Serial measurements of body composition in obese subjects during a very-low-energy diet (VLED) comparing bioelectrical impedance with hydrodensitometry

Bioelectrical impedance analysis (BIA) is a convenient, inexpensive, and noninvasive technique for measuring body composition. BIA has been strongly correlated with total body water (TBW) and also has been validated against hydrodensitometry (HD). The accuracy and clinical utility of BIA and HD during periods of substantial weight loss remain controversial. We measured body composition in moderately and severely obese patients serially using both methods during a very-low-energy diet (VLED). Mean initial weight in these patients was 116 (+/-30) kg (range, 74-196 kg). Mean weight loss was 24 (+/-13) kg with a decrease in fat mass (FM) by HD of kg (p < 0.001) and a decrease in fat-free mass (FFM) of 3.6 kg (p < 0.05). Loss of FFM is best predicted by the rate (kg/wk) of weight loss (r2 = 0.86, p < 0.0001). FFM, as predicted from BIA equations, was highly correlated with FFM as estimated by HD during all testing sessions (r = 0.92-0.98). Although highly correlated, BIA overestimated FFM relative to HD and this difference appeared to be more pronounced for taller patients with greater truncal obesity. Although the discrepancy was no greater during weight-loss treatment, the level of disagreement was considerable. Therefore, the two methods cannot be used interchangeably to monitor relative changes in body composition in patients with obesity during treatment with VLED. The discrepancy between BIA and HD may be caused by body mass distribution considerations and by perturbations in TBW which affect the hydration quotient for FFM (BIA) and/or which affect the density constants for FFM and FM (HD).     

Influence of oxides on the stability of zinc foam

The influence of oxides on the stabilisation of zinc foam made by foaming-compacted powder mixtures has been investigated by varying the oxide content in the zinc powder used by oxidation and reduction. Optical, scanning electron and transmission electron microscopy as well as energy dispersive X-ray mapping were used to determine the oxide distribution, morphology and structure in the foams. The study revealed that with increase in the oxide content of the foam, the maximum expansion and expansion rate increased. Small amount of nano-sized oxide particles and their cluster, which are randomly distributed, were observed within the bulk of foam. But the major fraction of oxides is observed on the surface of pores in the form of clusters. These clusters are distributed uniformly all over the surface. Effect of these oxides on the stability of foam is discussed. The formation of satellite pores, which is characteristic signature of zinc foams, and their stability, is investigated.     

Tensile, creep, and ABI tests on sn5%sb solder for mechanical property evaluation

Sn5%Sb is one of the materials considered for replacing lead containing alloys for soldering in electronic packaging. We evaluated the tensile properties of the bulk material at varied strain-rates and temperatures (to 473K) to determine the underlying deformation mechanisms. Stress exponents of about three and seven were observed at low and high stresses, respectively, and very low activation energies for creep (about 16.7 and 37.7 kJ/mole) were noted. A maximum ductility of about 350% was noted at ambient temperature. Creep tests performed in the same temperature regime also showed two distinct regions, albeit with slightly different exponents (three and five) and activation energy (about 54.4 kJ/mole). Ball indentation tests were performed on the shoulder portions of the creep samples (prior to creep tests) using a Stress-Strain Microprobe^@ (Advanced Technology Corporation) at varied indentation rates (strain-rates). The automated ball indentation (ABI) data were at relatively high strain-rates; however, they were in excellent agreement with creep data, while both these results deviated from the tensile test data. Work is planned to perform creep at high stresses at ambient and extend ABI tests to elevated temperatures.     

Epoch Extraction by Phase Modelling of Speech Signals

Epochs are instants of significant excitation of vocal-tract system in speech production process. In this paper, we attempt to extract information about epochs from phase spectra of speech signals. The phase spectrum of speech is modelled as the response of an allpass (AP) filter, and the resulting error signal is used for epoch extraction. The parameters of AP model are estimated by imposing sparsity constraints on the error signal. The error signal, thus obtained, exhibits prominent peaks at epoch locations. The epochal candidates obtained from the error signal are refined using a dynamic programming algorithm. The performance of the proposed method is consistent across genders and is comparable with the state-of-the-art methods.     

Metallographic investigations of the failed superheater tubes used in liquid hydrogen plant

2.25Cr–1Mo low alloy steel tubes of diameter 42.5 mm ID and 46.5 mm OD were used in superheater of liquid hydrogen plant. This superheater had 10 rows of tubes for carrying naphtha and steam and is heated by flue gas. The flue gas directly impinges on the first three tubes of the tube bank. A failure occurred in the first tube leading to the removal of a portion of the material causing to shut down of the plant.Detailed metallurgical investigations were carried out to understand the cause of failure. This paper brings out the metallographic investigations on the failed tubes and the necessary remedial actions thereon.     

