Conditional discrimination with conceptual simultaneous and successive cues in the squirrel monkey (Saimiri sciureus).

Studied conditional discrimination, delayed conditional discrimination, the use of a conceptual cue (triangularity, heptagonality, sameness, and difference), and the hierarchy of learning abilities in 4 wildborn adult male squirrel monkeys. After several stages of training in a modified Wisconsin General Test Apparatus, Ss met an 87% criterion for choosing correctly between examplars of the concept sameness and the concept difference, the simultaneous cues (as a function of having been cued by an examplar either of the concept triangularity [cued sameness] or heptagonality [cued difference]), and the successive cues presented in random order. The best S met criterion when the examplars of sameness and difference were presented 16 sec after the withdrawal of the examplar of triangularity or heptagonality, and the other Ss performed successfully with shorter delays. Results are discussed in terms of (1) working memory, (2) the significance for the evolution of behavior of investigating the conceptual capacities of animals, and (3) implications for language in nonhuman animals. (28 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The many faces of character.

This article discusses the many definitions of character in the psychological and nonpsychological literature. A comprehensive, working definition for character is offered that integrates these definitions, the key points of the authors in this issue, and previous treatments of this topic. The major elements of this model include character (a) as a component of personality, (b) as capacities of the self, (c) as the exercise of good judgment, and (d) as the display of moral development. Finally, reasons are provided to underscore the importance for consulting psychologists to have the skills to assess and develop character and to intervene when character-related issues emerge. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The mammalian homologue of mago nashi encodes a serum-inducible protein

OBJECTIVE: We prospectively compared the ability of two techniques--bone scintigraphy with single-photon emission computed tomography (SPECT) of the chest and CT of the chest--to reveal potential osteosarcoma metastases of the lung. SUBJECTS AND METHODS: Our study included 27 patients with osteosarcoma who prospectively underwent both bone scintigraphy with SPECT of the chest and CT of the chest. The imaging results were compared with outcome or pathologic analysis of any lung lesions found. RESULTS: Eight (30%) of the 27 patients had pulmonary metastases. Four of these eight patients had positive results on both CT studies and bone SPECT studies, with additional lesions detected with bone SPECT in two of these four patients. The other four patients with pulmonary metastases had positive results on CT studies, whereas the results of bone SPECT studies remained negative. The results of bone SPECT studies were negative in the 19 patients without pulmonary metastases. CT, however, showed abnormalities in seven (37%) of the 19 patients, which were eventually attributed to benign conditions. CONCLUSION: Negative results on a bone SPECT study of the chest should not be used to exclude the possibility of lung metastases. However, if the results are positive, a bone SPECT study can be used to confirm abnormalities seen on CT scans and may also reveal subtle lesions missed on CT scans.     

Clinical evaluation of bioactive glass in the treatment of periodontal osseous defects in humans

The purpose of this study was to compare the use of bioactive glass to demineralized freeze-dried bone allograft (DFDBA) in the treatment of human periodontal osseous defects. Fifteen systemically healthy patients (6 males and 9 females, aged 30 to 63) with moderate to advanced adult periodontitis were selected for the study. All patients underwent initial therapy, which included scaling and root planing, oral hygiene instruction, and an occlusal adjustment when indicated, followed by re-evaluation 4 to 6 weeks later. Paired osseous defects in each subject were randomly selected to receive grafts of bioactive glass or DFDBA. Both soft and hard tissue measurements were taken the day of surgery (baseline) and at the 6-month re-entry surgery. The clinical examiner was calibrated and blinded to the surgical procedures, while the surgeon was masked to the clinical measurements. Statistical analysis was performed by using the paired Student's t test. The results indicated that probing depths were reduced by 3.07 +/- 0.80 mm with the bioactive glass and 2.60 +/- 1.40 mm with DFDBA. Sites grafted with bioactive glass resulted in 2.27 +/- 0.88 mm attachment level gain, while sites grafted with DFDBA had a 1.93 +/- 1.33 mm gain in attachment. Bioactive glass sites displayed 0.53 +/- 0.64 mm of crestal resorption and 2.73 mm bone fill. DFDBA-grafted sites experienced 0.80 +/- 0.56 mm of crestal resorption and 2.80 mm defect fill. The use of bioactive glass resulted in 61.8% bone fill and 73.33% defect resolution. DFDBA-grafted defects showed similar results, with 62.5% bone fill and 80.87% defect resolution. Both treatments provided soft and hard tissue improvements when compared to baseline (P < or = 0.0001). No statistical difference was found when comparing bioactive glass to DFDBA; however, studies with larger sample sizes may reveal true differences between the materials. This study suggests that bioactive glass is capable of producing results in the short term (6 months) similar to that of DFDBA when used in moderate to deep intrabony periodontal defects.     

