Examination of coping resources and family adaptation in mothers and daughters of incestuous versus nonclinical families.

Mother–daughter dyads from incestuous vs nonclinical families were compared in terms of (1) family life stress, (2) problem-solving appraisal, (3) direct coping behaviors, (4) mother–daughter communication, and (5) family adaptation and cohesion. 15 mother–daughter pairs from an incestuous family involving an adult male caretaker were matched on several variables to 16 mother–daughter pairs from a nonclinical family. The results revealed that mothers from the incest group (compared with the nonclinical group) reported greater amounts of family life stress, had more negative perceptions of their problem-solving appraisal, and reported more communication difficulties. The daughters from the incest group appeared to be quite similar to the nonclinical group daughters, although they did acknowledge more family stress. Implications of the results for therapeutic interventions as well as future research were discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Noninvasive assessment of hepatobiliary and renal elimination of cysteinyl leukotrienes by positron emission tomography

N-Acetyl-leukotriene E4 has been identified as an endogenous, biologically less active cysteinyl leukotriene metabolite in rodents and humans. To evaluate the ratio of hepatobiliary to renal elimination of leukotrienes noninvasively by positron emission tomography (PET), we synthesized N-[11C]acetyl-leukotriene E4 by chemical N-acetylation of leukotriene E4. After the intravenous injection of N-[11C]acetyl-leukotriene E4 in normal rats and monkey, uptake by the liver and subsequent excretion into bile were largely responsible for its rapid elimination from blood. In the Cynomolgus monkey, renal excretion of the leukotriene into urine was of additional quantitative importance. Kinetic modeling indicated a mean transit time through the liver of 17 minutes and 34 minutes in rat and monkey, respectively; the corresponding hepatic excretion half-times amounted to 8.5 minutes and 16 minutes. In a mutant rat strain deficient in the hepatobiliary excretion of cysteinyl leukotrienes across the canalicular membrane, the apparent mean liver transit time was 54 minutes, and the hepatic excretion half-time was 29 minutes, indicating prolonged organ storage and metabolism. After transport from the liver back into the circulating blood of omega-oxidized and beta-oxidized metabolites of N-[11C]acetyl-leukotriene E4, renal excretion compensated for the impairment of hepatobiliary elimination in the transport mutant. Metabolite analyses in urine after intravenous injection of N-[3H]acetyl-leukotriene E4 indicated the extensive inactivation of N-acetyl-leukotriene E4 by beta-oxidation from the omega-end in the mutants. A similar shift from hepatobiliary to renal cysteinyl leukotriene elimination was monitored in rats with cholestasis due to bile duct obstruction.(ABSTRACT TRUNCATED AT 250 WORDS)     

Are IQ scores valid for children who are poor readers?

Remedial services for children with reading problems are often allocated according to discrepancies between reading and IQ scores. Results of some recent research suggest, however, that IQ scores of poor readers do not covary with their levels of functioning in other cognitive domains. This study evaluated whether the external validity of IQ scores (from the Wechsler Intelligence Scale for Children—Revised [WAIS—R]) was moderated by reading levels within 2 separate samples of a total of 382 referred children (aged 7–16 yrs). It was found that IQ scores had expected correlations with external measures of verbal, visual-spatial, short-term memory, and arithmetic ability, and that these relations were invariant across levels of reading skill. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Illness attributions and hopelessness depression: The role of hopelessness expectancy.

According to hopelessness theory, hopelessness expectancy is the proximal, sufficient cause of hopelessness depression. Consequently, hopelessness expectancy is viewed as mediating the influence of all other factors on hopelessness depression. Using a longitudinal research design, hopelessness expectancy was examined as a mediator of the relation between illness attributions and hopelessness depression in a sample of 57 adults with rheumatoid arthritis. Although hopelessness expectancy was a strong predictor of hopelessness depression, it moderated rather than mediated the relation between attributions and depression. Finding support for a moderating rather than a mediating model is inconsistent with theory but is consistent with the findings of J. H. Riskind et al (1987). (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Depletion of cortical norepinephrine in rats by 6-hydroxydopamine does not impair performance of a delayed-nonmatching-to-sample task.

