Episodic dermatolymphangioadenitis (DLA) in patients with lymphedema of the lower extremities before and after administration of benzathine penicillin: a preliminary study

Dermatolymphangioadenitis (DLA) is a common and serious complication of obstructive peripheral lymphedema. The clinical characteristics of acute DLA are local tenderness and erythema of the skin, sometimes red streaks along the distribution of the superficial lymphatics and enlarged inguinal lymph nodes. Systemic symptoms include malaise, fever and chills. In its subacute or latent form, only skin involvement is observed. Each episode of DLA is commonly followed by worsening of leg swelling. Numerous clinical studies suggest that administration of antibiotic drugs interrupt the acute episodes and prevent their recurrence. We investigated the clinical course of lymphedema with respect to the prevalence of DLA in patients receiving injections of long-acting penicillin (benzathine penicillin). Forty-five randomly selected patients with obstructive lymphedema of the lower limbs were included in an open clinical trial. The inclusion criteria was stage II-IV lymphedema of postsurgical, posttraumatic, and postdermatitis type with at least 3 previous episodes of DLA. Benzathine penicillin (PCN) was given after the last presenting episode of DLA in a dose of 1,200,000 u, intramuscularly at 3-week intervals, for at least one year. Each patient was reevaluated at 3-month intervals. They were instructed in early diagnosis of DLA and reported promptly to the responsible senior surgeon with prodrome symptoms of recurrent DLA. The duration of lymphedema before initiation of therapy was 7 months to 40 years and the frequency of DLA was 1-6 episodes per year. PCN administration lasted for at least one year but was extended in all patients because of the tendency for recurrence of DLA after cessation of PCN injections. In 26 of these patients, PCN administration extended to over 5 years and in 2 over 10 years. Recurrent episodes of DLA occurred in the PCN-treated group during one year follow-up in only 4 of the 45 patients (9%). The frequency episodes in 3 patients with recurrent DLA was 1-2/year; in one patient, no positive effect of PCN therapy was observed. There were no apparent side effects of long-term PCN therapy. These data, although evaluated without a placebo group, suggest that long-term PCN administration decreases the frequency of DLA attacks and furthermore provide justification for carrying out a double-blind randomly placebo-controlled clinical trial of the efficacy of prophylactic antibiotic drug treatment in forestalling DLA episodes.     

绝缘油对复合绝缘子伞裙性能的影响及其变形原因分析

复合绝缘子在变电站涉油设备装配过程中可能因人为操作、密封性能不佳等原因,其伞裙会因接触绝缘油而出现变形.为进一步研究绝缘油对复合绝缘子伞裙的影响并分析其变形原因,采用绝缘油处理伞裙硅橡胶材料,分析了硅橡胶的体积变化、化学结构、憎水性、力学性能、电气性能.结果表明:绝缘油导致硅橡胶的体积变大,断裂伸长率、拉伸强度、撕裂强度、硬度减小,这与伞裙硅橡胶材料的物理溶胀有关.基于此,利用滴油装置及绝缘子模拟再现伞裙发生变形的过程,最终提出一种利用热处理恢复伞裙形变的方法.     

定容条件下火药实际燃烧规律的数值模拟

为研究火药的实际燃烧规律,建立了定容条件下火药燃烧的修正数学模型,分析了火药实际弧厚的分布及变化、点火不同步和燃速系数变化等因素对火药实际燃烧规律的影响。在此基础上,用考虑综合因素的修正数学模型对定容条件下火药的实际燃烧过程进行了模拟,计算值与实验结果具有较好的一致性,说明修正模型所建立的假设及处理方案是合理的。     

主成分分析法在学生成绩分析中的应用

本文从大学四年成绩的真实数据入手,利用主成分分析法,建立了数学模型,然后给出各主成分的得分函数,并结合成绩进行分析,最后得出影响成绩的主要课程,并验证了学校实行的学分绩是合理的。该研究结果为今后的教学研究和管理提供了科学的依据。     

一种基于纹理特征的图像垃圾邮件的识别方法

越来越多的垃圾邮件将文字制作成图片以逃避基于文字识别的反垃圾邮件过滤技术,目前采用的识别技术检测率低,而且容易被图像中故意加入的背景噪点干扰。介绍了一种用Gabor滤波器提取图片纹理特征并结合支持向量机（SVM）进行分类的识别方法,在实验中取得了较高的抗干扰率和检测率。     

