Abstractness of implicit grammar knowledge: Comments on Perruchet and Pacteau's analysis of synthetic grammar learning.

On the basis of 3 experiments, P. Perruchet and C. Pacteau (see record 1991-00329-001) argued that implicitly acquired knowledge of a synthetic grammar consists of little more than knowledge of pairwise associations between pairs of letters in the grammar. By comparing their results with a study by R. C. Mathews et al (see record 1990-03549-001), it is argued that (a) implicitly acquired knowledge is much richer and more abstract than suggested by Perruchet and Pacteau, (b) their recognition measures are less sensitive than the recall measures of Mathews et al for detecting conscious awareness of implicit knowledge, and (c) fragmentary knowledge of a grammar constitutes abstract rules that enable performance of complex tasks when integrated into a system for combining knowledge across rules. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Nonclinical model for assessing gastric effects of bisphosphonates

Mechanisms by which ketones potentiate manganese-bilirubin (Mn-BR)-induced cholestasis are unknown. The purpose of the present study was to investigate the effect of methyl isobutyl ketone (MiBK), a widely used ketonic solvent, at the level of the bile canalicular membrane (BCM) and to verify if altered membrane lipid dynamics could be involved in MiBK-potentiated Mn-BR cholestasis. Male Sprague-Dawley rats were exposed 4 hr/day for 3 days to MiBK vapors (200 or 600 ppm). Eighteen hours after the last exposure, manganese (Mn, 4.5 mg/kg) was given i.v. followed 15 min later by bilirubin (BR, 25 mg/kg). Rats were killed 30 min after BR; liver cell plasma membranes (bile canalicular and sinusoidal), microsomes, mitochondria, and cytosol were isolated by differential centrifugation. Lipids were extracted and cholesterol was measured in each fraction. After Mn-BR and MiBK exposure (600 ppm), results indicated a marked increase in BCM cholesterol content compared to rats exposed to air only. This increase was greater than that due to Mn-BR or MiBK given alone. Also, results indicated that cholesterol increased in a dose-related fashion in BCM after MiBK exposure, whereas PM cholesterol remained unaltered. To identify the source of the increased BCM cholesterol and to permit distinction between de novo cholesterol synthesis and subcellular shifts, the hepatic lipid pool was labeled in vivo with [3H]-cholesterol and [2-14C]-mevalonic acid, a cholesterol synthesis precursor. Results showed that after 600 ppm MiBK exposure, 14C-labeled cholesterol was greater than 3H-labeled cholesterol, indicating that the contribution of de novo cholesterol synthesis to the total cholesterol content of the various isolated hepatocellular fractions was more important than the contribution of intracellular pools. Therefore, increased BCM cholesterol content and enhanced accumulation of newly synthesized cholesterol appear to be involved in MiBK potentiation of Mn-BR-induced cholestasis.     

Nonlinearities in digital manifold phased arrays

In digital beamforming (DBF), the phase shifter is functionally replaced with a receiver and digital phase rotation. A Taylor series expansion of mixer nonlinearities is used to generate receiver intermodulation spectrums respective of the element position and the iso-Doppler wavefront directions of signal arrival across the array. The dominant intermodulation distortion at each element experiences linear phase errors across the array proportional to the harmonic number and the desired steering direction phase gradient. The array distortion signals are reduced relative to the desired signal by the array factor sidelobe isolation when desired collimation directions exceed a few beamwidths of scan off the array normal vector. The result of the nonlinear down conversion analysis is extended to inphase and quadrature imbalances and batch manufacturing tolerances for element receivers.     

An interactional model of independence.

Proposes an interactional model of independence that focuses on personal and environmental variables. Personal variables in rehabilitation include physical abilities, knowledge and skills, and values and goals. Environmental variables include the physical environment, social networks and service programs, and the system of laws, policies, and public attitudes that guide institutional responses to people with disabilities. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Limestone Neutralisation of Arsenic-Rich Effluent from a Gold Mine

Traditionally acid mine water is neutralised with lime. Limestone is a cheaper alternative for such applications. A case study showed that limestone can be used effectively to replace lime for the neutralization of arsenic rich acid water. The cost of limestone treatment is 45.8% less than that of lime. The acidity can be removed from 33.5 to 0.06 g/L (as CaCO₃). The study also showed no significant differences in the TCLP characteristics of the resultant sludge when water is treated with lime or with limestone. Sludge from the limestone treatment process can be disposed of on a non-hazardous landfill site. An erratum to this article can be found at