Infection of human marrow stroma by human immunodeficiency virus-1 (HIV-1) is both required and sufficient for HIV-1-induced hematopoietic suppression in vitro: demonstration by gene modification of primary human stroma

Patients with human immunodeficiency virus-1 (HIV-1) infection often present with bone marrow (BM) failure that may affect all hematopoietic lineages. It is presently unclear whether this failure reflects a direct viral impairment of the CD34+ hematopoietic progenitor cells or whether the virus affects the BM microenvironment. To study the effects of HIV-1 on the BM microenvironment, we examined the stromal cell monolayers in long-term BM culture (LTBMC), which are the in vitro equivalent of the hematopoietic microenvironment. We assessed the hematopoietic support function (HSF) of human stromal layers by determining the cellular proliferation and colony-forming ability of hematopoietic progenitors from BM cells grown on the stromal layers. We show that the HSF is reduced by in vitro infection of the human stromal cell layer by a monocytotropic isolate of HIV-1 (JR-FL). There is no loss of HSF when the stromal cell layer is resistant to HIV-1 replication, either using murine stromal cell layers that are innately resistant to HIV-1 infection or using human stromal cells genetically modified to express a gene that inhibits HIV-1 replication (an RRE decoy). Decreased HSF was seen using either human or murine hematopoietic cells, if the stromal cells were human cells that were susceptible to HIV-1 infection. These in vitro studies implicate HIV-1 replication in the stroma as the essential component causing decreased hematopoietic cell production in HIV-1 infection.     

Preparing for Program Accreditation Review Under ABET Engineering Criteria 2000: Choosing Outcome Indicators

This paper examines a variety of outcome indicators that might be used by an engineering program in meeting the assessment requirements of ABET Engineering Criteria 2000. Several categories of indicator are identified and key characteristics of these means of assessment are discussed. Also noted are some of the engineering applications of outcome indicators documented on the World Wide Web. Finally, the results of a recent telephone/fax survey on the use of outcome indicators in engineering program assessment are summarized.     

Therapist attitudes as influenced by A-B therapist type, patient diagnosis, and social class.

Attempted to clarify a number of inconsistent and contradictory findings regarding interactions between patient diagnosis (schizophrenic vs. neurotic) and the A-B therapist variable. 37 psychiatric residents completed Kemp's version of the A-B scale. The 10 highest and 10 lowest scorers then rated 4 patient vignettes on likability, discomfort, interest in treating, and prognosis. Patient social class as well as diagnosis were systematically controlled. Results support some of the previous research on likability but provided no support for other A-B * Patient Type interactions. A number of main effects for diagnosis and social class indicate that, in general, residents of both types hold more favorable attitudes toward neurotic and middle-class patients than they do toward schizophrenic and lower-class patients. (23 ref.) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The joint and differential perceived contribution of parents to adolescents' cognitive functioning.

Administered the Personality Research Form (PRF) and the Parent Behavior Form (PBF) to 301 female and 101 male undergraduates; American College Testing Program (ACT) scores were also obtained. Analyses revealed that PRF scales indicative of intellectual orientation and approach to tasks (Understanding, Achievement, and Endurance), as well as ACT scores, were related principally to parental cognitive behaviors (the parents' encouragement of intellectual independence, competence, and curiosity) for both males and females. In addition, differential and joint effects of parents were obtained depending upon the sex of the child. Findings suggest that parental cognitive behaviors, which have received little experimental attention, are saliently related to child intellectual characteristics. (PsycINFO Database Record (c) 2010 APA, all rights reserved)