Paraventricular nucleus: changes in the medial and lateral cell groups during dehydration and rehydration in the rat

Cell area, percentage of cells with more than one nucleolus, and percentage of cells with the nucleolus apposed to the nuclear membrane (marginated) were compared in the medial and lateral magnocellular portions of the paraventricular nucleus (PVN) during water deprivation and voluntary rehydration. Lateral cells were larger and had a greater percentage of cells with multiple nucleoli in all conditions of deprivation and rehydration. In addition laterals were found to have more cells with marginated nucleoli in these cells with only one nucleoli. Medial and lateral cells showed similar responses to deprivation and rehydration.     

Pharmacokinetics of theophylline in patients following short-term intravenous infusion

Serum theophylline concentrations after intravenous administration of a new short-term infusion (Euphyllin Kurzzeitinfusion) were measured in 50 out-patients with chronic obstructive airways disease (COAD). An intravenous infusion of theophylline ethylenediamine 480 mg (corresponding to approximately 350 mg anhydrous theophylline) in 50 ml isotonic solution was given in 20 min. Blood samples were taken beforehand and 25 to 30 min and 1, 3 and 6 h after starting the infusion. 86% of the patients had a one-hour serum level in he therapeutic range of 8.20 mg/l, and 2 h later, this was true of 64% of the patients. The short-term infusion was well tolerated, even in cases with unknown high pre-infusion serum levels. Pertinent pharmacokinetic parameters were determined, such as total body clearance, apparent volume of distribution, and half-life of elimination. Geometric mean an 95%-confidence limits, derived from the log-normal distribution of these parameters, were: Cl = 0.044 (0.018-0.190) l/h/kg ideal body weight, Vd = 0.451 (0.258-0.789) l/kg ideal body weight, and t 1/2(el) = 7.1 (2.6-19.1) h.     

Alternating current impedance measurements of the vitreous carbon/sodium polysulphide interphase at 350°C

Ac impedance measurements have been made at the vitreous carbon—sodium polysulphide (liquid) interphase at a temperature of 350°C. Molten Na₂S₃ and Na₂S₅ were employed.The impedance data confirm that the reaction is purely diffusion-controlled at relatively low overpotentials and that a film is present on the electrode when the cathodic limiting current is reached. At extreme cathodic potentials, sodium deposition occurs.     

The Compressional Properties of Dextrose Monohydrate and Anhydrous Dextrose of Varying Water Contents

The effect of moisture on the compressional properties of anhydrous dextrose and dextrose monohydrate was examined. Relationships between moisture content and both tablet tensile strength and tablet toughness were evaluated. An increase in the moisture content of anhydrous dextrose produced a corresponding increase in both strength parameters up to the 8.9% moisture level, possibly due to a recrystallising effect. However any further increase in moisture content beyond this point produced a marked reduction in both tablet tensile strength and tablet toughness. For dextrose monohydrate, any increase in moisture content obtained by exposure to elevated humidities led to a reduction in both tensile strength and toughness.

The consolidation of both anhydrous dextrose and dextrose monohydrate was improved with increasing moisture content, presumably due to a lubrication effect, The yield forces and percentage porosity obtained under compression for anhydrous dextrose were observed to decrease with increasing moisture content up to a level of 9.20%.     

A sparekey to netware

The object of this article is to identify the risks that are run in the network and communications aspects of a client/server environment and thus help to define what security controls ought to be put place for these. However, before it is possible to do this we need to define what is meant by ‘Client/Server’ systems.     

Effects of preservation by gamma-irradiation on the nutritional quality of Australian fish

Gamma-irradiation preservation of two species of Australian marine fish (Black Bream and Redfish) resulted in no significant changes in their fatty-acid compositions, even when performed at up to three times the commonly recommended maximum dose for fish. Vitamin E loss was evident in some fillets but could not be correlated with the treatment dosage. All irradiated fillets were found to have vitamin E contents above the levels believed to be desirable for human consumption, relative to the amounts of accompanying polyunsaturated fatty acids.     

Minimizing Weighted Absolute Deviation in Single Machine Scheduling

This paper presents a procedure to minimize the total penalty when jobs are scheduled on a single machine subject to earliness and tardiness penalties. This performance criterion has been shown to be non-regular thus, requiring a search among schedules with inserted machine idle time to find a solution. A procedure to optimally insert idle time is also presented.     

The dynamics of articulated rigid bodies for purposes of animation

Curves and surfaces satisfying continuity and smoothness conditions are used in computer graphics to fit spatial data points. In a similar fashion, smooth motions of objects should be available to animators in such a way that the dynamics are correct to the degree required for realism. The motion, like a curve or surface shape, should be controllable by easy manipulations of a set of control parameters or by real-time interaction between the animator and a scene generated by dynamic simulation. In this paper, the objects considered have the form of rigid links joined at hinges to form a tree. This is a reasonable first approximation to human and animal bodies. The equations of motion are formulated with respect to hinge-centered coordinates, and are solved by an efficient technique in time which grows linearly with the number of links.