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151.
Siegfried Skirl Ralph Krause Sheldon M. Wiederhorn Jürgen Rödel 《Journal of the American Ceramic Society》2001,84(9):2034-2040
Composites with microstructures of interpenetrating networks were manufactured by gas pressure infiltration of Ni3 Al into porous preforms of aluminum oxide. Composites with Ni3 Al contents of between 15% and 30% by volume were made and evaluated mechanically at temperatures between room temperature and 1000°C. The fracture strength, the fracture toughness, Young's modulus, and the thermal expansion coefficient were measured for each composite and test condition and were correlated with the microstructures of the composites. Composites with low Ni3 Al contents had strengths below 400 MPa, presumably due to microcracking along the interface between the Ni3 Al and the Al2 O3 . The composite with the highest content of Ni3 Al, 30 vol%, had a mean fracture strength of 675 ± 16 MPa, a Weibull modulus of 23.9, and a room-temperature toughness of 9.2 ± 0.5 MPa·m1/2 . 相似文献
152.
Validating smoking data from the Veteran's Affairs Health Factors dataset, an electronic data source
153.
Sheldon M. Widerhorn Edwin R. Fuller Jr. 《Journal of the American Ceramic Society》1989,72(2):248-251
Data on the growth of cracks tested in aqueous solutions were interpreted in terms of surface force theory. For applied stress intensity factors greater than 0.25 MPa · m½, the position and the slope of the curves and their dependence on pH and ion concentration can be explained in terms of surface force theory, provided these forces are of a magnitude and range that are representative of those involved in the cohensive bonding of solids. Weaker forces, such as structural, double-layer, or dispersion forces, have little effect on crack growth in silica glass for K I > 0.25 MPa · m½. 相似文献
154.
The effect of essential fatty acid (EFA) deficiency on rat-brain myelin proteins was studied. Rats were maintained on a lipid-free
diet and compared with control rats fed the same diet supplemented with 3% corn oil. At 17 days of age, each pup was injected
with [3H]leucine and rats from each group were killed over a period of 163 days. Although a large decrease occurred in the total
amount of myelin protein per brain, the proportions of constituent myelin proteins remained relatively unchanged. Metabolic
studies showed a decrease in the net turnover of myelin proteins analogous to that previously demonstrated for myelin phospholipid
(PL). 相似文献
155.
156.
Erectile dysfunction is a common (affecting 10-20 million men in the USA) and multifactorial disease due to organic and/or psychological factors that strongly impairs the quality of life in man. During the past decade many advances in the understanding of the pathophysiology of erectile dysfunction have been made and new therapeutic strategies have become available. It has been established that an insufficient production of nitric oxide by penile nerve terminals and/or vascular endothelium may result in an impaired erection or complete impotence. Nowadays, intracavernous injection of vasoactive drugs represents a standardized approach for the diagnosis, and the treatment of choice, for erectile dysfunction, but is not widely accepted by the patients. The possibility of treating erectile dysfunction with intraurethral administration of prostaglandin-E1 has recently become available in the USA, and is a therapy more acceptable to the patients. Other noninvasive medical therapies are undergoing evaluation. 相似文献
157.
Mohammad Z. Hossain Mohamad H. Kassaee Sheldon Jeter Amyn S. Teja 《International Journal of Thermophysics》2014,35(2):246-255
A new model based on rough hard-sphere theory is proposed for the thermal conductivity of molten salts. The model incorporates a smooth hard-sphere contribution using the properties of argon, as well as characteristic parameters based on the melting point of the molten salt. It is demonstrated that it is possible to correlate the thermal conductivity of monovalent and multivalent molten salts within experimental error using this approach. Furthermore, in salts with a common anion, the single adjustable parameter in the model exhibits regular behavior with the molecular weight of the salt. It is also shown that the thermal conductivity of several molten-salt mixtures can be predicted without any mixture parameters. 相似文献
158.
This paper presents the design and operational performance data of an anaerobic/aerobic hybrid side-stream Membrane Bioreactor (MBR) process for treating paper mill effluent operated over a 6 month period. The paper mill effluent stream was characterized by a chemical oxygen demand (COD) range of between 1,600 and 4,400 mg/L and an average BOD of 2,400 mg/L. Despite large fluctuations in COD feed concentration, stable process performance was achieved. The anaerobic Expanded Granular Sludge Bed (EGSB) pre-treatment step effectively lowered the organic loading by 65 to 85%, thus lowering the MBR COD feed concentration to consistently below 750 mg/L. The overall MBR COD removal was consistent at an average of 96%, regardless of the effluent COD or changes in the hydraulic retention time (HRT) and organic loading rate (OLR). Combining a high-rate anaerobic pre-treatment EGSB with a Modified Ludzack-Ettinger (MLE) MBR process configuration produced a high quality permeate. Preliminary NF and RO results indicated an overall COD removal of around 97 and 98%, respectively. 相似文献
159.
Sheldon M. Jeter 《Solar Energy》1986,37(5)
A first integral of the concentrated radiant flux density for trough concentrators is derived by exploiting the symmetry of these cylindrical systems. The resulting semifinite formulation yields both conceptual advantages and computational efficiency. The formulation is illustrated by application to the parabolic trough concentrator. The elementary example of determining the concentrated flux density at the nominal focal plane is first considered. The more realistic case of a round absorber tube, which can shade the reflector, centered on the focal line is also studied. This more practical geometry, which corresponds to most commercial designs, has previously received little attention in the open literature. These applications illustrate that the semifinite formulation presented herein can be a simple and useful tool for the analysis and design of trough concentrators. 相似文献
160.
Ki Su Kim Hyemin Kim Yunji Park Won Ho Kong Seung Woo Lee Sheldon J. J. Kwok Sei Kwang Hahn Seok Hyun Yun 《Advanced functional materials》2016,26(15):2512-2522
Vaccines are commonly administered by injection using needles. Although transdermal microneedles are less invasive promising alternatives, needle‐free topical vaccination without involving physical damage to the natural skin barrier is still sought after as it can further reduce needle‐induced anxiety and is simple to administer. However, this long‐standing goal has been elusive since the intact skin is impermeable to most macromolecules. Here, we show an efficient, noninvasive transdermal vaccination by employing two key innovations: the use of hyaluronan (HA) as vaccine carriers and non‐ablative laser adjuvants. Conjugates of a model vaccine ovalbumin (OVA) and HA—HA–OVA conjugates—induced more effective maturation of dendritic cells in vitro, compared to OVA. Following topical administration in the skin, HA–OVA conjugates penetrated into the epidermis and dermis in murine and porcine skins, as revealed by intravital microscopy and fluorescence assay. Topical administration of HA‐OVA conjugates significantly elevated both humoral and mucosal antibodies, with peak levels at four weeks. An OVA challenge at week eight elicited strong immune‐recall responses. With pretreatment of the skin using non‐ablative fractional laser beams as adjuvant, strong immunization was achieved with much reduced doses of HA–OVA (1 mg kg–1 OVA). Our results demonstrate the potential of the noninvasive patch‐type transdermal vaccination platform. 相似文献