and cesium salts were least effective. Partial inhibitors by different salts additive and were completely reversible by salt removal. Inhibition by salts was time dependent; prolonged incubation increased the degree of inhibition. Salt inhibition was partly caused by the action of salts lowering the buffer pH value, and partly caused by chaotropic inhibition of proteins on the surfaces of flocculent cells. Flocculation receptors on non-flocculent cells were ubaffected by high salt concentration. At sub-inhibitory salt concentrations, there was an enhancement of flocculation in both rate and extent.     

一氧化氮对肿瘤细胞辐射敏感性的影响研究

调节肿瘤细胞中一氧化氮（Nitrogen monoxide,NO）的合成量,观察NO对细胞辐射敏感性的影响。结果显示乏氧和L-甲基盐酸精氨酸（L-N^G-Monomethylarginine hydrochloride,L-NMMA）作用均可显著抑制NO的合成,但对一氧化氮合酶（Inducible nitrogen monoxide synthase,iNOS）活性无显著影响;NO可以增强肿瘤细胞对射线的敏感性也增强,但两者变化并非线性相关;乏氧和L-NMMA作用抑制肿瘤细胞中NO的合成,会降低细胞对射线的敏感性;同母本细胞相比,基因转染建立NO含量较高的肿瘤细胞,氧增比（Oxygen Enhancement Ratio,ORE）下降,提示NO参与射线引起的细胞损伤。     

A decision support system using judgmental modeling: a case ofR&D in the pharmaceutical industry

The development of a computerized decision support system for R&D project ranking, monitoring and control in the pharmaceutical industry is described. Using a series of techniques based on a judgmental modeling approach, an overall system has been developed that covers several different aspects of the whole decision making process. Illustrative examples are given to show how the components of the model are used in practice, indicating their place in the overall management process. The results provide evidence supporting the value of such models which help reduce ambiguity by using structured approaches     

一氧化氮合成酶对AQ4N放射增敏作用的影响研究

评价1，4-二-[[2-（二甲氨基-N-氧化物）乙醇]氨基]5，8-双羟基氧化蒽-9，10-二酮（（1，4-bis{[2-（dimethylamino-N-oxide）ethyl]amino}-5，8-dihydroxyanthracene-9，10dione），AQ4N）辐射增敏效果和乏氧选择性，分析一氧化氮合成酶（Inducible nitlogen monoxide synthase，iNOS）对AQ4N代谢活化的影响和作用特点。结果显示AQ4N是一种低毒性的化合物，仅在乏氧条件显示较弱的细胞毒性，可以引起肿瘤细胞凋亡。AQ4N对肿瘤细胞尤其是乏氧肿瘤细胞具有良好的辐射增敏作用。同亲本细胞相比，iNOS基因转染的细胞克隆，仅在乏氧条件下显示出对AQ4N化学敏感性的增强和细胞的G2／M期阻滞。提示iNOS仅在乏氧条件下参与AO4N的代谢活化过程。     

Forebrain lesions differentially affect drinking elicited by dipsogenic challenges and injections of muscimol into the median raphe nucleus.

Injections of muscimol into the median raphe nucleus (MR) elicit intense drinking in normally hydrated rats. To determine whether this response is dependent on forebrain systems mediating other aspects of water intake, the authors examined the effects of lesions of the subfornical organ (SFO), median preoptic nucleus (MnPO), lateral preoptic area (LPO), or lateral hypothalamus (LH) on the drinking. Lesions of the SFO or LH attenuated muscimol-elicited drinking, whereas lesions of the MnPO or LPO increased water intake after the treatment. All of the lesion groups showed a deficit in drinking to injections of polyethylene glycol and at least one of the doses of hypertonic saline. Only the SFO- and LH-lesioned groups showed a suppression of drinking to systemic injections of angiotensin II, suggesting that the drinking elicited by intra-MR injections of muscimol may involve changes in the central circuits mediating angiotensin-induced drinking. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A comparison of the physiological effects of RSU1069 and RB6145 in the SCCVII murine tumour

The physiological and therapeutic effects of the bioreductive agent RSU1069 (80 mg/kg i.p.) and its prodrug RB6145 (240 mg/kg i.p.) were investigated in the SCCVII tumour. Using laser Doppler flowmetry it was found that RSU1069 produced a significant 30% reduction in tumour blood flow 30 min after administration, while RB6145 had no effect. Tumour oxygenation, measured with an Eppendorf oxygen electrode, was unchanged by either agent except for a reduction in values less than 2.5 mmHg at 30 min after injection. Neither agent significantly altered tumour energy metabolism, assessed by 31P magnetic resonance spectroscopy. Both agents significantly increased tumour glucose content by a factor of 1.6-1.7 at 30 min after injection, but had no effect on glucose-6-phosphate or lactate levels. Tumour growth was significantly delayed by heating (42.5 degrees C, 60 min), and although neither RSU1069 nor RB6145 alone had any effect on tumour growth they produced a similar enhancement of the tumour response to heat. The therapeutic effects are consistent with the known conversion in vivo of one third of the pro-drug RB6145 to its active product RSU1069, however the physiological effects of the two agents in the SCCVII tumour are not identical.