The ultrastructure of an olfactory sensillum on the maxillary palps of locusta migratoria (L.)

The olfactory sensilla on the maxillary palp tip of Locusta migratoria (L.) resemble the surrounding contact chemoreceptors in general morphology. The perforated peg has a thicker wall than is commonly found in olfactory sensilla. The form and position of the sensilla are considered in relation of the olfactory function. The fine structure of the dendrites is discussed in relation to that described in other olfactory sensilla.     

Pantothenic acid, coenzyme A, and human chronic ulcerative and granulomatous colitis

To investigate further an apparent relationship between chronic ulcerative and granulomatous colitis and pantothenic acid deficiency, colonic tissues obtained at the time of colectomy in 29 patients with these disorders were assayed for pantothenic acid and for coenzyme A (CoA) activity. For comparison, normal colonic tissues free of pathological lesions were obtained from 31 patients having colectomy for carcinoma or diverticulitis. Plasma, red blood cells, and colonic mucosa were assayed microbiologically for free and total pantothenic acid. The activity of CoA in colonic mucosa was determined by assaying the acetylation of sulfanilamide. Concentrations of free, bound, and total pantothenic acid in blood and in colonic mucosa did not differ between the two groups of patients. Bound pantothenic acid increased linearly with total pantothenic acid. Colonic mucosa concentrated free pantothenic acid to about 50 times the level of blood, and pantothenic acid in red cells was similar to the concentration in plasma. Compared to normal gut mucosa, CoA activity was markedly low in mucosa from patients with chronic ulcerative or granulomatous disease despite the presence of normal amounts of free and bound pantothenic acid. A block in the conversion of bound pantothenic acid to CoA in diseased mucosa is suggested.     

A simple theory to predict the threshold voltage of short-channel IGFET's

A simple expression for the threshold voltage of an IGFET is derived from a charge conservation principle which geometrically takes into account two-dimensional edge effects. The expression is derived for zero drain voltage and is valid for short and long-channel lengths. The dependence of the threshold voltage on the source and drain diffusion depth, r_j, and channel length, L, is explicitly given. In the limit, L/r_j → ∞, the threshold voltage equation reduces to the familiar expression for the long-channel case.The theory is compared with the measured threshold voltages on IGFET's fabricated with 1·4, 3·8 and 7·4 μm channel lengths. The dependence of the threshold voltage under backgate bias voltages ranging from zero to breakdown agrees closely with the theory.     

A direct method for cluster analysis

An algorithm based on a least-mean-square (LMS) criterion is presented. This algorithm partitions a multi-dimensional data set directly into a desired number of clusters. The result is compared favorably to existing methods in both performance and computational efficiency. An efficient method for determining a reasonable set of distributed initial cluster centers based on principal component analysis is also presented. This clustering algorithm is shown to converge to a unique minimum based on the LMS criterion and is demonstrated by digital computer simulation and applied to the analysis of vectorcardiograms.