Comparison of urinary excretion of UV-absorbing constituents in healthy subjects and patients with rheumatoid arthritis using analytical isotachophoresis

Analytical isotachophoresis has been applied to the separation of urinary constituents in healthy controls and patients with rheumatoid and osteoarthritis. Various methods of comparing isotachograms have been investigated. Significant differences have been demonstrated between the pattern of UV-absorbing components in patients with rheumatoid arthritis and healthy subjects.     

A simpler analysis of Burrows–Wheeler-based compression

In this paper, we present a new technique for worst-case analysis of compression algorithms which are based on the Burrows–Wheeler Transform. We mainly deal with the algorithm proposed by Burrows and Wheeler in their first paper on the subject [M. Burrows, D.J. Wheeler, A block sorting lossless data compression algorithm, Technical Report 124, Digital Equipment Corporation, Palo Alto, California, 1994], called bw0. This algorithm consists of the following three essential steps: (1) Obtain the Burrows–Wheeler Transform of the text, (2) Convert the transform into a sequence of integers using the move-to-front algorithm, (3) Encode the integers using Arithmetic code or any order-0 encoding (possibly with run-length encoding).     

Coexpression of Bcl-2, c-Myc, and p53 oncoproteins as prognostic discriminants in patients with colorectal carcinoma

Lanepitant is a high-affinity, selective neurokinin-1 receptor (NK-1) and is effective in the dural inflammation model of acute migraine. Lanepitant 30, 80, and 240 mg given orally was evaluated in a double-blind, placebo-controlled crossover study to determine its effect in reducing migraine pain and severity of associated symptoms. Outpatients treated four migraine headaches of moderate or severe pain intensity with study drug according to a randomization schedule. They recorded their pain intensity and severity of migraine-associated symptoms at 30, 60, 90, and 120 min. Although 53 patients were randomly allocated to a treatment sequence, only 40 patients completed all treatments. There was no statistically significant difference in improvement in migraine pain at any time for any of the treatments. Additionally, there was no change in severity of migraine-associated symptoms associated with lanepitant therapy. No adverse events could be attributed to lanepitant. Lanepitant was ineffective orally in treating acute migraine in this trial. This may be due to poor bioavailability during a migraine attack. Alternatively, the neurogenic inflammation hypothesis may not apply to migraine.     

Function morphemes in young children's speech perception and production.

Function morphemes or functors (e.g., articles and verb inflections) potentially provide children with cues for segmenting speech into constituents, as well as for labeling these constituents (e.g., noun phrase [NP] and verb phrase [VP]). However, the fact that young children often fail to produce functors may indicate that they ignore these cues in early language acquisition. Alternatively, children may be sensitive to functors in perception, but omit them in production. In 3 experiments, 2-year-olds imitated sentences that contained English or non-English functors and that were controlled for both suprasegmental and segmental factors. Children omitted English functors more frequently than non-English functors, indicating perceptual sensitivity to familiar vs unfamiliar elements. The results suggest that children may be able to use functors early in language acquisition to solve the segmentation and labeling problems. (PsycINFO Database Record (c) 2010 APA, all rights reserved)