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排序方式: 共有79条查询结果,搜索用时 203 毫秒
61.
Manu Huttunen Lauri Nygren Teemu Kinnarinen Bjarne Ekberg Tuomo Lindh Jero Ahola 《Drying Technology》2020,38(4):460-475
AbstractHorizontal vacuum belt filters are used for continuous solid–liquid separation in a wide variety of industrial processes. Despite the low pressure difference (usually Δp?<?0.8?bar), the high air pumping requirement to maintain the pressure difference results in considerable energy consumption. In this article, the specific energy consumption of vacuum filtration and air flow rates of a pilot-scale horizontal vacuum belt filter unit are investigated. The results show that a claw-type vacuum pump consumes only half the energy compared to a conventional liquid ring vacuum pump at corresponding operating points. A comparison between the specific energy consumption of vacuum filtration and thermal drying of the filter cake to zero moisture revealed that vacuum filtration accounted for less than half of the total energy consumption in the applied experimental conditions at Δp?=?0.2–0.5?bar. The majority of the total pumping requirement of the pilot-scale filter resulted from leaks, and only 2–25% of the air flow found its way through the cake and the filter medium. The results suggest that there is a combination of the pressure difference level and the mass of solids deposited per filtration area that together with thermal drying consumes the least amount of energy per solids mass. 相似文献
62.
Jobin Varghese Tuomo Siponkoski Mikko Nelo Mailadil Thomas Sebastian Heli Jantunen 《Journal of the European Ceramic Society》2018,38(4):1541-1547
The α-MoO3 ceramics were prepared by uniaxial pressing and sintering of MoO3 powder at 650 °C and their structure, microstructure, densification and sintering and microwave dielectric properties were investigated. The sintering temperature of α-MoO3 was optimized based on the best densification and microwave dielectric properties. After sintering at 650 °C the relative permittivity was found to be 6.6 and the quality factor was 41,000 GHz at 11.3 GHz. The full-width half-maximum of the A1g Raman mode of bulk α-MoO3 at different sintering temperatures correlated well with the Qf values. Moreover, the sintered samples showed a temperature coefficient of the resonant frequency of ?25 ppm/°C in the temperature range from ?40 to 85 °C and they exhibited a very low coefficient of thermal expansion of ±4 ppm/°C. These microwave dielectric properties of α-MoO3 will be of great benefit in future MoO3 based materials and their applications. 相似文献
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Jayendra Z. Patel Dr. Tapio J. Nevalainen Dr. Juha R. Savinainen Yahaya Adams Dr. Tuomo Laitinen Robert S. Runyon Miia Vaara Stephen Ahenkorah Dr. Agnieszka A. Kaczor Dina Navia‐Paldanius Dr. Mikko Gynther Niina Aaltonen Dr. Amit A. Joharapurkar Dr. Mukul R. Jain Dr. Abigail S. Haka Prof. Frederick R. Maxfield Dr. Jarmo T. Laitinen Dr. Teija Parkkari 《ChemMedChem》2015,10(2):253-265
At present, inhibitors of α/β‐hydrolase domain 6 (ABHD6) are viewed as a promising approach to treat inflammation and metabolic disorders. This article describes the development of 1,2,5‐thiadiazole carbamates as ABHD6 inhibitors. Altogether, 34 compounds were synthesized, and their inhibitory activity was tested using lysates of HEK293 cells transiently expressing human ABHD6 (hABHD6). Among the compound series, 4‐morpholino‐1,2,5‐thiadiazol‐3‐yl cyclooctyl(methyl)carbamate (JZP‐430) potently and irreversibly inhibited hABHD6 (IC50=44 nM ) and showed ~230‐fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL), the main off‐targets of related compounds. Additionally, activity‐based protein profiling indicated that JZP‐430 displays good selectivity among the serine hydrolases of the mouse brain membrane proteome. JZP‐430 has been identified as a highly selective, irreversible inhibitor of hABHD6, which may provide a novel approach in the treatment of obesity and type II diabetes. 相似文献
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Controlled partial neutralization of an amphoteric aminomethylphosphonium functional ion exchange resin (Lewatit TP-260) was investigated. The particular goal of controlled neutralization was to replace H+ in the acidic phosphonium groups with Na+ ions but leave the basic amino groups protonated. In this manner, metals’ sorption is enhanced and undesired pH changes during the metal separation process are avoided. The conjugate bases of organic weak acids (sodium formiate, sodium acetate and sodium citrate), sodium phosphate and NaOH were studied as neutralizing agents. The organic acid salts and sodium phosphate were all found to be suitable. Lengthening the neutralization cycle and using more concentrated neutralization agents were found to yield higher extents of neutralization and more uniform profiles along a resin bed. Concentrated NaOH also neutralized the amine group from the resin. With dilute NaOH, desired extent of neutralization was not achieved within a reasonable time. The effect of partial neutralization on metal sorption was tested with dynamic single column experiments. 5.5 BV of Ag–NaCl solution could be purified from Ca, Mg, Pb and Zn when the resin was partially neutralized with 2.0 M NaAc. With the acid form resin, the impurity metals broke through at 1.0 BV. 相似文献
68.
