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Basal cell carcinoma (BCC) is the most common type of skin cancer and the incidence of BCC is expected to rise, with increased demand on dermatology resources. Little is known of the effect on people's lives of having skin cancer. The aim of this study was to quantify the handicap caused gy basal cell carcinomas before and after therapy. Forty-four patients (22 males, mean age = 65 yrs, range = 35-81 yrs) with 48 BCCs were recruited and 37 patients completed the study. Each patient completed the UK Sickness Impact Profile (UKSIP) and the Dermatology Life Quality Index (DLQI) at the initial visit to the dermatology clinic, 1 week after treatment and 3 months after treatment. Lesions had been present for a mean of 25 months (range = 1-240 months), their mean diameter was 9.6mm (range = 3-35mm) and the sites were head and neck (79%), trunk (17%) and limbs (4%). There was no relationship between the quality of life score and size of lesion. Overall the scores at presentation were very low, rising 1 week after treatment and falling to below the initial scores at 3 months (mean UKSIP 0.4%, 0.7%, 0.13%; mean DLQI 5.3% 8.7%, 1.2%). BCCs cause little handicap. This may explain the delay in seeking medical attention and should be considered in planning public health education about BCCs. 相似文献
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The L-DOPA and sulpiridinum effects on the enzymatic transporting function of the enterocytes' membrane, were studied in rats under stress. The L-DOPA was shown to hinder the absorption rate of glucose, whereas sulpiridinum was shown to suppress the main enzymes excepting snerase and alkaline phosphatase, to increase the monomeric and hydrolysate glucose transport. The L-DOPA seems to play a modifying role in the regulation and integration of the digestive-transporting function of the enterocytes' membrane in rats under stress. 相似文献
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A. Stelzer Univ.-Ass. Ing. Dipl.-Ing. Dr. techn. A. Springer A. Univ.-Prof. Dipl.-Ing. Dr. techn. 《e & i Elektrotechnik und Informationstechnik》2003,120(3):98-101
This contribution reviews the research work performed at the Johannes Kepler University of Linz, Austria, on the development of oscillators for the microwave and millimeter wave frequency range. This work, performed by the Microelectronics Institute and the Institute for Communications and Information Engineering, covers the range from low GHz frequencies up to 61 GHz and is devoted to applications like mobile communications and sensing. The active devices are based on gallium arsenide (GaAs), silicon germanium (SiGe), and Silicon (Si) and include Gunn-devices, bipolar transistors, and CMOS-technology. 相似文献
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Thoracoscopy provides a minimally invasive technique for the diagnosis and management of many posterior mediastinal masses. Benign neurogenic tumors, esophageal tumors, and bronchogenic cysts all can be approached using video-assisted thoracic surgical (VATS) techniques. Malignant lesions are still best approached via open thoracotomy. VATS techniques allow for less pain and dysfunction and can result in shortened hospital stays. 相似文献
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