Differentiation of mesencephalic progenitor cells into dopaminergic neurons by cytokines

1. This study examines the effects of exercise training and chronic ethanol consumption on cholinesterase activity and its relationship to lipid peroxidation in blood and brain regions of rat. 2. Exercise training (6.5 weeks) decreased acetylcholinesterase (AChE) activity significantly (64% of control) in hypothalamus and increased AChE activity in cerebral cortex (149% of control), whereas, malondialdehyde (MDA) levels increased in hypothalamus (129% of control) and decreased in cortex, striatum, and cerebellum (50%, 69% and 75% of control), respectively. 3. Chronic ethanol ingestion (2.0 gm/kg, p.o. for 6.5 weeks) significantly increased butyrylcholinesterase (BuChE) activity in plasma (136% of control) and decreased AChE activity in hypothalamus (63% of control), whereas, MDA levels increased in hypothalamus, cortex, and plasma (140%, 130% and 220% of control), respectively. 4. The combination significantly increased BuChE activity (173% of control) in plasma and decreased AChE activity (71% of control) in hypothalamus and (57% of control) in cerebellum, whereas, MDA levels increased in hypothalamus, cerebellum, medulla and plasma (134%, 128%, 140% and 309% of control), respectively. 5. Exercise training, chronic ethanol ingestion, and combination selectively inhibited hypothalamic AChE and the inhibition was correlated with increased lipid peroxidation (r = 0.11, 0.41 and 0.45) which may perturb hypothalamic function. The combination enhanced the peripheral stress response by increasing plasma BuChE activity and lipid peroxidation.     

ZD203型温控不锈钢煮茧机的设计与实效

文章介绍了ZD203型不锈钢温控煮茧机的设计依据及工艺性能,机械结构及自控系统等装置特点,通过多家缫丝厂长期生产结果表明,该机工艺性能优良,煮熟茧质量好,原料适应性强,自立缫可兼用,机械结构紧凑合理,能耗显著减少,总蒸气压力控制及主要区段温度控制系统具有实用性强,可靠性高,维修方便等特点,是目前国内先进设备。