The stochastic -hub center problem with service-level constraints

Small package delivery companies offer services where packages are guaranteed to be delivered within a given time-frame. With variability in travel time, the configuration on the hub-and-spoke delivery network is vital in ensuring a high probability of meeting the service-level guarantee. We present the stochastic p-hub center problem with chance constraints, which we use to model the service-level guarantees. We discuss analytical results, propose solution heuristics, and present the results from computational experiments.     

A Multi‐Autonomous Underwater Vehicle System for Autonomous Tracking of Marine Life

This paper presents a multi‐autonomous underwater vehicle system capable of cooperatively and autonomously tracking and following marine targets (i.e., fish) tagged with an acoustic transmitter. The AUVs have been equipped with stereo‐hydrophones that receive signals broadcasted by the acoustic transmitter tags to enable real‐time calculation of bearing‐to‐tag and distance‐to‐tag measurements. These measurements are shared between AUVs via acoustic modem and fused within each AUV's particle filter for estimating the target's position. The AUVs use a leader/follower multi‐AUV control system to enable the AUVs to drive toward the estimated target state by following collision‐free paths. Once within the local area of the target, the AUVs circumnavigate the target state until it moves to another area. The system builds on previous work by incorporating a new SmartTag package that can be attached to an individual's dorsal fin. The SmartTag houses a full inertial measurement unit (INU), video logger, acoustic transmitter, and timed release mechanism. After real‐time AUV tracking experiments, the SmartTag is recovered. Logged IMU data are fused with logged AUV‐obtained acoustic tag measurements within a particle filter to improve state estimation accuracy. This improvement is validated through a series of multi‐AUV shark and boat tracking experiments conducted at Santa Catalina Island, California. When compared with previous work that did not use the SmartTag package, results demonstrated a decrease in mean position estimation error of 25–75%, tag orientation estimation errors dropped from 80° to 30° , the sensitivity of mean position error with respect to distance to the tag was less by a factor of 50, and the sensitivity of mean position error with respect to acoustic signal reception frequency to the tag was 25 times less. These statistics demonstrate a large improvement in the system's robustness when the SmartTag package is used.     

Comparison of technetium-99m-ECD to Xenon-133 SPECT in normal controls and in patients with mild to moderate regional cerebral blood flow abnormalities

Technetium-99m-1,1-ethyl cysteinate dimer (ECD) has been proposed as a "chemical microsphere" for SPECT measurement of regional cerebral blood flow (rCBF). However, its distribution has not yet been compared in humans to an established rCBF measure. Therefore, we compared the uptake and distribution of ECD with rCBF measured by 133Xe SPECT in subjects with mild to moderate flow abnormalities and in normal volunteers. Blood and urine chemistries and vital signs were unchanged from pre-ECD values up to seven days postinjection. Profile plots demonstrated pattern agreement between rCBF ratios (133Xe) and ECD count density ratios. A significant correlation of rCBF ratios to ECD count density ratios was observed (r = 0.77), with a slope of 0.64 and intercept of 0.36. To explore whether or not the relationship between rCBF and ECD was dependent on absolute flow, ECD region of interest data were expressed in units of ml/min/100 g by equating global CBF (133Xe) and ECD global count density. A closer correlation (r = 0.88) was found for these data than for the count ratio data. The slope was closer to one (m = 0.83) and the intercept was closer to zero (b = 8.2). Also, a significant correlation was observed between ECD-derived rCBF and 133Xe rCBF in the lesion area (r = 0.92) for patients with well-demarcated rCBF lesions. The slope (0.80) suggested a slight underestimation of lesion flow by ECD. Finally, ECD clearance from cortical gray matter ROIs derived from high-resolution scans from 1 to 4 hr postinjection was slow (2.4%/hr). In summary, ECD is a safe and effective marker of regional cerebral perfusion. The distribution of ECD is linearly related to rCBF measured by 133Xe SPECT, although our data suggest a mild underestimation of flow at the high end of the normal range.     

S-phase fractions of breast carcinomas. Relationships to morphology, estrogen and progesterone receptors, and early recurrence

Analysis of the S-phase fractions (SPF) measured by in vitro thymidine labeling, morphological appearances, and estrogen receptor (ER) assays of primary invasive breast carcinomas demonstrated several interrelationships. Lobular, mucinous, tubular, and adenocystic carcinomas consistently had low SPF and were usually positive for ER. The same was true for the carcinomas of no special histologic type [the not otherwise specified (NOS) group of E. R. Fisher including "infiltrating ductal" and undifferentiated carcinomas] with minimal anaplasia. Medullary, atypical medullary, and morphologically unclassifiable carcinomas with marked nuclear anaplasia nearly always had high SPF and were usually negative for ER. High SPF was associated with advanced stages of carcinoma initially or with early recurrence following mastectomy.     