Rats were trained on a spatial delayed-nonmatching-to-sample (DNMTS) task, matched for performance, and randomly assigned to treatment with dorsal noradrenergic bundle injections of either 6-hydroxydopamine, to deplete cortical norepinephrine (NE), or vehicle, to control for the effects of surgery. After recovery, there were no significant differences between the groups when retrained on the DNMTS task at retention intervals (RIs) from 0.1 to 15.0 sec. Furthermore, no differences were observed when rats were trained at a 6.0-sec RI filled with distracting stimuli or when dummy information runs were added to increase proactive interference. These results demonstrate that depletion of cortical NE cannot account for the DNMTS performance deficits observed in rats recovered from pyrithiamine-induced thiamine deficiency (R. L. Knoth and R. G. Mair, 1991; J. K. Robinson and Mair, 1992). (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Order acceptance with weighted tardiness

Over the past decade the strategic importance of order acceptance has been widely recognized in practice as well as academic research. This paper examines order acceptance decisions when capacity is limited, customers receive a discount for late delivery, but early delivery is neither penalized nor rewarded. We model a manufacturing facility that considers a pool of orders, and chooses for processing the subset that results in the highest profit. We present several solution methods, beginning with a straightforward application of an approach which separates sequencing and job acceptance. We then develop an optimal branch-and-bound procedure that uses a linear (integer) relaxation for bounding and performs the sequencing and job acceptance decisions jointly. We develop a variety of fast and high-quality heuristics based on this approach. For small problems, beam search runs almost 20 times faster than the benchmark, with a high degree of accuracy, and a branch-and-bound heuristic using Vogel's method for bounding is over 100 times faster with very high accuracy. For larger problems, a myopic heuristic based on the relaxation runs 2000 times faster than the beam-search benchmark, with comparable accuracy.     

The introduction of alkyl,ester, carboxylate,amino, hydroxyl,and phosphate functional groups to the surface of polyethylene

The surface of polyethylene was derivatized with ester, carboxylate, amino, hydroxyl, and phosphate functional groups. α, ω bifunctional alkanes, containing on one end a primary amine, were coupled to oxidized polyethylene through an amide linkage. Polyethylene was first oxidized with chromic acid, the carboxylate groups were converted to the acyl chloride with phosphorus pentachloride, and then reacted with a primary amine to give the covalently bound amide. The copposing ends of the bifunctional alkanes were the methyl, tertiary amine, ester, and hydroxyl groups. The ester was converted to the carboxylate by acid cleavage and the hydroxyl group converted to the phosphate by treatment first with phosphorus oxychloride and then aqueous base. Attenuated total reflection FTIR, XPS, and pH-dependent contact angle wetting were used to characterize the surfaces. The FTIR data were used to confirm the formation of the amide and to detect an undesired carboxylate/ammonium ion complex formed in the presence of trace amounts of water. XPS data were used to confirm expected changes in elemental composition and to provide quantitative estimates of the yields. Oxidation of the polyethylene introduced 5 × 10¹⁴ carboxylate groups/cm² in the 25 Å XPS sampling depth. Of these, up to 98% could be converted to the amide. The advancing contact angle data confirmed the acid/base behavior of the functional groups.     

Responses to depression and their effects on the duration of depressive episodes.

Proposes that the ways people respond to their own symptoms of depression influence the duration of these symptoms. People who engage in ruminative responses to depression, focusing on their symptoms and the possible causes and consequences of their symptoms, will show longer depression than people who take action to distract themselves from their symptoms. Ruminative responses prolong depression because they allow the depressed mood to negatively bias thinking and interfere with instrumental behavior and problem-solving. Laboratory and field studies directly testing this theory have supported its predictions. The author discusses how response styles can explain the greater likelihood of depression in women than men, then integrates this response styles theory with studies of coping with discrete events. The response style theory is compared to other theories of the duration of depression. Finally, suggestions are made that may help a depressed person to stop engaging in ruminative responses and on how response style for depression may develop. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A Web‐based and Group Learning Environment for Introductory Environmental Engineering

The use of computer‐based technology is becoming more prevalent in the classroom. As a part of an educational research project sponsored by the GE Foundation, strategies for augmenting a course, Introduction to Environmental Engineering (CE 280), were investigated including cross‐disciplinary experiences in teamwork, design, and the use of advanced teaching technologies such as the web. Interactive tools to assist student learning were developed and refined. Efforts have focused on developing an extensive website, web‐based quizzes and homework assignments, and tutorials. Base groups were used to provide both intellectual and emotional support to students. This paper summarizes the development of this course and the impact of rapid feedback on the progression of student understanding.