机构输入与识别系统的研究——机构创新设计系统研究之三

介绍了机构创新设计系统以两种方式输入简图作为构型设计的原形。一种是在系统界面环境直接点击专用菜单绘制简图；一种方式是由设计者提供手绘草图或图纸，通过图像处理和模式识别技术，实现草图的获取，转化为系统机构绘制单元组成的简图。机构生成模块对简图可以进行自动识别纠错，保证机构的合理性，得到完整的机构信息。机构输入系统的实现，奠定了机构创新设计的自动化、智能化基础。     

Performance optimization of integrated gas and power within microgrids using hybrid PSO–PS algorithm

In this paper, a hybrid algorithm consisting of particle swarm optimization and pattern search algorithm is proposed to evaluate and optimize the design and operation of microgrids (MGs) in combined gas and power networks. Key performance indicators (KPIs) are modeled and proposed to evaluate and assess MGs. The paper begins by proposing a comprehensive study to define KPIs, which are used to evaluate the following MG parameters: economical efficiency, reliability, environmental conservation, and power quality. Multi‐objective evaluation functions are then developed by building a relationship matrix of MG and KPI components. The results are then displayed as optimized power generation percentages for each technology with values for four KPI categories: cost, quality, reliability and environmental friendliness. Two case studies are examined in this paper; both the province of Ontario and Toronto regional zone under all system parameters with varying percentage of generation via gas technology. Results indicated that the optimal scenario for both Ontario and Toronto was achieved at hybrid PSO–patern search percentage generation via gas technology with improved cost KPI and other KPIs remaining approximately constant. Copyright © 2016 John Wiley & Sons, Ltd.     

ZnO-Al_2O_3-B_2O_3-SiO_2系微晶玻璃与可伐合金的润湿性能

研制了一种新型的与可伐熔封的ZnO-Al_2O_3-B_2O_3-SiO_2系微晶玻璃,研究了不同工艺条件下微晶玻璃与可伐合金间的润湿角大小,结果表明,熔封气氛和熔封温度对润湿性能影响很大,熔封时间影响最小.采用最佳的工艺条件,其润湿性能与现有的其它玻璃润湿性能相似.同时发现玻璃与可伐合金间的润湿角保持在10°～30°之间能得到质量良好的熔封产品.在基本不改变传统工艺制度的条件下,可完成锌铝硼硅系微晶玻璃与可伐合金的熔封,即利用排蜡过程同时完成微晶玻璃的形核,熔封后在稍低温度保温或减慢冷却速度可以完成微晶玻璃的结晶过程.锌铝硼硅系微晶玻璃与预氧化可伐合金的封接依靠玻璃中的SiO_2与FeO或Fe_3O4发生界面反应形成牢固的结合.     

化学水浴沉积CdS薄膜晶相结构及性质

采用CBD法在醋酸镉溶液体系中制备CdS半导体薄膜，研究了溶液组份的浓度对CdS结晶结构的影响．增加乙酸胺的浓度、提高溶液的pH值有利于生成立方晶CdS，反之则易于生成六方晶CdS．无论立方相还是六方相CdS薄膜，电阻率均在10~4～10~5Ω·cm范围，结晶均匀细致．用六方晶为主和立方晶为主的CdS制备的CIGS太阳电池最高效率分别达到12.10%和12.17%．     

Resuspension of soil as a source of airborne lead near industrial facilities and highways

Geologic materials are an important source of airborne particulate matter less than 10 microm aerodynamic diameter (PM10), but the contribution of contaminated soil to concentrations of Pb and other trace elements in air has not been documented. To examine the potential significance of this mechanism, surface soil samples with a range of bulk soil Pb concentrations were obtained near five industrial facilities and along roadsides and were resuspended in a specially designed laboratory chamber. The concentration of Pb and other trace elements was measured in the bulk soil, in soil size fractions, and in PM10 generated during resuspension of soils and fractions. Average yields of PM10 from dry soils ranged from 0.169 to 0.869 mg of PM10/g of soil. Yields declined approximately linearly with increasing geometric mean particle size of the bulk soil. The resulting PM10 had average Pb concentrations as high as 2283 mg/kg for samples from a secondary Pb smelter. Pb was enriched in PM10 by 5.36-88.7 times as compared with uncontaminated California soils. Total production of PM10 bound Pb from the soil samples varied between 0.012 and 1.2 mg of Pb/kg of bulk soil. During a relatively large erosion event, a contaminated site might contribute approximately 300 ng/m3 of PM10-bound Pb to air. Contribution of soil from contaminated sites to airborne element balances thus deserves consideration when constructing receptor models for source apportionment or attempting to control airborne Pb emissions.     

