Second law analysis of a natural gas‐fired gas turbine cogeneration system

The influence of operating conditions such as reheat, intercooling, ambient temperature and pressure ratio are analyzed from a second law perspective on the performance of a natural gas‐fired gas turbine cogeneration system. The effect of these operating parameters on carbon dioxide emissions is also discussed. The second law efficiency of gas turbine cogeneration system increases markedly with reheat option. Higher pressure ratios lead to decreased second law cogeneration efficiency but this effect can be reduced with a higher level of reheat option. The effect of intercooling on second law efficiency is strongly related to pressure ratio with higher pressure ratios significantly decreasing efficiency. The second law efficiency is not so sensitive to the environment temperature for levels of reheat or intercooling greater than 50%. Copyright © 2009 John Wiley & Sons, Ltd.     

条顿骑士团的豹

德国豹2系列主战坦克凭借成功的设计、先进的制造工艺和出色的性能,自服役以来一直广受好评,并且被北约各成员国陆军广泛采用。车族中最新的量产型,造价高连850万德国马克的豹2A5KWS 更是集合了包括装甲防护,车截武器火控,电子抗干扰,卫星定位在内的各种高新技术于一身,被誉为当代最为先进,可靠的主战坦克。在各类战车评试演习中均取得了良好的成绩。成为有意采购新型坦克各国的首选车型之一。而豹2A6型将装备 L55/120mm 滑膛炮和尚处于试验阶段的 140mm 坦克炮,宣称可以满足未来20年内 C41时代苛刻的战场要求。     

The Well Mannered Wearable Computer

In this paper we describe continuing work being carried out as part of the Bristol Wearable Computing Initiative. We are interested in the use of context sensors to improve the usefulness of wearable computers. A CyberJacket incorporating a Tourist Guide application has been built, and we have experimented with location and movement sensing devices to improve its performance. In particular, we have researched processing techniques for data from accelerometers which enable the wearable computer to determine the user’s activity. We have experimented with, and review, techniques already employed by others; and then propose new methods for analysing the data delivered by these devices. We try to minimise the number of devices needed, and use a single X-Y accelerometer device. Using our techniques we have adapted our CyberJacket and Tourist Guide to include a multimedia presentation which gives the user information using different media depending on the user’s activity as well as location.     

An Introduction to the Community of Professors: The Engineering Education Scholars Workshop

It can be difficult for new faculty to get the information they need on issues such as teaching, advising, and setting up a research program. While some have excellent mentors, others have come to rely on trial and error or word of mouth. In 1996, the NSF Engineering Education Scholars Workshop began at Carnegie Mellon University to address the needs of new and future engineering faculty by:

• ? providing professional teaching development;
• ? offering guidance in supervising graduate students and conducting research;
• ? discussing likely engineering education and research challenges in the 21^st century; and
• ? providing intellectual and social support with colleagues.

After three years, a significant amount of knowledge and experience has been gathered by the workshop co‐chairs. This paper details the structure of the workshop and discusses the underlying principles and implementation to provide guidance for those planning similar workshops.     

Proteolytic cleavage and activation of PAK2 during UV irradiation-induced apoptosis in A431 cells

