全文获取类型
收费全文 | 2329篇 |
免费 | 5篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 1篇 |
化学工业 | 15篇 |
金属工艺 | 5篇 |
机械仪表 | 3篇 |
建筑科学 | 1篇 |
矿业工程 | 1篇 |
能源动力 | 3篇 |
轻工业 | 3篇 |
水利工程 | 1篇 |
无线电 | 20篇 |
一般工业技术 | 23篇 |
冶金工业 | 2257篇 |
自动化技术 | 2篇 |
出版年
2023年 | 3篇 |
2022年 | 2篇 |
2020年 | 3篇 |
2019年 | 1篇 |
2018年 | 2篇 |
2016年 | 4篇 |
2015年 | 1篇 |
2014年 | 3篇 |
2013年 | 11篇 |
2012年 | 5篇 |
2011年 | 3篇 |
2010年 | 2篇 |
2009年 | 3篇 |
2008年 | 1篇 |
2007年 | 3篇 |
2006年 | 8篇 |
2003年 | 5篇 |
2001年 | 1篇 |
2000年 | 4篇 |
1999年 | 70篇 |
1998年 | 741篇 |
1997年 | 373篇 |
1996年 | 273篇 |
1995年 | 132篇 |
1994年 | 112篇 |
1993年 | 121篇 |
1992年 | 19篇 |
1991年 | 29篇 |
1990年 | 19篇 |
1989年 | 22篇 |
1988年 | 21篇 |
1987年 | 23篇 |
1986年 | 16篇 |
1985年 | 17篇 |
1983年 | 3篇 |
1982年 | 12篇 |
1981年 | 12篇 |
1980年 | 17篇 |
1979年 | 1篇 |
1978年 | 3篇 |
1977年 | 67篇 |
1976年 | 161篇 |
1975年 | 3篇 |
1964年 | 1篇 |
1955年 | 2篇 |
排序方式: 共有2335条查询结果,搜索用时 15 毫秒
991.
PW Hermans SK Saha WJ van Leeuwen HA Verbrugh A van Belkum WH Goessens 《Canadian Metallurgical Quarterly》1996,34(6):1373-1379
Seventy-eight Salmonella typhi strains isolated in 1994 and 1995 from patients living in Dhaka, Bangladesh, were subjected to phage typing, ribotyping, IS200 fingerprinting, and PCR fingerprinting. The collection displayed a high degree of genetic homogeneity, because restricted numbers of phage types and DNA fingerprints were observed. A significant number of the S. typhi strains (67%) were demonstrated to be multiple drug resistant (MDR). The vast majority of the MDR strains were resistant to chloramphenicol, ampicillin, trimethoprim, streptomycin, sulfamethoxazole, and tetracycline (R type CATmSSuT), a resistance phenotype that has also frequently been observed in India. Only two strains displayed a distinct MDR phenotype, R type AT-mSSuT. Pulsed-field gel electrophoresis demonstrated the presence of large plasmids exclusively in the MDR strains of both R types. The plasmids present in the S. typhi strains of R type CATmSSuT could be conjugated to Escherichia coli and resulted in the complete transfer of the MDR phenotype. PCR fingerprinting allowed discrimination of MDR and susceptible strains. The DNA fragments enabling discrimination of MDR and susceptible S. typhi strains by PCR were useful genetic markers for identifying MDR encoded by large plasmids of the H1 incompatibility group. 相似文献
992.
993.
JW Barnard AF Seibert VR Prasad DA Smart SJ Strada AE Taylor WJ Thompson 《Canadian Metallurgical Quarterly》1994,77(2):774-781
Isoproterenol (ISO) and forskolin, agents that increase adenosine 3',5'-cyclic monophosphate (cAMP) via adenylyl cyclase activation, reverse lung injury associated with increased microvascular permeability. We studied the role of rolipram, a relatively isozyme-selective cAMP phosphodiesterase (PDE) inhibitor, in reversing increased capillary permeability due to ischemia-reperfusion (I/R), a form of oxidant injury in the lung, by using the isolated perfused rat lung model. Rolipram (2 microM) administered after 45 min of ischemia and 45 min of reperfusion reduced I/R-increased permeability as measured by the capillary filtration coefficient to control lung values. Computer image analysis of air space edema and perivascular cuffing, as well as wet-to-dry weight ratios, confirms the permeability reversal by rolipram administration. Rolipram inhibition of cAMP PDE in the lung was assessed by using [3H]adenine prelabeling adapted for the whole lung and perfusate [3H]cAMP accumulation. Rolipram failed to increase perfusate cAMP alone but dramatically increased perfusate cAMP above ISO alone. Dose-response relationships of ISO or rolipram show a close correlation of the half-maximal effective dose (ED50) for injury reversal and perfusate cAMP production. The combination of rolipram and ISO produced synergistic reversal of I/R injury. We conclude that reversal of I/R-induced increased microvascular permeability can be achieved with rolipram and that the mechanism of action of rolipram is probably through PDE isozyme-selective inhibition. The similarity of the ED50 values for cAMP efflux and reversal of permeability increases also supports a close coupling between cAMP accumulation and endothelial cell permeability. 相似文献
994.
