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21.
L. Kokkinidis et al (see record 1981-08105-001) reviewed animal research investigating the mechanisms of action of amphetamine and discussed the implications of this research for the development of animal models of paranoid schizophrenic psychosis. On the basis of their review of the literature, they hypothesized that abnormalities in neurotransmitter systems containing norepinephrine and dopamine were associated with this psychotic process. The present authors believe that the involvement of catecholamines in psychosis is determined by complex pre- and postsynaptic events not adequately discussed by Kokkinidis et al. Furthermore, open-field behavioral changes produced in the rat by amphetamines are not as simple nor are their neural substrates as well defined as Kokkinidis et al suggest. (56 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
22.
Charles Ribardo Theodore T. Allen 《Quality and Reliability Engineering International》2003,19(3):227-240
To achieve high process yields or ‘six sigma’ quality, engineers often need to evaluate and optimize processes that are characterized by multiple quality characteristics. Existing desirability functions weigh together multiple objectives but they have a number of limitations. Most importantly, available desirability functions do not explicitly account for the combined effect of the mean and the dispersion of the quality characteristic. Therefore, it is easy to incur excessive expenditures or unknowingly to fail to achieve targeted yields. In this paper, a desirability function is proposed that addresses these limitations. This function conservatively estimates the ‘effective yield’ under assumptions described in the ‘six sigma’ literature. We use an arc‐welding application to illustrate how the proposed desirability function can yield a substantially higher level of quality as well as a more accurate assessment of the process capability than available alternatives. We suggest that the proposed desirability function should be used to facilitate multicriterion optimization when dispersion data are available. Copyright © 2003 John Wiley & Sons, Ltd. 相似文献
23.
Though condensed between the stages of design and completion, the conventional process of designing a building is time consuming, involving various stakeholders, planning processes and a wide team of consultants and contractors. What happens, though, if the time period of an architect's involvement is expanded? How might a more process-orientated approach shift the role of the architect? Tobias Armborst, Daniel D'Oca and Georgeen Theodore , principals of Interboro Partners in New York, describe how they have developed projects that have sought opportunities in expanding the timescale and remit of traditional practice. 相似文献
24.
José Miguel Pasini Claudio Corgnale Bart A. van Hassel Theodore Motyka Sudarshan Kumar Kevin L. Simmons 《International Journal of Hydrogen Energy》2013
The United States Department of Energy (DOE) has published a progression of technical targets to be satisfied by on-board rechargeable hydrogen storage systems in light-duty vehicles. By combining simplified storage system and vehicle models with interpolated data from metal hydride databases, we obtain material-level requirements for metal hydrides that can be assembled into systems that satisfy the DOE targets for 2017. We assume minimal balance-of-plant components for systems with and without a hydrogen combustion loop for supplemental heating. Tank weight and volume are driven by the stringent requirements for refueling time. The resulting requirements suggest that, at least for this specific application, no current on-board rechargeable metal hydride satisfies these requirements. 相似文献
25.
26.
Theodore P. Pavlic Kevin M. Passino 《Engineering Applications of Artificial Intelligence》2009,22(3):482-489
We consider the optimal control design of an abstract autonomous vehicle (AAV). The AAV searches an area for tasks that are detected with a probability that depends on vehicle speed, and each detected task can be processed or ignored. Both searching and processing are costly, but processing also returns rewards that quantify designer preferences. We generalize results from the analysis of animal foraging behavior to model the AAV. Then, using a performance metric common in behavioral ecology, we explicitly find the optimal speed and task processing choice policy for a version of the AAV problem. Finally, in simulation, we show how parameter estimation can be used to determine the optimal controller online when density of task types is unknown. 相似文献
27.
