康复花园

20世纪50年代后,美国日渐泛滥程式化的医疗建筑设计,产生了很多负面影响,一种以病人为本的全新设计理念,在户外辅助治疗的"康复花园"于90年代开始出现.介绍了康复花园的15种设计原则,这些原则有源于经验的,也有基于常识的,是目前所知的最好的康复花园的设计原则,能带来积极的康复效果.现在西方国家的设计师们运用康复花园的经验和理念,在医疗诊断的基础上针对特殊病人对花园的要求设计花园.还有专门为成人和儿童生理复原、精神治疗、老年痴呆、烧伤、艾滋和癌症患者建造的花园等,有很多领域有待深八研究.     

The effects of expressive writing following first myocardial infarction: A randomized controlled trial.

Objective: To assess the effects of expressive writing on health care utilization, clinical variables and subjective quality of life following first myocardial infarction (MI). Methods: One-hundred and seventy-nine first MI patients were randomized to Intervention (N = 88) or Control (N = 91) groups. The intervention group wrote about their thoughts and feelings in relation to having had an MI. Controls wrote in a neutral way about daily activities. The main outcome measures were health care utilization, physical status and subjective quality of life (QOL), assessed after one, two, and five months. Results: One-hundred and fifty-six (87%) completed the study. Five months post-intervention, the intervention group had significantly fewer recorded medical appointments compared to controls. The number of prescribed medicines decreased over time within the intervention group but increased within the control group. The intervention group attended significantly more rehabilitation sessions, reported fewer cardiac related symptoms and had lower diastolic blood pressure five months post-intervention. There was no significant group by time interaction on reported physical health. The group by time interaction on reported mental health approached significance, those in the intervention group reporting greater improvement. Conclusion: Expressive writing may be a beneficial strategy which could be incorporated into rehabilitation interventions to help individuals adjust after first MI. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Implications of fossil fuel constraints on economic growth and global warming

Energy Security and Global Warming are analysed as 21st century sustainability threats.     

The structure of latherin,a surfactant allergen protein from horse sweat and saliva

Latherin is a highly surface-active allergen protein found in the sweat and saliva of horses and other equids. Its surfactant activity is intrinsic to the protein in its native form, and is manifest without associated lipids or glycosylation. Latherin probably functions as a wetting agent in evaporative cooling in horses, but it may also assist in mastication of fibrous food as well as inhibition of microbial biofilms. It is a member of the PLUNC family of proteins abundant in the oral cavity and saliva of mammals, one of which has also been shown to be a surfactant and capable of disrupting microbial biofilms. How these proteins work as surfactants while remaining soluble and cell membrane-compatible is not known. Nor have their structures previously been reported. We have used protein nuclear magnetic resonance spectroscopy to determine the conformation and dynamics of latherin in aqueous solution. The protein is a monomer in solution with a slightly curved cylindrical structure exhibiting a ‘super-roll’ motif comprising a four-stranded anti-parallel β-sheet and two opposing α-helices which twist along the long axis of the cylinder. One end of the molecule has prominent, flexible loops that contain a number of apolar amino acid side chains. This, together with previous biophysical observations, leads us to a plausible mechanism for surfactant activity in which the molecule is first localized to the non-polar interface via these loops, and then unfolds and flattens to expose its hydrophobic interior to the air or non-polar surface. Intrinsically surface-active proteins are relatively rare in nature, and this is the first structure of such a protein from mammals to be reported. Both its conformation and proposed method of action are different from other, non-mammalian surfactant proteins investigated so far.     

Reliability assessment of 3D space frame structures applying stochastic finite element analysis

Throughout design development of satellite structure, stress engineer is usually challenged with randomness in applied loads and material properties. To overcome such problem, a risk-based design is applied which estimates satellite structure probability of failure under static and thermal loads. Determining probability of failure can help to update initially applied factors of safety that were used during structure preliminary design phase. These factors of safety are related to the satellite mission objective. Sensitivity-based analysis is to be implemented in the context of finite element analysis (probabilistic finite element method or stochastic finite element method (SFEM)) to determine the probability of failure for satellite structure or one of its components.     

Information modelling in the construction industry: The information engineering approach

Modelling of knowledge in the construction industry is a cumbersome task because of the large amount of data involved and the lack of automated information-modelling tools. Adoption of a method and an automated CASE (Computer-Aided Software Engineering) tool could eliminate many problems encountered in the development of information systems in the construction industry. In particular, this approach may help to assess the information requirements and define strategies for such information systems. The Information Engineering Method (IEM) is introduced to illustrate hoar the conceptual models may be improved by using this method. Additionally Texas Instruments' Information Engineering Facility (IEF?) CASE tool is described to illustrate the advantages of automating such a method. The introduction of conceptual modelling in the construction industry using data and process models should lead to a better structuring of information. This should result in the development of well defined and structured, not ad hoc, applications. This conceptual modelling approach using information engineering is currently being used at the University of Salford to study the potential development of an integrated database (design, procurement and management of construction) for the construction industry. The case study describes the information analysis phase of the procurement process included towards the end of this paper.