In the Diego blood group, the frequency of the Di(a + b +) or Di(a + b -) phenotype among Chinese in Taiwan is estimated to be 3.2%. Here we report a case of severe hemolytic disease caused by anti-Di(a). The baby's total bilirubin elevated to 23 mg/dl at the age of 72 hours. A blood exchange transfusion and phototherapy were performed. We suggest to include Diego positive cell panels in testing antibody specificities that are likely to be encountered in this population. 相似文献
995.
996.
Experiments examined how learning processes modulate tolerance to discriminative stimulus effects of morphine. Rats were trained to discriminate saline and 3.2 mg/kg morphine, and the doses of morphine required to mimic the training dose were determined before, during and after repeated treatment with saline or high doses of morphine (10 mg/kg, b.i.d.). In one set of experiments, training was either suspended or continued with saline and the original training dose during a 2-week treatment regimen. When training was suspended, high-dose morphine treatment increased the dose of morphine required for stimulus effects approximately 3-fold. Tolerance persisted 2 days after treatment ended, but disappeared within 7 days. In contrast, continued training with saline and 3.2 mg/kg morphine during high-dose treatment both attenuated development of tolerance and transferred control to lower doses. Transfer of control to lower doses appeared conditional upon recent termination of high-dose treatment, as it disappeared within 7 days. Treatment with saline did not change the doses of morphine required for stimulus effects under either training condition. A final experiment examined whether high-dose treatment could transfer control to higher doses of morphine. The treatment dose of 10 mg/kg morphine itself was used as the training dose during a 2-week treatment regimen. The dose of morphine required for stimulus effects increased 2- to 4-fold during treatment, but quickly returned to control values when treatment ended. These results extend previous findings that conditioning and pharmacodynamic processes jointly regulate development of tolerance to discriminative effects of morphine. 相似文献
997.
998.
R Abegg M Ahmad D Bandyopadhyay J Birchall EB Cairns K Chantziantoniou GH Coombes CA Davis NE Davison PP Delheij PW Green LG Greeniaus HP Gubler DC Healey C Lapointe WP Lee WJ McDonald CA Miller GA Moss SA Page GR Plattner PR Poffenberger WD Ramsay NL Rodning G Roy J Soukup JP Svenne RR Tkachuk van Oers WT GD Wait JW Watson Y Ye YP Zhang 《Canadian Metallurgical Quarterly》1989,40(5):2406-2409
999.
Renal blood flow (RBF) was measured with a noncannulating electromagnetic flow transducer in anesthetized rats which had been maintained for 3-5 wk on low, normal, or high salt plus deoxycorticosterone diets. After base-line observations, one of two dissimilar inhibitors of the renin-angiotensin system, angiotensin I converting enzyme inhibitor SQ 20881 or the structural analogue [Sar1,Ala8]angiotensin II was administered intravenously. The employed doses of SQ 20881 and [Sar1,Ala8]angiotensin II effectively inhibited the pressor and renal vasoconstrictor responses induced by exogenous angiotensin I and II, respectively, in each dietary group. Both inhibitors vasodilated kidneys in salt-restricted rats; however, neither affected base-line renal hemodynamics in salt-loaded rats. Pressure-flow relationships were evaluated by clamping the aorta to reduce renal perfusion pressure. Renal blood flow was autoregulated between 100 and 140 mmHg with the same efficiency before and during inhibition of angiotensin II in each dietary group. These data indicate that angiotensin II modifies base-line RBF and renal vascular resistance and are consistent with the view that the renin-angiotensin system is not an essential mechanism responsible for autoregulation of RBF in the rat. 相似文献
1000.
NE Reich FE Seidelmann RR Tubbs WJ Mac Intyre TF Meaney RJ Alfidi RG Pepe 《Canadian Metallurgical Quarterly》1976,127(4):593-594
The usefulness and accuracy of CT scanning in the determination of bone mineral content is studied. The radius in 31 patients of both sexes and varying ages was examined using both the Norland-Cameron bone mineral analyzer and the CT scanner. There was reasonably good correlation (r=.72). Ten cadaver bones were then examined with CT scanning and were sent to the laboratory for calcium determination. These results indicate excellent correlation (r=.97). It is concluded that CT scanning represents the only practical and accurate in vivo method of bone mineral content determination. 相似文献