An adaptive fuzzy control system to maximize rough turning productivity and avoid the onset of instability 总被引:1,自引:0,他引:1
Juho Ratava Mikko Rikkonen Ville Ryyn?nen Johanna Lepp?nen Tuomo Lindh Juha Varis Inga Sihvo 《The International Journal of Advanced Manufacturing Technology》2011,53(1-4):71-79
This paper presents a new method to improve cutting efficiency for steel rough turning. To date, most efforts aimed at improving productivity during cutting operations have concentrated on optimizing material handling to and from the machinery. Here, the focus is on improving the efficiency of the turning operation itself. The approach is to control feed rate to raise machine power to a maximum safe level while avoiding the onset of cutting instability. The measure of machine power comes directly from the spindle motor and is held below the cutting machine??s power capacity. Detecting the onset of instability relies on interpreting data that come from installed instrumentation. A fuzzy inference system processes the inputs and makes the final control decisions. The prototype system was tuned using data collected in a variety of cutting situations. Subsequent testing of the tuned control system showed that it was capable of successfully maximizing power usage while still avoiding the onset of instability. 相似文献
69.
Antti A Mero Tuomo Ojala Juha J Hulmi Risto Puurtinen Tuomo AM Karila Timo Seppälä 《Journal of the International Society of Sports Nutrition》2010,7(1):1-8
Background
The effect of moderate dehydration and consequent fluid replenishment on short-duration maximal treadmill performance was studied in eight healthy, fit (VO2max = 49.7 ± 8.7 mL kg-1 min-1) males aged 28 ± 7.5 yrs.Methods
The study involved a within subject, blinded, crossover, placebo design. Initially, all subjects performed a baseline exercise test using an individualized treadmill protocol structured to induce exhaustion in 7 to 10 min. On each of the three subsequent testing days, the subjects exercised at 70-75% VO2max for 60 min at 29-33°C, resulting in a dehydration weight loss of 1.8-2.1% body weight. After 60 min of rest and recovery at 22 C, subjects performed the same treadmill test to voluntary exhaustion, which resulted in a small reduction in VO2max and a decline in treadmill performance by 3% relative to the baseline results. Following another 60 min rest and recovery, subjects ingested the same amount of fluid lost in the form of one of three lemon-flavored, randomly assigned commercial drinks, namely Crystal Light (placebo control), Gatorade® and Rehydrate Electrolyte Replacement Drink, and then repeated the treadmill test to voluntary exhaustion.Results
VO2max returned to baseline levels with Rehydrate, while there was only a slight improvement with Gatorade and Crystal Light. There were no changes in heart rate or ventilation with all three different replacement drinks. Relative to the dehydrated state, a 6.5% decrease in treadmill performance time occurred with Crystal Light, while replenishment with Gatorade, which contains fructose, glucose, sodium and potassium, resulted in a 2.1% decrease. In contrast, treatment with Rehydrate, which comprises fructose, glucose polymer, calcium, magnesium, sodium, potassium, amino acids, thiols and vitamins, resulted in a 7.3% increase in treadmill time relative to that of the dehydrated state.Conclusions
The results indicate that constituents other than water, simple transportable monosaccharides and sodium are important for maximal exercise performance and effective recovery associated with endurance exercise-induced dehydration. 相似文献70.
Eveliina Takasuo Stefan Holmström Tuomo Kinnunen Pekka H. Pankakoski Ensio Hosio Ilona Lindholm 《Nuclear Engineering and Design》2011,241(4):1196-1205
The coolability of ex-vessel core debris is an important issue in the severe accident management strategy of, e.g. the Nordic boiling water reactors. In a core melt accident, the molten core material is expected to discharge into the containment and form a porous debris bed on the pedestal floor of a flooded lower drywell. The debris bed generates decay heat which must be removed by boiling in order to stabilize the debris bed and to prevent local dryout and possible re-melting of the material. The STYX test facility which consists of a cylindrical bed of irregular alumina particles has been used to investigate the effect of lateral coolant inflow on the dryout heat flux of the particle bed. The lateral flow was achieved by downcomers attached on the sides of the test rig. The downcomers provide coolant into the lower region of the bed by natural circulation. Both homogenous and stratified bed configurations have been examined. It was observed that the dryout heat flux is increased by 22-25% for the homogenous test bed compared to the case with no lateral flooding. For the stratified configuration with a fine particle layer on top of the bed, no significant increase in the dryout heat flux was observed. The experiments have been analyzed by using the MEWA-2D code. Models which include explicit consideration of gas-liquid friction were used in the calculations in order to realistically capture the lateral flow configuration. 相似文献