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991.
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993.
Dimensional synthesis is a type of inverse problem in linkage kinematics where the objective is to calculate the linkage dimensions required to achieve prescribed linkage output motion. Motion generation is a particular category of dimensional synthesis where the objective is to calculate the linkage dimensions required to achieve a group of prescribed link positions. In motion generation for a four-bar linkage, positions are prescribed for the coupler link. While early motion generation methods were primarily qualitative, ongoing advancements in computing hardware and software continue to make quantitative motion generation more practical. By providing overviews of works representative of developments in quantitative four-bar motion generation since 1970, this work is essentially an overview that spans over 40 years of developments in quantitative four-bar motion generation. 相似文献
994.
Qingqing Xiong Gha Young Lee Jianxun Ding Wenliang Li Jinjun Shi 《Nano Research》2018,11(10):5281-5309
As an attractive alternative to plasmid DNA, messenger RNA (mRNA) has recently emerged as a promising class of nucleic acid therapeutics for biomedical applications. Advances in addressing the inherent shortcomings of mRNA and in the development of nanoparticle-based delivery systems have prompted the development and clinical translation of mRNA-based medicines. In this review, we discuss the chemical modification strategies of mRNA to improve its stability, minimize immune responses, and enhance translational efficacy. We also highlight recent progress in nanoparticle-based mRNA delivery. Considerable attention is given to the increasingly widespread applications of mRNA nanomedicine in the biomedical fields of vaccination, protein-replacement therapy, gene editing, and cellular reprogramming and engineering. 相似文献
995.
We explore the impact of edge states in three types of transition metal dichalcogenides (TMDs), namely metallic Td-phase WTe2 and semiconducting 2H-phase MoTe2 and MoS2, by patterning thin flakes into ribbons with varying channel widths. No obvious charge depletion at the edges is observed for any of these three materials, in contrast to observations made for graphene nanoribbon devices. The semiconducting ribbons are characterized in a three-terminal field-effect transistor (FET) geometry. In addition, two ribbon array designs have been carefully investigated and found to exhibit current levels higher than those observed for conventional one-channel devices. Our results suggest that device structures incorporating a high number of edges can improve the performance of TMD FETs. This improvement is attributed to a higher local electric field, resulting from the edges, increasing the effective number of charge carriers, and the absence of any detrimental edge-related scattering. 相似文献
996.
Kim Kihyeun Son Myungwoo Pak Yusin Chee Sang-Soo Auxilia Francis Malar Lee Byung-Kee Lee Sungeun Kang Sun Kil Lee Chaedeok Lee Jeong Soo Kim Ki Kang Jang Yun Hee Lee Byoung Hun Jung Gun-Young Ham Moon-Ho 《Nano Research》2018,11(7):3957-3957
Nano Research - The order of the authors in the original version of this article was unfortunately incorrect on the first page and the first page of the ESM. Instead of Myungwoo Son1, Yusin Pak1,... 相似文献
997.
Kien Tiek Wong Boris Brigljević Jeong Hyeon Lee So Yeon Yoon Seok Byum Jang Choe Earn Choong Inwook Nah Hyeongjun Kim Hyun-Seog Roh Sang Kyu Kwak Hankwon Lim Min Jang 《Small (Weinheim an der Bergstrasse, Germany)》2023,19(1):2204336
This study focuses on the applicability of single-atom Mo-doped graphitic carbon nitride (GCN) nanosheets which are specifically engineered with high surface area (exfoliated GCN), NH2 rich edges, and maximum utilization of isolated atomic Mo for propylene carbonate (PC) production through CO2 cycloaddition of propylene oxide (PO). Various operational parameters are optimized, for example, temperature (130 °C), pressure (20 bar), catalyst (Mo2GCN), and catalyst mass (0.1 g). Under optimal conditions, 2% Mo-doped GCN (Mo2GCN) has the highest catalytic performance, especially the turnover frequency (TOF) obtained, 36.4 h−1 is higher than most reported studies. DFT simulations prove the catalytic performance of Mo2GCN significantly decreases the activation energy barrier for PO ring-opening from 50–60 to 4.903 kcal mol−1. Coexistence of Lewis acid/base group improves the CO2 cycloaddition performance by the formation of coordination bond between electron-deficient Mo atom with O atom of PO, while NH2 surface group disrupts the stability of CO2 bond by donating electrons into its low-level empty orbital. Steady-state process simulation of the industrial-scale consumes 4.4 ton h−1 of CO2 with PC production of 10.2 ton h−1. Techno-economic assessment profit from Mo2GCN is estimated to be 60.39 million USD year−1 at a catalyst loss rate of 0.01 wt% h−1. 相似文献
998.
