The effects of multifocal refractive lenses on occipital extension and forward head posture during a visual task

The purpose of this study was to determine if a change in forward head posture and occipital extension occurred in participants who wore multifocal lenses vs. those persons with non-multifocal lenses while performing an 8-min visual reading task on a visual display unit (VDU). Forty-two healthy human participants were recruited for this study. Thirty-three participants completed the study. Fourteen participants wore multifocal lenses and 19 wore frames with non-multifocal lenses. To evaluate the degree of change of forward head posture and occipital extension digital photographs of cervical posture were taken at four different time intervals: prior to performing the reading task and at 3, 5 and 8 min during the reading task. The digital photographs were analysed utilizing a computer program. Two one-way ANOVA were utilized to determine the degree of change of forward head posture and occipital extension between groups. A significant difference was identified between groups for changes in degrees of forward head posture while performing a visual reading task on a VDU. However, no significant difference between groups was found for occipital extension while performing the same task. Multifocal wearers exhibit greater degrees of change in forward head posture and occipital extension than non-multifocal wearers. These postural changes may place them at a greater risk for musculoskeletal disorders and headaches.     

Virtual rheoscopic fluids for flow visualization

Physics-based flow visualization techniques seek to mimic laboratory flow visualization methods with virtual analogues. In this work we describe the rendering of a virtual rheoscopic fluid to produce images with results strikingly similar to laboratory experiments with real-world rheoscopic fluids using products such as Kalliroscope. These fluid additives consist of microscopic, anisotropic particles which, when suspended in the flow, align with both the flow velocity and the local shear to produce high-quality depictions of complex flow structures. Our virtual rheoscopic fluid is produced by defining a closed-form formula for the orientation of shear layers in the flow and using this orientation to volume render the flow as a material with anisotropic reflectance and transparency. Examples are presented for natural convection, thermocapillary convection, and Taylor-Couette flow simulations. The latter agree well with photographs of experimental results of Taylor-Couette flows from the literature.     

Promoting positive relations between parents and child--a counseling service for families with infants and young children in Sydney

The "Early Intervention Programme" (EIP) in Sydney, Australia, is a home-based service for distressed families with children 0-3 years of age. It is funded as a child abuse prevention unit. The concept is based on the work of Selma Fraiberg (1980), who developed the first infant mental health program in Michigan, USA. The goal of the EIP is to strengthen the relationship between parents and child through developmental guidance, psychotherapy and/or provision of active help. The child is seen as an important partner in the intervention process.     

Monomers of human beta 1 beta 1 alcohol dehydrogenase exhibit activity that differs from the dimer

A previously unreported enzymatic activity is described for monomers of the beta 1 beta 1 isoenzyme of human alcohol dehydrogenase that were prepared from dimeric enzyme by freeze-thaw in liquid nitrogen. Whereas the dimeric enzyme has optimal activity at low substrate concentrations (2.5 mM ethanol, 50 microM NAD+; "low Km" activity), the monomer has its highest activity at high substrate concentrations (1.5 M ethanol, 2.5 mM NAD+; "high Km" activity). While the activity of the monomer does not appear to be saturated at 1.5 M ethanol, its maximal activity at this high ethanol concentration exceeds the Vmax of the dimer by about 3-fold. The apparent Km of NAD+ with monomers is 270 microM, and no activity could be detected with nicotinamide mononucleotide as cofactor. During gel filtration the high Km activity elutes at a lower apparent molecular weight position than the dimer. The kinetics of monomer-to-dimer reassociation are consistent with a second-order process with a rate constant of 240 M-1 s-1. The reassociation rate is markedly enhanced by the presence of NAD+. During refolding of beta 1 beta 1 following denaturation in 6 M guanidine hydrochloride, an enzyme species with high Km activity and spectral properties similar to the freeze-thaw monomer is observed, indicating that a catalytically active monomer is an intermediate in the refolding pathway. The enzymatic activity of the monomer implies that the intersubunit contacts of beta 1 beta 1 are not crucial in establishing a catalytically competent enzyme. However, the differences in specific activity and Km between monomer and dimer suggest that dimerization may serve to modulate the catalytic properties.     

Habituation of the orienting response: a gating mechanism subserving selective attention

Possibilities of involution of changes in lesser circulation after closure of experimental aortopulmonary anastomosis were studied. 37 observations at various intervals after closure of anastomosis (several minutes to 13.5 months) in 25 dogs were analyzed. Before closure the anastomosis had functioned for 1-7 months. The results of histological examinations of lungs, pressure measurements in lesser circulation, heart weight, electrocardiographic and spirographic examinations were analyzed. It was found that complete involution of changes in lesser circulation was possible only in first month of existence of anastomosis, in this case with changes of both "early" and "late" types. "Late"-type changes after four months function of anastomosis had both reversible and irreversible character, whereas "early"-type changes became irreversible already after three-month duration of anastomosis. With the "late"-type changes, the operation itself (closure of anastomosis) was accompanied by symptoms of pulmonary vasomotor paresis and heart failure, whereas in the presence of "early"-type changes the operation elicited no morphological or functional changes.     