Bithalamic hyperintensity on T2-weighted MR: vascular causes and evaluation with MR angiography

PURPOSE: To determine whether MR angiography can be used to differentiate between the two vascular causes of bithalamic hyperintensity on T2-weighted MR images: "top of the basilar" artery occlusion and deep cerebral vein thrombosis. METHODS: A retrospective review identified six patients with bithalamic T2 hyperintensity of vascular causes. MR angiography was performed in four patients, MR angiography and conventional angiography in one patient, and conventional angiography in one patient. Data pertaining to clinical presentation and hospital course were collected. MR angiographic techniques were multislab overlapping three-dimensional time-of-flight, 2-D time-of-flight, and 2-D phase-contrast. RESULTS: Three cases of top of the basilar artery occlusion and three cases of deep cerebral vein thrombosis were recognized. In all cases, T2 hyperintensity in a vascular distribution suggested cerebral occlusive disease. Infarction involving the thalami and basal ganglia was present in two cases of deep cerebral vein thrombosis. Infarction of the thalami, mesodiencephalic region, and cerebellar hemispheres was present in two cases of basilar artery occlusion. Bithalamic infarction alone was seen in one case of deep cerebral vein thrombosis and one case of basilar artery occlusion. In the five cases in which MR angiography was used, this technique accurately distinguished the vessels involved (arterial or venous). CONCLUSION: MR angiography is a useful adjunct to MR imaging in the evaluation of bithalamic T2 hyperintensity. It does help distinguish between the two vascular causes: top of basilar artery occlusion and deep cerebral vein thrombosis.     

S-phase fractions of breast carcinomas. Relationships to morphology, estrogen and progesterone receptors, and early recurrence

Analysis of the S-phase fractions (SPF) measured by in vitro thymidine labeling, morphological appearances, and estrogen receptor (ER) assays of primary invasive breast carcinomas demonstrated several interrelationships. Lobular, mucinous, tubular, and adenocystic carcinomas consistently had low SPF and were usually positive for ER. The same was true for the carcinomas of no special histologic type [the not otherwise specified (NOS) group of E. R. Fisher including "infiltrating ductal" and undifferentiated carcinomas] with minimal anaplasia. Medullary, atypical medullary, and morphologically unclassifiable carcinomas with marked nuclear anaplasia nearly always had high SPF and were usually negative for ER. High SPF was associated with advanced stages of carcinoma initially or with early recurrence following mastectomy.     

Gram-negative anaerobic bacilli: Their role in infection and patterns of susceptibility to antimicrobial agents. II. Little-known Fusobacterium species and miscellaneous genera

Twenty infrequently reported species of gram-negative anaerobic bacilli other than Fusobacterium nucleatum, Fusobacterium necrophorum, and members of the genus Bacteroides were studied with regard to their role in infection and their susceptibility to antimicrobial agents. In addition, the literature regarding the recovery of these organisms from both the normal flora and infections of humans was reviewed. During a six-year period at the Wadsworth Clinical Anaerobic Bacteriology Research Laboratory (Veterans Administration Wadsworth Medical Center, Los Angeles, Calif.), 39 (6%) of 679 specimens obtained from anaerobic infections yielded "other gram-negative anaerobic bacilli" (OGNAB). Fusobacterium naviforme, Fusobacterium gonidiaformans, Fusobacterium varium, Fusobacterium mortiferum, and Fusobacterium russii were the most commonly isolated OGNAB. Most of the OGNAB tested were resistant to erythromycin, and most strains, except for F. varium, were susceptible to beta-lactam antibiotics and clindamycin. Chloramphenicol and metronidazole were active against all strains of OGNAB tested. Certain Fusobacterium species are undoubtedly previously unrecognized members of the normal flora of the oropharynx, upper respiratory tract, or urogenital tract and may be present in infections derived from these floras.     

基于工作流的电网检修计划管理系统研究

为实现电网检修计划管理业务流程的网络化、自动化,利用微软的工作流新技术W indows W orkflowFoundation(WWF),提出了基于MS.NET平台的电网检修计划管理系统解决方案。利用Petri网对一个典型的电网检修计划业务流程建模并分析所建模型的正确性,给出了基于WWF模型驱动和面向组件实现所建电网检修计划工作流模型的可视化设计方法,能够较好地满足实际应用的需要,具有实现成本低、开发难度小,系统灵活性、可扩展性好等优点。