Yeongin Kim Chenxin Zhu Wen-Ya Lee Anna Smith Haowen Ma Xiang Li Donghee Son Naoji Matsuhisa Jaemin Kim Won-Gyu Bae Sung Ho Cho Myung-Gil Kim Tadanori Kurosawa Toru Katsumata John W. F. To Jin Young Oh Seonghyun Paik Soo Jin Kim Lihua Jin Feng Yan Jeffrey B.-H. Tok Zhenan Bao 《Advanced materials (Deerfield Beach, Fla.)》2023,35(1):2203541
Hemispherical image sensors simplify lens designs, reduce optical aberrations, and improve image resolution for compact wide-field-of-view cameras. To achieve hemispherical image sensors, organic materials are promising candidates due to the following advantages: tunability of optoelectronic/spectral response and low-temperature low-cost processes. Here, a photolithographic process is developed to prepare a hemispherical image sensor array using organic thin film photomemory transistors with a density of 308 pixels per square centimeter. This design includes only one photomemory transistor as a single active pixel, in contrast to the conventional pixel architecture, consisting of select/readout/reset transistors and a photodiode. The organic photomemory transistor, comprising light-sensitive organic semiconductor and charge-trapping dielectric, is able to achieve a linear photoresponse (light intensity range, from 1 to 50 W m−2), along with a responsivity as high as 1.6 A W−1 (wavelength = 465 nm) for a dark current of 0.24 A m−2 (drain voltage = −1.5 V). These observed values represent the best responsivity for similar dark currents among all the reported hemispherical image sensor arrays to date. A transfer method was further developed that does not damage organic materials for hemispherical organic photomemory transistor arrays. These developed techniques are scalable and are amenable for other high-resolution 3D organic semiconductor devices. 相似文献
999.
1000.
BK Park ES Cho JD Lee C Oh MS Lee SZ Kim SH Kim KW Cho 《Canadian Metallurgical Quarterly》1998,43(8):611-618
The effect of a naturally occurring plant phenolic constituent (the acylphloroglucinol derivative, jensenone, derived from Eucalyptus jensenii) on the food intake of two folivorous marsupials, the common ringtail (Pseudocheirus peregrinus) and the common brushtail possum (Trichosurus vulpecula) was studied. When fed diets containing varying concentrations of jensenone, both species regulated their intake of jensenone so as not to exceed a ceiling intake. This ceiling was about twice as high for common ringtails as for common brushtails from northern Australia. Southern populations of common ringtails showed greatly reduced capacities to tolerate jensenone. When common brushtails were injected (0.5 mg.kg-0.75 body mass) with ondansetron (a selective antagonist of serotonin 5HT3 receptors), they ate significantly more jensenone than animals injected with physiological saline. The same pattern was observed when common ringtails were fed diets containing both jensenone and ondansetron (0.0035 mg.g-1 wet mass of diet). Ondansetron injection had no effect on food intake when the food did not contain jensenone while the addition of higher doses of ondansetron to diets of common ringtails very slightly reduced food intakes of a non-jensenone diet. When common brushtails were given 50 mg of jensenone by gastric lavage, their average subsequent intake of dietary jensenone matched the difference between the daily threshold and the dose given, although the response of individuals was highly variable. Lavage with water alone had no effect on subsequent jensenone intake compared with the pre-dose period. We interpret these results as evidence that the antifeedant effects of jensenone and related compounds are partly mediated by serotonin action on 5HT3 receptors most likely via "nausea" to condition a food aversion. 相似文献