Effect of the prolonged use of streptomycin as well as streptomycin in combination with tubazid on the bioelectrical activity of the brain in experimental tuberculosis]

The effect of streptomycin used alone and in combination with tubazid on the brain electric activity was studied in chronic experiments on rabbits with tuberculosis. The electrocorticographical investigations showed that the antibacterial treatment lowered the spontaneous electric activity and reactive capacity of the cortex. It was evident from a narrow amplitude of the main rythm, coefficient and energy of synchronization on rythmic photostimulation and paroxysmal activity withing the theta range. With the account of the high therapeutic effect of the antibacterial treatment evident from minimum affection of the organs with tuberculosis, the above changes in the electrocorticogrammes should be attributed to the neurotropic effect of the drug and not to tuberculosis intoxication.     

Pathology of the lymphopharyngeal ring in children

The condition of tonsils was studied in 9612 children of organized establishments aged up to 14 years. Diseases of the tonsils were found in 34.8% cases (simple hyperplasia in 35.6%, chronic tonsillitis in 64.4% cases). In 63.3% cases chronic tonsillitis was accompanied by tonsillar hypertrophy. In 84% cases it proceeded with signs of tonsillogenous intoxication. Lymphopharyngeal ring pathology was more often than not found in 7-14 year old children (44.6%). The authors discuss problems of pathogenesis, clinical course, diagnostics and treatment of lymphopharyngeal ring pathology in children. They suppose that tonsillar pathology in children is to be considered as a systemic disease, the leading role in its pathogenesis seems to belong to the total lymphoid system of the organism. Proceeding from the fact that the tonsils in children are of great functional importance as they take part in the formation of local and general defensive immunologic reactions of the organism, the authors consider that in children it is necessary to give preference to conservative methods in the treatment of chronic tonsillitis.     

Effect of peridural block on the adrenal cortex function after operations on the biliary tract

In patients operated upon with the use of peridural blockade the concentration of 11-OCS in blood plasma does not exceed the normal values both during surgery and in the immediate postoperative period. In patients operated upon under conditions of the routine combined narcosis an increased secretion of corticosteroids was observed.