Gram-negative anaerobic bacilli: Their role in infection and patterns of susceptibility to antimicrobial agents. II. Little-known Fusobacterium species and miscellaneous genera

Twenty infrequently reported species of gram-negative anaerobic bacilli other than Fusobacterium nucleatum, Fusobacterium necrophorum, and members of the genus Bacteroides were studied with regard to their role in infection and their susceptibility to antimicrobial agents. In addition, the literature regarding the recovery of these organisms from both the normal flora and infections of humans was reviewed. During a six-year period at the Wadsworth Clinical Anaerobic Bacteriology Research Laboratory (Veterans Administration Wadsworth Medical Center, Los Angeles, Calif.), 39 (6%) of 679 specimens obtained from anaerobic infections yielded "other gram-negative anaerobic bacilli" (OGNAB). Fusobacterium naviforme, Fusobacterium gonidiaformans, Fusobacterium varium, Fusobacterium mortiferum, and Fusobacterium russii were the most commonly isolated OGNAB. Most of the OGNAB tested were resistant to erythromycin, and most strains, except for F. varium, were susceptible to beta-lactam antibiotics and clindamycin. Chloramphenicol and metronidazole were active against all strains of OGNAB tested. Certain Fusobacterium species are undoubtedly previously unrecognized members of the normal flora of the oropharynx, upper respiratory tract, or urogenital tract and may be present in infections derived from these floras.     

Control of 0.2CaTiO3-0.8Li0.5Nd0.5TiO3 microwave dielectric ceramics by additions of Bi2Ti2O7

Ceramics of 0.2CaTiO₃-0.8Li_0.5Nd_0.5TiO₃) have been prepared by the mixed oxide route using additions of Bi₂O₃-2TiO₂ (up to 15 wt%). Powders were calcined 1100^∘C; cylindrical specimens were fired at temperatures in the range 1250–1325^∘C. Sintered products were typically 95% dense. The microstructures were dominated by angular grains 1–2 μm in size. With increasing levels of Bi₂O₃-2TiO₂ additions, needle and lath shaped second phases developed. For Bi₂Ti₂O₇ additions up to 5 wt%, the relative permittivity increased from 95 to 131, the product of dielectric Q value and measurement frequency increased from 2150 to 2450 GHz and the temperature coefficient of resonant frequency (τ _f ) increased from −28pp/^∘C to +22pp/^∘C. A product with temperature stable τ _f could be obtained at ∼2 wt% Bi₂Ti₂O₇ additions. For high levels of additives, there is minimal change in relative permittivity, the Qxf values degrade and τ _f becomes increasingly negative.     

A Generative Probabilistic Oriented Wavelet Model for Texture Segmentation

This Letter addresses image segmentation via a generative model approach. A Bayesian network (BNT) in the space of dyadic wavelet transform coefficients is introduced to model texture images. The model is similar to a Hidden Markov model (HMM), but with non-stationary transitive conditional probability distributions. It is composed of discrete hidden variables and observable Gaussian outputs for wavelet coefficients. In particular, the Gabor wavelet transform is considered. The introduced model is compared with the simplest joint Gaussian probabilistic model for Gabor wavelet coefficients for several textures from the Brodatz album [1]. The comparison is based on cross-validation and includes probabilistic model ensembles instead of single models. In addition, the robustness of the models to cope with additive Gaussian noise is investigated. We further study the feasibility of the introduced generative model for image segmentation in the novelty detection framework [2]. Two examples are considered: (i) sea surface pollution detection from intensity images and (ii) image segmentation of the still images with varying illumination across the scene.     

Energy-efficient induction motors performance characteristics andlife-cycle cost comparisons for centrifugal loads

When fixed-speed motors (fed directly at power frequency) are purchased for new installations or for replacements, the loaded shaft speed differences among motor options are either ignored or overestimated. The most common first-cut estimate is that the consumed shaft power will vary as the cube of the ratio of the motor rated nameplate speeds for centrifugal driven loads that have discharge control valves (on pressure or now control). In actuality, this is true only if the motors are loaded at approximately nameplate output. This paper discusses the true “control valve loss” factor taking into account actual speed differences among motor options. A simplified equation and figure are presented to permit quick evaluation of motor purchase alternatives for the lowest life-cycle cost based on efficiency and rated-load speed differences. NEMA standards on slip-speed variation should be made more stringent to increase the validity of speed-difference loss evaluations. Additionally, efficiency test results and loaded speed measurements for standard-efficiency and premium-efficiency 10 and 100 hp motors are presented, leading to a conclusion that standard-efficiency motors should be operated at no higher than rated voltage and that premium-efficiency motors should he operated at 5%-10% above rated voltage for best system efficiency