Design, manufacture and evaluation of a scalable high-performanceneural system

The authors describe a scalable neural system, HyperNet, based on a probabilistic RAM-based architecture and using a custom VLSI IC. A system using five HyperNet VLSI ICs and capable of realising up to 10240 neurons has been designed, manufactured and demonstrated to have the potential to learn more than three orders of magnitude faster than simulations on current workstations     

Extrahepatic metabolism of 4-methylumbelliferone and lidocaine in the anhepatic rabbit

OBJECTIVE: The initially well-fixed implants of total hip replacement (THR) are in the long-term subject to aseptic loosening. Many cytokines can contribute to osteolysis due to osteoclast recruitment and/or activation. However, in this respect tumor necrosis factor-alpha (TNF-alpha) plays a pivotal role, because it upregulates interleukin-1 and 6 and granulocyte-macrophage colony stimulating factor. The aim of this study was to assess the eventual presence, cellular localization and extent of expression of TNF-alpha in the synovial-like membrane at the implant or at the cement to bone interface compared to control synovial membrane. METHODS: Twenty samples from the synovial-like membrane of the periprosthetic tissues were compared to control samples. TNF-alpha containing cells were visualized using an avidin-biotin-peroxidase complex (ABC) method and analyzed by light microscopy, double labelling and image analysis. RESULTS: TNF-alpha was found in the periprosthetic tissues in fibroblasts and vascular endothelial cells, but mainly in the macrophages was it found to coincide with areas containing implant-derived debris. TNF-alpha containing cells were more numerous in the synovial-like membrane in the interface tissue from the proximal stem area (2816 +/- 318 cells) than in the control synovial membrane (565 +/- 93 cells, p < 0.01). Interestingly, similarly high TNF-alpha expression (3452 +/- 582 cells) was also seen in the synovial-like membrane of the pseudocapsule. CONCLUSION: These findings suggest that the foreign body-type host reaction caused by THR is characterized by the high expression of TNF-alpha. Because such expression occurred in the interface tissue between the implant and surrounding bone, TNF-alpha, due to its pivotal direct and indirect role in the activation and recruitment of osteoclasts, may contribute to periprosthetic osteolysis and to the loosening of THR.     

Explicit finite difference scheme for nonlinear convective problems

An explicit finite difference scheme is proposed for nonlinear convective problems. The procedure is applied to a nonlinear convective diffusion problem with a nonlinear boundary condition. It is shown that the nonlinear boundary condition may be treated directly without linearization which has to be carried out in the implicit method to avoid a nonlinear system of algebraic equations. The explicit procedure is more direct and less cumbersome than the implicit procedure and the answers are in excellent agreement with those of the implicit method.     

Characterization of polymer‐layered silicate (clay) nanocomposites by transmission electron microscopy and X‐ray diffraction: A comparative study

Several polymer‐layered silicate (clay) nanocomposites (PLSNs) were analyzed by transmission electron microscopy (TEM) and wide‐angle X‐ray diffraction (XRD) in an effort to characterize the nanoscale dispersion of the layered silicate. The PLSNs investigated included thermoset (cyanate esters) and thermoplastic polymers (polystyrene, nylon 6, and polypropylene‐g‐maleic anhydride). The results of this study reveal that the overall nanoscale dispersion of the clay in the polymer is best described by TEM, especially when mixed morphologies are present. XRD is useful for the measurement of d‐spacings in intercalated systems but cannot always observe low clay loadings (<5%) or be used as a method to identify an exfoliated nanocomposite where no XRD peaks are present (constituting a negative result). Most importantly, the study showed that XRD is not a stand‐alone technique, and it should be used in conjunction with TEM. Our studies suggest that new definitions, or a clarification of existing definitions, are needed to properly describe the diversity of PLSN nanostructures seen in various materials. Published 2002 Wiley Periodicals, Inc. J Appl Polym Sci 87: 1329–1338, 2003     

量化网络风险

基本风险分析技术能帮助您从整个电力行业分布的角度了解工业控制系统和SCADA(数据采集与监控)系统中的网络威胁。这一步骤将帮助您规划一个防御性的策略。2006年8月19号,Brown' s Ferry核电站因为过程控制网络流量过大而堵塞,导致了再循环泵的损坏。操作员按照操作手册要求将其关闭,并将系统调整到安全状态。一份后续的美国核管理委员会(NRC)报告确定其根源为未确定来源的车间计算机网络通信量过大。由此采取了运     

Hemispherical concentrators and spectral filters for planar sensors in diffuse radiation fields

A dielectric hemisphere of refractive index N can act as an N(2) concentrator of isotropic diffuse radiation under appropriate conditions. We give an analytic expression for the gain of a concentrator of arbitrary radius, neglecting surface reflections, and numerical methods for calculating the gain when the surface transmissivity is an arbitrary function of incidence angle. The theory is applied to the design of multilayer spectral filters for hemispherical concentrators. When an appropriate wavelength shift is incorporated into the design process, an 11-layer, coupled-cavity spectral filter on the surface of a hemisphere of index 1.5 shows excellent bandpass performance with a concentrator radius as small as 3 times the sensor radius. This concentrator-filter combination shows a peak response of 97% of the ideal N(2) response at 950 nm, together with a FWHM of 55 nm.