The static bending behavior of porous functionally graded (PFG) micro-plate under the geometrically nonlinear analysis is studied in this article. A small-scale nonlinear solution is established using the Von-Kármán hypothesis and the modified couple stress theory (MCST). To obtain the deflection of the plate, the Reddy higher-order plate theory coupled with isogeometric analysis (IGA) is utilized. The distribution of porosities is assumed to be even and uneven across the plate’s thickness and the effective material properties of porous functionally graded micro-plate are calculated using the refined rule-of-mixture hypothesis. The influence of power index, porosity parameter and material length scale parameter on the nonlinear behaviors of static bending of porous FGM micro-plates are also investigated using several numerical examples.
Transient process of water flow changes the equilibrium conditions of an unsaturated soil, resulting in volume change of a soil. The volume change alters the hydraulic properties of the soil and thus influences the transient process of water flow through the soil. Therefore, the interactive processes between stress-strain behavior and pore-water pressure are the primary processes affecting the mechanical behavior of unsaturated soils. This paper presents coupled elasto-plastic constitutive equations for unsaturated compacted kaolin under consolidated drained and shearing-infiltration conditions. The study focused on the development of the suction increase (SI) yield curve that incorporates changes in matric suction during transient processes. In addition, the relationship of change in specific water volume with respect to net mean stress and matric suction was also proposed by incorporating the hysteresis of soil-water characteristic curve. The simulated results by the proposed constitutive model were compared with those obtained from isotropically consolidated drained tests and shearing infiltration tests of compacted kaolin to verify the proposed model. The simulated results are in close agreement with the experimental results. 相似文献
Background: Rural/remote blood collection can cause delays in processing, reducing PBMC number, viability, cell composition and function. To mitigate these impacts, blood was stored at 4 °C prior to processing. Viable cell number, viability, immune phenotype, and Interferon-γ (IFN-γ) release were measured. Furthermore, the lowest protective volume of cryopreservation media and cell concentration was investigated. Methods: Blood from 10 individuals was stored for up to 10 days. Flow cytometry and IFN-γ ELISPOT were used to measure immune phenotype and function on thawed PBMC. Additionally, PBMC were cryopreserved in volumes ranging from 500 µL to 25 µL and concentration from 10 × 106 cells/mL to 1.67 × 106 cells/mL. Results: PBMC viability and viable cell number significantly reduced over time compared with samples processed immediately, except when stored for 24 h at RT. Monocytes and NK cells significantly reduced over time regardless of storage temperature. Samples with >24 h of RT storage had an increased proportion in Low-Density Neutrophils and T cells compared with samples stored at 4 °C. IFN-γ release was reduced after 24 h of storage, however not in samples stored at 4 °C for >24 h. The lowest protective volume identified was 150 µL with the lowest density of 6.67 × 106 cells/mL. Conclusion: A sample delay of 24 h at RT does not impact the viability and total viable cell numbers. When long-term delays exist (>4 d) total viable cell number and cell viability losses are reduced in samples stored at 4 °C. Immune phenotype and function are slightly altered after 24 h of storage, further impacts of storage are reduced in samples stored at 4 °C. 相似文献
Reductive iodonio-Claisen rearrangement (RICR) involving λ3-iodanes and allyl or substituted-allyl silanes in fluoroalcohols, such as 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) and 2,2,2-trifluoroethanol (TFE), was studied for the synthesis of complex ortho-allyl or substituted-allyl iodoarenes. In comparison to the previously reported condition involving boron trifluoride diethyl etherate, the RICR mediated by fluoroalcohols was found to proceed more effectively. The resulting complex ortho-allyl iodoarenes are useful synthetic intermediates and can be readily converted to various heterocyclic compounds. 相似文献
Plug flow can significantly enhance heat transfer in microchannels as compared to single phase flow. Using an analytical model of flow field, heat transfer in plug flow is investigated. The constant-surface-temperature boundary condition is considered. Three stages of the heat transfer in plugs are identified: (i) development of thermal boundary layer; (ii) advection of heated/fresh fluid in the plug; and (iii) thermally fully developed flow. Due to the transport of heated fluid and fresh fluid within the plug by the recirculating flow, oscillations of the Nusselt number at high Peclet numbers are observed and explained. The effects of the Peclet number and the plug length on the heat transfer process are evaluated. The results show that short plugs are preferable to long plugs since short plugs result in high Nusselt numbers and high heat transfer indices. 相似文献
Nano-silica particles were deposited on acid-etched hydrophilic aluminum (Al) substrates by immersion in well-dispersed nano-silica aqueous suspension and tetramethylamonium hydroxide, followed by a heat treatment. The surface was then further treated by a reaction with fluorosilane. The hydrophobicity, surface morphology, and mechanical properties of the coated Al substrates were investigated, along with their electrochemical properties over time of exposure to two NaCl solutions (0.3% and 3% by weight). All the coated Al surfaces exhibited a water contact angle of 155–158°, i.e., superhydrophobicity. The use of nano-silica suspension significantly enhanced the hydrophobicity of the coated Al. Artificial neural networks were used to provide quantitative understanding in how the microstructure of the treated Al surface contributed to its superhydrophobicity and electrochemical properties. When Ra, total (nano-roughness + micro-roughness) exceeds 450 nm, WCA is greater than 154°, independent of the nano/micro-roughness ratio (RRNM). FESEM and AFM images of these surfaces suggest that a rough two-length-scale hierarchical structure coupled with the low surface energy of fluorosilane topcoat led to the superhydrophobicity of the formed coatings. The coating prepared with the 0.2% nano-silica suspension (vs. other concentrations) featured the highest Young's modulus and the best corrosion protection to the Al substrate in both NaCl solutions. 相似文献
We present a novel way of enhancing the utility of low cost readily available laterite by impregnating it with the α-MnO2 nanorods, thus making a composite material suitable for the removal of As(V) from aqueous media. The composites were synthesized by two methods: (i) ball-milling of a physical blend of laterite with pre-synthesized MnO2; and (ii) in situ formation of MnO2 in the presence of laterite. The BET surface area of composites prepared by both methods was markedly higher compared to un-modified laterite, and the presence of MnO2 in the composite was also confirmed by XRD analysis and TEM microscopy. The adsorption capacity for As(V) was found to be highly pH dependent and the adsorption kinetics followed a pseudo second-order kinetic model. The Langmuir adsorption isotherm was found to be the best model to describe the adsorption equilibrium of As(V) onto un-modified laterite as well both ball-milled and in situ formed composite. The adsorption capacities at room temperature and pH 7.0 were found to be 1.50 mg g?1, 8.93 mg g?1 and 9.70 mg g?1, for un-modified laterite, ball-milled and in situ formed composite, respectively. 相似文献