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991.
992.
Young people have much to offer urban planning, yet are not often included in such processes. A unique partnership in Boulder, Colorado, provides a venue for young people’s participation in city planning. Boulder is in many ways a learning laboratory with progressive ideals and sustainability thinking. As the city began planning for its Comprehensive Housing Strategy, tensions about the future of density within the city emerged. Participatory planning can have significant impacts on children and can also contribute new ideas to planning processes. In this study, young people demonstrated attitudinal changes toward government, increased recognition of diverse needs within a city, and integration of social and environmental sustainability into their recommendations for neighborhood planning. 相似文献
993.
994.
Shivy Victoria A.; Phillips Susan D.; Koehly Laura M. 《Canadian Metallurgical Quarterly》1996,43(2):178
Multidimensional scaling techniques (MDS) were used to examine the learning outcomes associated with J. L. Holland's Self-Directed Search (SDS; J. L. Holland, 1990). One hundred forty-six participants were randomly assigned to 3 conditions: the SDS, an attentional control, and a no treatment control. Based on the speculations of J. L. Holland, T. M. Magoon, and A. R. Spokane (1981), we hypothesized that participants who had completed the SDS would acquire Holland's complete RIASEC organizing scheme. No evidence of Holland's 2-dimensional RIASEC configuration was found for any of the groups. Examination of the 3-dimensional MDS solutions, however, suggested the presence of a prestige dimension and supported Holland's scheme as represented by D. J. Prediger's (1981) Things–People and Data–Ideas constructs. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
995.
Through telephone surveys, written questionnaires, and face-to-face interviews, it was found that people's biggest regrets tend to involve things they have failed to do in their lives. These divergent findings were reconciled by demonstrating that people's regrets follow a systematic time course: actions cause more pain in the short-term, but inactions are regretted more in the long run. Support for this contention was obtained in 2 scenario experiments that assessed people's beliefs about the short- and long-term regrets of others and in an experiment that asked Ss about their own regrets of action and inaction from 2 time periods. A total of 275 Ss participated in the experiments. Several mechanisms that can account for this temporal pattern are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
996.
Peptide Hydrogels—A Tissue Engineering Strategy for the Prevention of Oesophageal Strictures
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Deepak Kumar Victoria L. Workman Marie O'Brien Jane McLaren Lisa White Krish Ragunath Felicity Rose Alberto Saiani Julie E. Gough 《Advanced functional materials》2017,27(38)
Endoscopic treatment of Barrett's oesophagus often leads to further damage of healthy tissue causing fibrotic tissue formation termed as strictures. This study shows that synthetic, self‐assembling peptide hydrogels (PeptiGelDesign) support the activity and function of primary oesophageal cells, leading to epithelialization and stratification during in vitro 3D co‐culture. Following buffering in culture media, rat oesophageal stromal fibroblasts (rOSFs) are incorporated into a library of peptide hydrogels, whereas mouse oesophageal epithelial cells (mOECs) are seeded on the surface. Optimal hydrogels (PGD‐AlphaProC and PGD‐CGD2) support mOEC viability (>95%), typical cell morphology (cobblestone‐like), and slower migration over a shorter distance compared to a collagen control, at 48 h. Positive expression of typical epithelial markers (ZO‐1 and cytokeratins) is detected using immunocytochemistry at day 3 in culture. Furthermore, optimal hydrogels are identified which support rOSF viability (>95%) with homogeneous distribution when incorporated into the hydrogels and also promote the secretion of collagen type I detected using an enzyme linked immunosorbent assay (ELISA), at day 7. A 3D co‐culture model using optimal hydrogels for both cell types supports a stratified epithelial layer (expressing involucrin and AE1/AE3 markers). Findings from this study could lead to the use of peptide hydrogels as a minimally invasive endoscopic therapy to manage oesophageal strictures. 相似文献
997.