Beta3 receptors mediate relaxation in stomach fundus whereas a fourth beta receptor mediates tachycardia in atria from transgenic beta3 receptor knockout mice

Pharmacological studies have revealed a non-beta1, beta2 or beta3 adrenergic receptor that mediates tachycardia in rat and human atria. The present studies utilized transgenic mice that lack the rodent beta3 receptor to explore, in a more definitive fashion, whether a non-beta1, beta2 or beta3 receptor can mediate atrial tachycardia. Insofar as the rat stomach fundus possesses a beta3 receptor mediating relaxation, we examined the stomach fundus from beta3 receptor knockout mice for the presence or absence of the beta3 relaxant receptor. Contractile responses to carbamylcholine were similar in potency and magnitude between mouse stomach fundus from wild type and beta3 receptor knockout animals. However, the classical beta3 receptor agonist CL316243, (10(-8)-10(-6)M) relaxed stomach fundus from wild type mice, but not from the beta3 receptor knockout animals. These data provide functional evidence for the absence of the beta3 receptor in beta3 receptor knockout animals and support the role of beta3 receptors mediating relaxation in mouse stomach fundus. Atria from mice lacking the beta3 receptor responded similarly (in potency and maximal increase in heart rate) to isoproterenol (10(-9)-10(-6)M) as atria from wild type mice. Furthermore, propranolol (3 x 10(-7) M) produced a dextral shift in the concentration response to isoproterenol in atria from both the beta3 receptor knockout and wild type mice with negative log K(B) values of 8.03 and 8.09, respectively. Thus, beta receptors mediating tachycardia to isoproterenol are intact and respond similarly in atria from both knockout and wild type mice. Furthermore, CGP12177, a prototypic 'atypical' beta receptor agonist produced tachycardia with a similar EC50 and maximal response in atria from both the wild type and beta3 receptor knockout mice. Cyanopindolol was a partial agonist relative to CGP12177 in both wild type and beta3 receptor knockout mice. Tachycardia to CGP12177 and cyanopindolol was not blocked by propranolol (3 x 10(-7) M) in atria from either group. These data provide definitive evidence that the receptor mediating tachycardia to CGP12177 and to cyanopindolol in atria from the transgenic beta3 receptor knockout mice is neither the beta1, beta2, nor beta3 adrenergic receptor.     

Icons improve older and younger adults' comprehension of medication information

We examined whether timeline icons improved older and younger adults' comprehension of medication information. In Experiment 1, comprehension of instructions with the icon (icon/text format) and without the icon (text-only format) was assessed by questions about information that was (a) implicit in the text but depicted explicitly by the icon (total dose in a 24 hour period), (b) stated and depicted in the icon/text condition (medication dose and times), and (c) stated but not depicted by the icon (e.g., side effects). In a separate task, participants also recalled medication instructions (with or without the icon) after a study period. We found that questions about dose and time information were answered more quickly and accurately when the icon was present in the instructions. Notably, icon benefits were greater for information that was implicit rather than stated in the text. This finding suggests that icons can improve older and younger adults' comprehension by reducing the need to draw some inferences. The icon also reduced effective study time (study time per item recalled). In Experiment 2, icon benefits did not occur for a less integrated version of the timeline icon that, like the text, required participants to integrate dose and time information in order to identify the total daily dose. The integrated version of the icon again improved comprehension, as in Experiment 1, as well as drawing inferences from memory. These findings show that integrated timeline icons improved comprehension primarily by aiding the integration of dose and time information. These findings are discussed in terms of a situation model approach to comprehension.     

Definition of natural T cell antigens with mimicry epitopes obtained from dedicated synthetic peptide libraries

Progress has recently been made in the use of synthetic peptide libraries for the identification of T cell-stimulating ligands. T cell epitopes identified from synthetic libraries are mimics of natural epitopes. Here we show how the mimicry epitopes obtained from synthetic peptide libraries enable unambiguous identification of natural T cell Ags. Synthetic peptide libraries were screened with Mycobacterium tuberculosis-reactive and -autoreactive T cell clones. In two cases, database homology searches with mimicry epitopes isolated from a dedicated synthetic peptide library allowed immediate identification of the natural antigenic protein. In two other cases, an amino acid pattern that reflected the epitope requirements of the T cell was determined by substitution and omission mixture analysis. Subsequently, the natural Ag was identified from databases using this refined pattern. This approach opens new perspectives for rapid and reliable Ag definition, representing a feasible alternative to the biochemical and genetic approaches described thus far.