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排序方式: 共有93条查询结果,搜索用时 578 毫秒
31.
32.
Seley DB Dissing DA Sumant AV Divan R Miller S Auciello O Lepak LA Terrell EA Shogren TJ Fahrner DA Hamilton JP Zach MP 《ACS applied materials & interfaces》2011,3(4):925-930
A fast, simple, scalable technique is described for the controlled, solution-based, electrochemical synthesis of patterned metallic and semiconducting nanowires from reusable, nonsacrificial, ultrananocrystalline diamond (UNCD) templates. This enables the repeated fabrication of arrays of complex patterns of nanowires, potentially made of any electrochemically depositable material. Unlike all other methods of patterning nanowires, this benchtop technique quickly mass-produces patterned nanowires whose diameters are not predefined by the template, without requiring intervening vacuum or clean room processing. This technique opens a pathway for studying nanoscale phenomena with minimal equipment, allowing the process-scale development of a new generation of nanowire-based devices. 相似文献
33.
The drinking behavior and blood pressure responses to i.c.v. administration of artificial cerebrospinal fluid (aCSF) or NG-nitro-L-arginine methyl ester (L-NAME, 10, 250, or 500 micrograms), an inhibitor of nitric oxide synthase, were examined in conscious rats following either osmotic stimulation (1.0 M NaCl, 15 ml/kg, s.c.) or induction of hemorrhage (0.7 ml/min to a 20% blood volume loss). Water intake increased in all animals. L-NAME at doses of 250 and 500 micrograms, but not 10 micrograms, significantly attenuated water consumption induced by both stimuli. The mean arterial blood pressure (MABP), which increased after osmotic stimulation, was maintained at pressor levels by 250 and 500 micrograms of L-NAME, but decreased progressively and reached basal levels after treatment with aCSF and the lowest dose of L-NAME (i.e., 10 micrograms). Hemorrhage significantly decreased MABP in all rats. The fall in blood pressure associated with hemorrhage returned to control levels in animals treated with 250 and 500 micrograms of L-NAME but not in those treated with aCSF or 10 micrograms of L-NAME. These results indicate that nitric oxide is involved in the regulation of drinking behavior and may play an important role in the central control of blood pressure during osmotic stimulation and hypotensive hemorrhage. 相似文献
34.
A new algorithm, based on the minimisation of add and multiply operations, is presented for the implementation of a class of low-order real digital-convolution products. 相似文献
35.
Abstract. In fitting a vector autoregressive process which may include lags up to and including lag K , we may wish to search for the subset vector autoregressive process of size k (where k is the number of lags with non-zero coefficient matrices, k = 1, 2, K ) which has the minimum generalized residual variance. This paper provides a recursive procedure, which is initialized by evaluating all 'forwardand'backward' autoregressions in which k = 1. The recursion then allows one to develop successively all subsets of size k = 2, k = 3 up to k = K .
The optimum subset vector autoregression is found by employing the proposed recursive procedures in conjunction with model selection criteria. This approach is used on simulated data to assess its performance and to re-examine the annual trappings of the Canadian lynx investigated by Tong (1977). 相似文献
The optimum subset vector autoregression is found by employing the proposed recursive procedures in conjunction with model selection criteria. This approach is used on simulated data to assess its performance and to re-examine the annual trappings of the Canadian lynx investigated by Tong (1977). 相似文献
36.
CL Terrell 《Canadian Metallurgical Quarterly》1999,74(1):78-100
Before 1978, amphotericin B and flucytosine were the only drugs available for the treatment of systemic fungal infections. The imidazoles, miconazole and ketoconazole, were introduced during the next 3 years. Intravenously administered miconazole served a limited therapeutic role and is no longer available. Orally administered ketoconazole, an inexpensive, effective, and convenient option for treating mucosal candidiasis, was widely used for a decade because it was the only available oral therapy for systemic fungal infections. During the 1990s, use of ketoconazole diminished because of the release of the triazoles--fluconazole and itraconazole. Fluconazole is less toxic and has several pharmacologic advantages over ketoconazole, including penetration into the cerebrospinal fluid. In addition, it has superior efficacy against systemic candidiasis, cryptococcosis, and coccidioidomycosis. Despite a myriad of drug interactions and less favorable pharmacologic and toxicity profiles in comparison with fluconazole, itraconazole has become a valuable addition to the antifungal armamentarium. It has excellent activity against sporotrichosis and seems promising in the treatment of aspergillosis. Itraconazole has replaced ketoconazole as the therapy of choice for nonmeningeal, non-life-threatening cases of histoplasmosis, blastomycosis, and paracoccidioidomycosis and is effective in patients with cryptococcosis and coccidioidomycosis, including those with meningitis. Further investigation into the development of new antifungal agents is ongoing. 相似文献
37.
JA Campain KL Terrell JA Tomczak EJ Shpall LS Hami GS Harrison 《Canadian Metallurgical Quarterly》1997,3(5):273-281
Genetic alteration of stem cells ex vivo followed by bone marrow transplantation could potentially be used in the treatment of numerous diseases and malignancies. However, there are many unanswered questions as to the best source of hematopoietic cells for long-term reengraftment and the most effective way to introduce foreign genes into this target cell. We have compared retroviral-mediated gene transfer into CD34+-enriched cells derived from peripheral blood (PB), bone marrow (BM), or fetal umbilical cord blood (CB). Cells from all three sources that had been expanded ex vivo in the presence of stem cell factor (SCF), interleukin-3 (IL-3), IL-6, and granulocyte colony-stimulating factor (G-CSF) showed transduction efficiencies ranging from 5-45%, as measured by acquisition of G418 resistance. The average efficiencies of gene transfer from multiple experiments for PB, BM, and CB were not statistically different. To determine the effect of ex vivo expansion on gene transfer into CB CD34+ cells, we compared the transduction efficiencies of cells exposed to virus immediately after harvest and CD34 selection or after 6 days of culture CD34+ CB cells were more effectively transduced after expansion in culture, showing gene transfer efficiencies 3- to 5-fold higher on day 6 compared with day 0. Last, we examined retroviral transduction via spinoculation of CB CD34+ cells and found it to be approximately as effective as our standard transduction with no significant loss of cell viability as measured by colony formation in semi-solid medium. 相似文献
38.
39.
Terrell David L.; Perry Aubrey M.; Ballard James M. II 《Canadian Metallurgical Quarterly》2002,57(10):789
Reports the death of Vernon Wellington Sparks, Sr. (1920-2002). The authors discuss his contributions to the evolution of clinical psychology as well as his various personal and professional accomplishments. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
40.
Andersen Terrell N. Vanorden Naola Schlitt W. Joseph 《Metallurgical and Materials Transactions A》1980,11(8):1421-1428
Effects of nitrate ions, nitrous acid, sulfur dioxide, and ferric ions on the corrosion of mild steel in unstirred, concentrated
sulfuric acid were determined in laboratory tests. Nitrate and nitrous acid at levels up to 1000 ppm accelerate corrosion.
At concentrations greater than 1000 ppm nitrate passivates the steel. Sulfur dioxide and ferric ions have no detectable influence
on the corrosion. Reaction mechanisms are presented to explain the observed effects. The impact of nitrogen oxides on the
storage and handling of sulfide smelter by-product acid is discussed. 相似文献