通过在线客户体验来推动销售

21世纪的消费者在消费体验方面更有自己的主张,直复营销也有了发展。尤其是那些已推出在线业务的企业,已有能力与个人进行互动。     

Integrating scientific modeling and supporting dynamic hazard management with a GeoAgent-based representation of human–environment interactions: A drought example in Central Pennsylvania, USA

Recent natural disasters indicate that modern technologies for environmental monitoring, modeling, and forecasting are not well integrated with cross-level social responses in many hazard-management systems. This research addresses this problem through a Java-based multi-agent prototype system, GeoAgent-based Knowledge System (GeoAgentKS). This system allows: (1) computer representation of institutional regulations and behavioral rules used by multiple social institutions and individuals in cross-level human–environment interactions, (2) integration of this representation with scientific modeling of dynamic hazard development, and (3) application of automated reasoning that suggests to users the appropriate actions for supporting cooperative social responses. This paper demonstrates the software architecture of GeoAgentKS and presents such an integrated approach by modeling the drought management processes in Central Pennsylvania, USA. The results show that it is possible to use GeoAgentKS to represent multilevel human–environment interactions and to use those interactions as input to decision making in hazard management.     

A taxonomy for and analysis of multi-person-display ecosystems

Interactive displays are increasingly being distributed in a broad spectrum of everyday life environments: they have very diverse form factors and portability characteristics, support a variety of interaction techniques, and can be used by a variable number of people. The coupling of multiple displays creates an interactive “ecosystem of displays”. Such an ecosystem is suitable for particular social contexts, which in turn generates novel settings for communication and performance and challenges in ownership. This paper aims at providing a design space that can inform the designers of such ecosystems. To this end, we provide a taxonomy that builds on the size of the ecosystem and on the degree of individual engagement as dimensions. We recognize areas where physical constraints imply certain kinds of social engagement, versus other areas where further work on interaction techniques for coupling displays can open new design spaces.     

Improving the availability and cost-effectiveness of guidelines for guideline-users: towards a structured approach

The achievement of design and development solutions can be enhanced through consulting appropriate guidelines Although a wide range exist, frequently their full benefits are not realized by guideline-users because of the costs associated with their use. Guideline-users are people who use guidelines to support purposeful activity. Major cost drivers for guideline-users are the processes of 'selecting' appropriate guidelines and their subsequent 'translation' to an applied setting both of which can be prohibitively expensive. A strategy for producing guidelines is proposed, to minimize these costs, which is illustrated by the use of a case study concerned with the development of guidelines to assist in the production of management and administrative tools which will support project managers concerned with Human Factors Acceptance Testing. A process to support the assessment of guidelines is also proposed.     

The Challenges of Cross-Modal Translation: English-to-Sign-Language Translation in the Zardoz System

The sign languages used by deaf communities around the world represent a linguistic challenge that natural-language researchers in AI have only recently begun to take up. This challenge is particularly relevant to research in Machine Translation (MT), as natural sign languages have evolved in deaf communities into efficient modes of gestural communication, which differ from English not only in modality but in grammatical structure, exploiting a higher dimensionality of spatial expression. In this paper we describe Zardoz, an on-going AI research system that tackles the cross-modal MT problem, translating English text into fluid sign language. The paper presents an architectural overview of Zardoz, describing its central blackboard organization, the nature of its interlingual representation, and the major components which interact through this blackboard both to analyze the verbal input and generate the corresponding gestural output in one of a number of sign variants.     

Physical Maltreatment Victim to Antisocial Child: Evidence of an Environmentally Mediated Process.

The well-documented finding that child physical maltreatment predicts later antisocial behavior has at least 2 explanations: (a) Physical maltreatment causes antisocial behavior, and (b) genetic factors transmitted from parents to children influence the likelihood that parents will be abusive and that children will engage in antisocial behavior. The authors tested these hypotheses in the representative Environmental-Risk cohort of 1,116 twin pairs and their families, who were assessed when the twins were 5 and 7 years old. Mothers reported on children's experience of physical maltreatment, and mothers and teachers reported on children's antisocial behavior. The findings support the hypothesis that physical maltreatment plays a causal role in the development of children's antisocial behavior and that preventing maltreatment can prevent its violent sequelae. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

OLED初具市场规模

We have all heard the hype about OLED displays and that they are going to offer great picture quality as well as energy efficiency in a very thin profile package. The issue at hand is whether they will be priced competitively in the market and overcome some of their shortcomings in the short term.     

Tumor Infiltration with CD20+CD73+ B Cells Correlates with Better Outcome in Colorectal Cancer

Immunotherapy has become increasingly important in the treatment of colorectal cancer (CRC). Currently, CD73, also known as ecto-5′-nucleotidase (NT5E), has gained considerable interest as a potential therapeutic target. CD73 is one of the key enzymes catalyzing the conversion of extracellular ATP into adenosine, which in turn exerts potent immune suppressive effects. However, the role of CD73 expression on various cell types within the CRC tumor microenvironment remains unresolved. The expression of CD73 on various cell types has been described recently, but the role of CD73 on B-cells in CRC remains unclear. Therefore, we analyzed CD73 on B-cells, especially on tumor-infiltrating B-cells, in paired tumor and adjacent normal tissue samples from 62 eligible CRC patients. The highest expression of CD73 on tumor-infiltrating B-cells was identified on class-switched memory B-cells, followed by naive B-cells, whereas no CD73 expression was observed on plasmablasts. Clinicopathological correlation analysis revealed that higher CD73⁺ B-cells infiltration in the CRC tumors was associated with better overall survival. Moreover, metastasized patients showed a significantly decreased number of tumor-infiltrating CD73⁺ B-cells. Finally, neoadjuvant therapy correlated with reduced CD73⁺ B-cell numbers and CD73 expression on B-cells in the CRC tumors. As promising new immune therapies are being developed, the role of CD73⁺ B-cells and their subsets in the development of colorectal cancer should be further explored to find new therapeutic options.     

Memory capacity, selective control, and value-directed remembering in children with and without attention-deficit/hyperactivity disorder (ADHD).

Objective: The ability to select what is important to remember, to attend to this information, and to recall high-value items leads to the efficient use of memory. The present study examined how children with and without attention-deficit/hyperactivity disorder (ADHD) performed on an incentive-based selectivity task in which to-be-remembered items were worth different point values. Method: Participants were 6–9 year old children with ADHD (n = 57) and without ADHD (n = 59). Using a selectivity task, participants studied words paired with point values and were asked to maximize their score, which was the overall value of the items they recalled. This task allows for measures of memory capacity and the ability to selectively remember high-value items. Results: Although there were no significant between-groups differences in the number of words recalled (memory capacity), children with ADHD were less selective than children in the control group in terms of the value of the items they recalled (control of memory). All children recalled more high-value items than low-value items and showed some learning with task experience, but children with ADHD Combined type did not efficiently maximize memory performance (as measured by a selectivity index) relative to children with ADHD Inattentive type and healthy controls, who did not differ significantly from one another. Conclusions: Children with ADHD Combined type exhibit impairments in the strategic and efficient encoding and recall of high-value items. The findings have implications for theories of memory dysfunction in childhood ADHD and the key role of metacognition, cognitive control, and value-directed remembering when considering the strategic use of memory. (PsycINFO Database Record (c) 2010 APA, all rights reserved)