Exposure of mammalian cells to ultraviolet (UV) light elicits a cellular response and can also lead to apoptotic cell death. In this report, we show that a 36-kDa myelin basic protein (MBP) kinase detected by an in-gel kinase assay can be dramatically activated during the early stages of UV irradiation-triggered apoptosis of A431 cells. Immunoblot analysis revealed that this 36-kDa MBP kinase could be recognized by an antibody against the C-terminal regions of a family of p21Cdc42/Rac-activated kinases (PAKs). By using this antibody and a PAK2-specific antibody against the N-terminal region of PAK2 as studying tools, we further demonstrated that UV irradiation caused cleavage of PAK2 to generate a 36-kDa C-terminal catalytic fragment and a 30-kDa N-terminal fragment in A431 cells. The appearance of the 36-kDa C-terminal catalytic fragment of PAK2 matched exactly with the activation of the 36-kDa MBP kinase in A431 cells upon UV irradiation. In addition, UV irradiation also led to activation of CPP32/caspase-3, but not ICH-1L/caspase-2 and ICE/caspase-1, in A431 cells and the kinetics of activation of CPP32/caspase-3 appeared to correlate well with that of DNA fragmentation and of cleavage/activation of PAK2, respectively. Moreover, blockage of activation of CPP32/caspase-3 by pretreating the cells with two specific tetrapeptidic inhibitors for caspases (Ac-DEVD-cho and Ac-YVAD-cmk) could significantly attenuate the extent of cleavage/activation of PAK2 induced by UV irradiation. Collectively, the results demonstrate that cleavage and activation of PAK2 can be induced during the early stages of UV irradiation-triggered apoptosis and indicate the involvement of CPP32/caspase-3 in this process.     

Reducing pregnancy and induced abortion rates in China: family planning with husband participation

OBJECTIVES: This study assessed the effectiveness of a family planning intervention with and without husband's participation in reducing pregnancy and abortion rates in Shanghai, China. METHODS: In this 3-arm randomized trial among 1800 nonsterilized married women, educational interventions targeting both spouses and targeting the wife only were compared with usual family planning care. RESULTS: Among women not using intrauterine devices (IUDs), the intervention with husband's participation had an effect in reducing pregnancy rates (adjusted odds ratio [OR] = 0.36, 95% confidence interval [CI] = 0.12, 1.1) and abortion rates (adjusted OR = 0.29, CI = 0.09, 0.94) compared with control subjects, and a significant effect in reducing pregnancy rates (adjusted OR = 0.29, CI = 0.10, 0.85) and abortion rates (adjusted OR = 0.24, CI = 0.07, 0.77) compared with wife-only subjects. CONCLUSIONS: Family planning interventions involving husbands may reduce pregnancy and abortion rates among non-IUD users.     

Induction of neutralizing antibody in mice by immunization with recombinant 56 kDa protein of Orientia tsutsugamushi

Anti-oriential antibody inhibits Orientia tsutsugamushi attachment to, and penetration of, host cells. However, O. tsutsugamushi antigens that induce the production of a neutralizing antibody have not been identified. The authors immunized mice and rabbits with the recombinant 56 kDa protein of O. tsutsugamushi fused to the maltose binding protein of Escherichia coli (MBP-Bor56) and analysed their effect on O. tsutsugamushi attachment to or penetration of L929 cells. O. tsutsugamushi attachment and penetration were measured by using an indirect immunofluorescent antibody assay (IFA). O. tsutsugamushi growth in L929 cells was determined by [3H]thymidine uptake assay. By IFA, we observed a 96% reduction of attachment or penetration of O. tsutsugamushi treated with rabbit anti-MBP-Bor56 sera. [3H]thymidine uptake showed that mouse anti-MBP-Bor56 sera caused a 91% reduction in O. tsutsugamushi growth, when compared to mouse anti-MBP sera. These results suggest that the 56 kDa protein of O. tsutsugamushi plays an important role in O. tsutsugamushi attachment to or penetration of cells.     

The history of research on blood group genetics: initial discovery and diffusion

During the 1920s and 1930s the resting of blood groups for large numbers of people became a very common practice. Although much of this was to ensure compatibility for blood transfusion, over 1,000 articles were published with results of tests on over 1.3 million people to answer more theoretical, scientific questions. The motivation for much of this research was the possible link between the well established hereditary blood types and other possible inherited traits. Because the existence of the blood groups was a rather sudden discovery, the record of this publication offers an excellent case study of the diffusion of new scientific knowledge. Differences in the beginning of blood group research from country to country reveal some important influences of social setting on the spread and application of the new discoveries.