Marcus A. Worsley Peter J. Pauzauskie Sergei O. Kucheyev Joseph M. Zaug Alex V. Hamza Joe H. Satcher Theodore F. Baumann 《Acta Materialia》2009,57(17):5131-5136
Here, we present the synthesis and characterization of low-density single-walled carbon nanotube-based aerogels (SWNT-CA). Aerogels with varying nanotube loading (0–55 wt.%) and density (20–350 mg cm?3) were fabricated and characterized by four-probe method, electron microscopy, Raman spectroscopy and nitrogen porosimetry. Several properties of the SWNT-CAs were highly dependent upon nanotube loading. At nanotube loadings of 55 wt.%, shrinkage of the aerogel monoliths during carbonization and drying was almost completely eliminated. Electrical conductivities are improved by an order of magnitude for the SWNT-CA (55 wt.% nanotubes) compared to those of foams without nanotubes. Surface areas as high as 184 m2 g?1 were achieved for SWNT-CAs with greater than 20 wt.% nanotube loading. 相似文献
28.
The sorption of n-butane, propane, and ethane in ethylcellulose has been investigated between 0 and 200 mm Hg pressure over the temperature range from 30 to 70°C. Sorption isotherms of n-butane, propane, and ethane in ethylcellulose suggest that both Henry's law and the Langmuir forms of sorption, are operative. Sorption data were analyzed using the dual sorption model and sorption parameters determined. The sorption attributed to the Langmuir mode decreases as the temperature increases. This result indicates that the nonlinear Langmuir mode of sorption is more characteristic of the glassy state than sorption represented by the Henry's law mode. It was found that sorption attributed to the Henry's law and Langmuir modes decreases as the molecular size of gaseous hydrocarbon penetrants decrease. In this study, the molecular size of gaseous molecule decreased as the gases studied changed from n-butane to propane to ethane. A correlation of the Henry's law constants for the solution of n-butane, propane, and ethane in ethylcellulose with the Lennard-Jones force constants, ?/k at different temperatures was also determined. The temperature dependence of the Henry's law constants were correlated by a van't Hoff relationship and heats of sorption determined. 相似文献
29.
Vogler Roger E.; Weissbach Theodore A.; Compton John V.; Martin George T. 《Canadian Metallurgical Quarterly》1977,45(2):267
Evaluated the therapeutic potential of learning techniques in changing abusive drinking patterns and achieving moderation using 80 regularly employed drinkers with intact families, remaining self-esteem, but also alcohol-related problems. The following procedures were studied: videotaped self-confrontation of drunken behavior, aversion training for overconsumption, discrimination training for blood alcohol concentration, alternatives training, behavior counseling, and alcohol education. All the techniques were applied to Group 1 (n?=?23), the last 4 to Group 2 (n?=?19), alcohol education only to Group 3 (n?=?21), and the last 3 to Group 4 (n?=?17). Tests administered included the California Psychological Inventory, the Marlowe-Crowne Social Desirability Scale, and Rotter's Internal–External Locus of Control Scale. During the 1st yr of follow-up, significant decreases in alcohol intake were found for all groups, and the percentage of moderate drinkers changed from 0% to 62.5%. Significant differences between groups were not found. The effects on outcome of a large variance in pretreatment S characteristics such as alcohol intake, the amount of possible change in intake, the program's learning orientation, and blind follow-up are discussed as factors that may partially account for the lack of differential treatment effects. It is concluded that moderation is a more attainable and feasible goal for problem drinkers than for chronic alcoholics. (36 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
30.
Stochastic structural analysis can assess whether a fabricated object will break under real-world conditions. While this approach is powerful, it is also quite slow, which has previously limited its use to coarse resolutions (e.g., 26 × 34 × 28). We show that this approach can be made asymptotically faster, which in practice reduces computation time by two orders of magnitude, and allows the use of previously-infeasible resolutions. We achieve this by showing that the probability gradient can be computed in linear time instead of quadratic, and by using a robust new scheme that stabilizes the inertia gradients used by the optimization. Additionally, we propose a constrained restart method that deals with local minima, and a sheathing approach that further reduces the weight of the shape. Together, these components enable the discovery of previously-inaccessible designs. 相似文献