Nuclear data sheets for A = 185

The available nuclear structure information for all nuclei with mass number A=185 is presented. Various decay and reaction data are evaluated and compared. Adopted data, levels, spin, parity, and configuration assignments are given.     

Structural and immunologic studies of Proteus mirabilis 033 O-specific polysaccharide

A variety of adrenal imaging agents have been used in nuclear medicine, but no agent has been developed for magnetic resonance (MR) imaging. The authors have previously observed accumulation of aminated macromolecules in adrenal glands. They now report the synthesis of a model polymeric aminated contrast agent for enhanced MR imaging of the adrenal glands. The model agent consisted of a poly-L-lysine conjugate (molecular weight, 245 kd) that had 70% free epsilon amino groups and 30% diethylenetriaminepentaacetic acid (DTPA)-derivatized amino groups to bind indium-111 or gadolinium. One hour after intravenous administration of this compound, adrenal uptake was 10.1% +/- 0.7 of injected dose per gram of tissue. When all free epsilon amino groups of the polylysine were completely substituted with DTPA, adrenal uptake was 3.4 times lower, indicating the importance of free amino groups for adrenal uptake. MR imaging in rats showed that a dose of 0.08 mmol of gadolinium per kilogram of the agent was sufficient to enhance the signal intensity of adrenal glands. There hours after intravenous administration of the agent, signal intensity of the adrenal glands was 186% of precontrast values (liver, 165%; kidney, 91%). Fluorescence microscopy showed that the agent accumulated primarily in the cortical zona glomerulosa and in the adrenal medulla. These initial studies demonstrate the feasibility of designing contrast agents for MR imaging of the adrenal glands.     

Nedocromil sodium inhibits T-cell function in vitro and in vivo

Nedocromil sodium, a topical antiinflammatory agent recommended as a prophylactic regimen for asthma, is known to inhibit both allergic and nonallergic inflammatory processes in which an essential role for T cells has been implicated. Therefore the direct effects of this drug on several aspects of T-cell activity were analyzed in the present study. By using murine lymphocytes we found that NS at concentrations of 10(-8) to 10(-6) mol/L inhibited the mitogen- or antigen-induced proliferative responses of these cells. It is interesting to note that higher concentrations were ineffective. Preincubation of immune lymph node cells from contact sensitized mice with the drug abrogated their ability to transfer contact sensitivity to naive recipients, an effect that was found to be specific for the treated cells. Nedocromil sodium also interfered with the mitogen-induced interleukin-2 and tumor necrosis factor production by T cells and with their ability to adhere to the bound protein components of the extracellular matrix laminin and fibronectin. All these effects may be attributed to the inhibition of the increase of cytosolic calcium, which accompanies the early phase of T-cell activation and which is an essential step in inducing the aforementioned phenomena.     

网络教学平台选择与应用策略

通过比较国内外几种知名的网络教学平台,根据现阶段高校信息化与数字化校园建设需求,提出高校网络教学平台的选择与应用策略。     

可食胶原肠衣及其在肉类加工中的应用

介绍了胶原肠衣的生产工艺、过程和相关信息,并且对于实际使用过程常见问题进行讨论。     

烟用香精调配稳定性的X质量控制图监控

为了监控二次调配烟用香精的稳定性,建立了采用检测相对密度、GC法测定各批次调配香精含水率、乙醇和丙二醇及某些特有成分含量的变化,并根据其X-质量控制图上、下控制限监控香精调配稳定性的方法。     

CHANGES OF CELL WALL COMPONENTS AND PAL ACTIVITY IN FRESH-CUT BAMBOO SHOOTS DURING COLD STORAGE

Changes of cell wall components in relation to softening and lignifying of fresh-cut bamboo shoots (Phyllostachys heterocycla var. pubescens) was investigated. Increased activity of phenylalanine ammonia-lyase (PAL) was related to a rise of lignin content in the basal section but not in the middle and apical sections. PAL activity was also associated with an increase in phenolic content in the middle section, but not in the basal and apical sections. The softening process occurred mainly in the apical section, while lignification took place primarily in the basal section. In the middle section, both softening and lignification also occurred but to a lesser extent.     

Photocleavage of Water in Organized Molecular Systems

Photocleavage of water by solar light in molecular systems is discussed. The advantages of organized molecular photosystems are demonstrated for the main steps of the photocleavage process: charge photoseparation, stabilization of the separated charges, and catalytic production of hydrogen and oxygen under the action of one-electron reductants and oxidants, respectively.