Effect of pH on the Binding of Sodium,Lysine, and Arginine Counterions to <Emphasis Type="SmallCaps">l</Emphasis>-Undecyl Leucinate Micelles
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Corbin Lewis Burgoyne H. Hughes Mariela Vasquez Alyssa M. Wall Victoria L. Northrup Tyler J. Witzleb Eugene J. Billiot Yayin Fang Fereshteh H. Billiot Kevin F. Morris 《Journal of surfactants and detergents》2016,19(6):1175-1188
Micelle formation by the amino acid-based surfactant undecylenyl l-leucine was investigated as a function of solution pH with NMR, dynamic light scattering, and fluorescence spectroscopy. NMR and dynamic light scattering showed that 50 mM undecylenyl l-leucine and 50 mM NaHCO3 solutions contained micelles approximately 20 Å in diameter and that micelle radius and the mole fraction of surfactant molecules associated with micelles changed very little with solution pH. The binding of the amino acids arginine and lysine to the anionic micelles was also investigated from pH 7.0 to 11.5. Below pH 9.0, the mole fraction of arginine cations bound to the micelles was approximately 0.4. Above pH 9.0, the arginine counterions became zwitterionic, and the mole fraction of bound arginine molecules decreased steadily to less than 0.1 at pH 11. When arginine dissociated from the micelles, their radii decreased from 14 to 10 Å. Similar behavior was observed with lysine; however, when lysine dissociated from the micelle surface, little change in micelle radius was observed. Two-dimensional NMR experiments suggested that below pH 9.0, l-arginine bound perpendicular to the micelle surface primarily though its side chain amine while l-lysine bound parallel to the surface through both of its amine functional groups. Finally, the rate at which the amide protons on the surfactant headgoup exchanged with solvent was investigated with NMR spectroscopy. The exchange reaction was faster in solutions containing only surfactant monomers and slower when the surfactants were in micellar form and the headgoup amide protons were less exposed to solvent. 相似文献
998.
Maria Atanassova Nikolay Vassilev Emil Tashev Victoria Lachkova Sabi Varbanov 《分离科学与技术》2016,51(1):49-56
The solvent extraction of trivalent lanthanoids (Ln3+) by 5,11,17,23-tetra(para-tert-octyl)-25,26,27,28-tetrakis(dimethylphosphinoylmethoxy)calix[4]arene (S), bearing four phosphine oxide donor groups at the lower rim as synergistic agent in combination with a 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one (HP) in CHCl3 from chloride medium at µ = 0.1 was quantitatively described in the form of LnP3·S complexes. The role of the synergistic agent on the extraction process was discussed. The values of the separation factors have been evaluated. On the basis of the IR and NMR spectra the stoichiometry and the structure of the solid mixed complex of Eu(III) with HP and S were proposed. 相似文献
999.
1000.
Rubn Núez Csar Domínguez Stephen Askins Marta Victoria Rebeca Herrero Ignacio Antn Gabriel Sala 《Progress in Photovoltaics: Research and Applications》2016,24(5):663-679
A methodology is presented to determine both the short‐term and the long‐term influence of the spectral variations on the performance of multi‐junction (MJ) solar cells and concentrator photovoltaic (CPV) modules. Component cells with the same optical behavior as MJ solar cells are used to characterize the spectrum. A set of parameters, namely spectral matching ratios (SMRs), is used to characterize spectrally a particular direct normal irradiance (DNI) by comparison to the reference spectrum (AM1.5D‐ASTM‐G173‐03). Furthermore, the spectrally corrected DNI for a given MJ solar cell technology is defined providing a way to estimate the losses associated to the spectral variations. The last section analyzes how the spectrum evolves throughout a year in a given place and the set of SMRs representative for that location are calculated. This information can be used to maximize the energy harvested by the MJ solar cell throughout the year. As an example, three years of data recorded in Madrid shows that losses lower than 5% are expected because of current mismatch for state‐of‐the‐art MJ solar cells. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献