Stereotaxic surgery of temporal lobe epilepsy

Forty patients with temporal epilepsy were operated on with a stereotaxic technique. Eleven patients had a unilateral localization of the epileptic focus, and in 29 bitemporal foci were diagnosed. In evaluating the results of the treatment the dynamics of the epileptic fits, the peculiarities of changes in the mental status, and the degree of social adaptation were taken into consideration. A postoperative improvement was achieved in 73% of the patients with monotemporal lesions, while in those with bitemporal epilepsy and distinct persistent mental disorders the state was improved in 44% of the cases. Indications for the choice of the zone of destruction depending on the clinical peculiarities of the lesion are presented.     

Changes in nitrogen metabolism in young cattle following ultraviolet irradiation and feeding on urea

Some indexes of nitrogen metabolism in blood, rumen content and urine of bull-calves fed on urea were studied as affected by UV-radiation. The content of protein, nonprotein, amine nitrogen, urea and ammonia in the rumen content and blood as well as as intensity of urea nitrogen and ammonia excretion with urine were determined. It is established that when 25% of protein necessary for the organism was replaced in the ration by urea, UV-radiation with a dose of 120 merg/h-m2 lowers already at the beginning of irradiation the amount of amine nitrogen and further the protein one in the young cattle rumen content. In blood of the irradiated bull-calves at the beginning of irradiation the level of amine nitrogen decreases, the level of nonprotein nitrogen lowers with a longer irradiation. The content of protein nitrogen in blood at that time increases. It was found that the content of ammonia in the bull-calves rumen during the first twenty-hours lowers, the amount of urea in blood does not change essentially. Simultaneously the ammonia excretion with urine intensifies, at the same time the excretion of urea nitrogen with urine does not differ essentially from that in the control bull-calves. In the bull-calves under study the nitrogen balance and average daily gains increase that may testify to the fact that UV-radiation in the applied dose stimulates a more complete utilization of urea nitrogen for the synthesis processes in the organism.     

Photooxidation of P-960 and photoreduction of P-800 (bacteriopheophytin b-800) in reaction centers from Rhodopseudomonas viridis

CT scans of 9 patients with orbital pseudotumor (bilateral in 6 and unilateral in 3) showed findings distinct from those observed in Graves' ophthalmopathy. In bilateral involvement, they ranged from localized mass lesions to complete obiliteration of normal orbital CT anatomical landmarks; diffuse or multifocal lesions involving the posterior globe and muscle insertions were most typical of the diagnosis. However, findings in unilateral psedotumor may be indistinguishable from orbital mass lesions other than Graves' ophthalmopathy. Serial CT scans were used to show progression of disease and response to treatment.     

Influence of the dentate fascia on the sensory responses of neurons in hippocampal field CA3

In experiments with unanaesthetized rabbits the influences of electric stimulation of the dentate fascia (DF) on the extracellularly recorded spontaneous and evoked activity of the CA3 neurones were investigated. Stimulation of a fixed locus in the DF during recording in the CA3 by a microelectrode, shifted along the longitudinal axis of the hippocampus, supported the notion of the topical, "segmental" organization of connections between the DF and CA3. A relatively narrow "active zone" (approximately 700 nm) appeared in the CA3 during the threshold DF stimulation: it was bordered by zones with predominantly inhibitory responses to stimulation. The CA3 neurones in the "active zone" rapidly lost their reactivity to sensory stimuli. In the "inhibitory" and "zero" zones the normal level of reactivity to sensory stimuli was preserved.     

Morphological effects in rats following a 22-day space flight

A morphological examination of 27 rats flown onboard the biosatellite and sacrificed on the 1st-2nd and 26-27th postflight days demonstrated no significant changes in the structural organization of the vital organs and systems of the animal body. It was, however, found that the space exposure induced morphologically detectable changes in the musculo-skeletal system, hemo- and lymphopoiesis, hypothalamic-pituitary-adrenal system and the juxtaglomerular apparatus of the kidneys. The changes were reversible and nonspecific, and could be seen in animals exposed to ground-based hypokinetic and other stress experiments. Postflight the animals developed some reactions that were similar to those in humans. This helps to identify the morphological substrate of certain changes in the human body and to investigate their pathogenesis.