Intercomparison of Thermophysical Property Measurements on an Austenitic Stainless Steel

The results of an inter laboratory comparison of thermal conductivity, thermal diffusivity, specific heat capacity, and thermal expansion measurements on austenitic stainless steel in the temperature range between 20 and 1000°C are presented here. Mean values are presented for the physical properties studied. Reliable relative expanded uncertainties can be stated for the properties determined, which were achieved by applying good measurement practice, i.e., 3% for thermal expansion, 5% for specific heat capacity and thermal diffusivity, and 6% for thermal conductivity. The mean values derived from this intercomparison agree well with the results of a previous intercomparison in 1990. An erratum to this article is availabale at .     

pH influences hydrolysis of sodium polyphosphate in dairy matrices and the structure of processed cheese

We investigated the effect of pH (5.2 to 6.8) on the hydrolysis of a sodium polyphosphate in water, milk, calcium caseinate, and spreadable processed cheese, as well as the effect of pH on the cheese structure. Monitoring of the hydrolysis in water and the different milk matrices was carried out using ³¹P nuclear magnetic resonance technique. In general, the decrease in pH increased the hydrolysis of polyphosphates in all matrices. The presence of calcium in milk increased the rate of hydrolysis. Hydrolysis in milk was higher than in calcium caseinate, probably due to lower molecular mobility in concentrated systems with high viscosity. Increasing the pH decreased the hardness and adhesiveness of the cheeses. At low pH (5.2 and 5.6), the cheeses presented a granular structure, although, at more neutral pH (6.0 to 6.8), the structure was continuous, homogeneous, and more fluid. These results highlight the importance of precise pH control in the manufacture of processed cheeses.     

Quantifizierungen von Grundwassereintritten in städtische Abwassersysteme mittels stabiler Isotope

Infiltration of groundwater into sewer systems increases the costs for wastewater treatment plant operators. This study explores groundwater infiltration to urban sewer systems in the city of Nuremberg (Germany). Measurements of stable isotopes at the water works, storage tanks, groundwater, and the sewage network were carried out to define input end members for mass balance calculations. Only minor differences in oxygen stable isotopes (δ¹⁸O_H2O) were found between most sewer and drinking water samples which ranged around (??9.5?±?0.1) ‰. One exception was water from a water works at Genderkingen that is situated about 80 km south of Nuremberg. Here, drinking water from bank filtrate of the Lech River had more negative δ¹⁸O_H2O values of ??11.4?‰. This difference of 1.5?‰ revealed maximum possible groundwater contributions of 41?% by mass balance calculations. To obtain more accurate results, we suggest testing the use of deuterium-enriched water (D₂O) added to the sewer system.     

Solubility of Natural Gas in Diesel Fuel

The solubility of commercially available natural gas in commercially available diesel fuel at room temperature and defined pressure is investigated experimentally. The gas phase is considered to be pure methane. The use of Henry's law to model the solubility is discussed. Solubility is given in terms of the mole fraction and the volumetric mass concentration of dissolved gas and the corresponding Henry's coefficients. The solubility is compared to that of pure methane in pure hexadecane, which is similar to diesel fuel with respect to the mean carbon number.     

Fabrication and in situ characterization of microcapsules in a microfluidic system

We have designed a microfluidic system that enables both the fabrication of calibrated capsules and the in situ characterization of their mechanical properties. The fabrication setup consists of a double flow-focusing system. A human serum albumin aqueous solution is introduced in the central channel of a first Y-junction. Intercepted by the lateral flows of a hydrophobic phase, it is dispersed into microdroplets. A cross-linking agent is then introduced at a second Y-junction allowing a membrane to form around the droplets. The time of cross-linking is controlled by the length of a wavy channel located downstream of the second junction. A cylindrical microchannel finally enables to deform and characterize the capsules thus formed. The mechanical properties of the capsule membrane are obtained by inverse analysis. The results show that the drop size increases with the flow rate ratio between the central and lateral channels. The mean shear modulus of the capsules fabricated after 23 s of cross-linking is of the order of the surface tension between the two phases indicating that a reaction time of 23 s is too short for an elastic membrane to form around the droplet. When the cross-linking time is increased to 60 s, the microcapsules surface is wrinkled, thus confirming that a solid membrane is formed around the drop. The mean shear modulus of the capsule membrane increases with the cross-linking time, which is in agreement with our previous chemical results and proves that a fine control of the mechanical properties is possible by choosing adequately the control parameters of the system.