杂交空间结构的预应力全过程分析方法

杂交空间结构系由不同类型的单一结构形式组合而成的空间结构体系,预应力全过程分析是其关键和难点。结合几类典型的杂交空间结构工程实践,详细讨论了不同结构形式中采用的预应力模拟和全过程分析方法,提出了初始形变迭代分析法、初始形变顺序分析法、升温降温法、模拟千斤顶法、影响矩阵迭代法等预应力分析方法,完善了杂交空间结构的预应力分析理论,并通过对实际工程的分析验证了这些方法的准确性。     

湖南电力系统冰灾监测结果及其分析

湖南电网2008年遭受了罕见的冰灾,输电线路损失严重.研制了一套输电线路灾情监测系统,在湖南电网推广应用68套.该系统在2008年冰灾中,准确地监视到线路覆冰情况,为线路防冰提供决策依据.通过系统的监测数据,发现本次冰灾具有强度大、覆冰重心区转移、覆冰与海拔关系不明显、受微地形微气象影响显著等特点,为今后防冰工作提供参考.     

新型邻苯二甲酰胺类杀虫剂的研究进展

介绍了新型邻苯二甲酰胺类鱼尼丁受体杀虫剂的研究进展,包括国内外各大农药公司近年来公开的具有较好活性的化合物以及即将商品化产品氟虫酰胺(flubendiamide)的创制经纬和合成方法。     

可编程直接序列扩频通信系统的数字化实现

本文讨论了利用ASIC芯片和CPU实现直接序列扩频系统数字化的方法,阐述了各部分电路的设计思路,给出了系统总体框图及实验系统的信号波形。     

数据异常值检测及修正方法研究

针对雷达测量数据中存在的异常值,对数据中的时间参数根据其变化规律的等差性进行异常值检测。对雷达发射功率、角度、距离参数异常问题,基于邻近去最值均值滤波原理,采用滑窗方式进行检测并修正。实验结果表明,提出的检测方法能够有效检测并修正数据中的异常跳变点且不改变正常值。     

激光冲击成形钛合金板料W形曲面的质量改进研究

实验以TA2钛合金板料作为试样,研究了激光冲击成形W形曲面的变形特点,分析了曲面底部产生微小鼓包的原因.为了改进成形面质量,提出了在板料与模具之间放置弹性垫,并对使用弹性垫的激光冲击成形W形曲面进行了数值模拟研究.结果表明,激光冲击与模具结合可以实现板料的W形曲面成形,W形面底部基本平整,但有微小鼓包;使用弹性垫可以抑制小鼓包的产生,能显著改善W形曲面的成形质量,使受冲击区域更加光滑.     

大型转台的力学仿真和结构优化设计

对大型一维测试系统转台的平台结构进行了强度刚度仿真分析,发现在偏心负载的情况下,局部变形大,应力集中问题突出,存在一定的安全隐患.通过在平台底面设置圆形轨道,并在轨道的8个均布位置设置非线性弹性支承轮提供支撑力,优化了整个平台的受力情况,改变了钢平台在工作中所受的约束条件,大大提高了其动力学特性,保障了转台的安全平稳运行.     

Carbon Metabolism of a Soilborne Mn(II)-Oxidizing Escherichia coli Isolate Implicated as a Pronounced Modulator of Bacterial Mn Oxidation

Mn(II)-oxidizing microorganisms are generally considered the primary driving forces in the biological formation of Mn oxides. However, the mechanistic elucidation of the actuation and regulation of Mn oxidation in soilborne bacteria remains elusive. Here, we performed joint multiple gene-knockout analyses and comparative morphological and physiological determinations to characterize the influence of carbon metabolism on the Mn oxide deposit amount (MnODA) and the Mn oxide formation of a soilborne bacterium, Escherichia coli MB266. Different carbon source substances exhibited significantly varied effects on the MnODA of MB266. A total of 16 carbon metabolism-related genes with significant variant expression levels under Mn supplementation conditions were knocked out in the MB266 genome accordingly, but only little effect on the MnODA of each mutant strain was accounted for. However, a simultaneous four-gene-knockout mutant (namely, MB801) showed an overall remarkable MnODA reduction and an initially delayed Mn oxide formation compared with the wild-type MB266. The assays using scanning/transmission electron microscopy verified that MB801 exhibited not only a delayed Mn-oxide aggregate processing, but also relatively smaller microspherical agglomerations, and presented flocculent deposit Mn oxides compared with normal fibrous and crystalline Mn oxides formed by MB266. Moreover, the Mn oxide aggregate formation was highly related to the intracellular ROS level. Thus, this study demonstrates that carbon metabolism acts as a pronounced modulator of MnODA in MB266, which will provide new insights into the occurrence of Mn oxidation and Mn oxide formation by soilborne bacteria in habitats where Mn(II) naturally occurs.     

碳酸二甲酯的合成方法研究

介绍了碳酸二甲酯的物理化学性质及其应用前景,详细综述了已经工业化和即将工业化的碳酸二甲酯的多种合成方法的基本原理及技术进展.     

Chl1, an ATP-Dependent DNA Helicase,Inhibits DNA:RNA Hybrids Formation at DSB Sites to Maintain Genome Stability in S. pombe

As an ATP-dependent DNA helicase, human ChlR1/DDX11 (Chl1 in yeast) can unwind both DNA:RNA and DNA:DNA substrates in vitro. Studies have demonstrated that ChlR1 plays a vital role in preserving genome stability by participating in DNA repair and sister chromatid cohesion, whereas the ways in which the biochemical features of ChlR1 function in DNA metabolism are not well understood. Here, we illustrate that Chl1 localizes to double-strand DNA break (DSB) sites and restrains DNA:RNA hybrid accumulation at these loci. Mutation of Chl1 strongly impairs DSB repair capacity by homologous recombination (HR) and nonhomologous end-joining (NHEJ) pathways, and deleting RNase H further reduces DNA repair efficiency, which indicates that the enzymatic activities of Chl1 are needed in Schizosaccharomyces pombe. In addition, we found that the Rpc37 subunit of RNA polymerase III (RNA Pol III) interacts directly with Chl1 and that deletion of Chl1 has no influence on the localization of Rpc37 at DSB site, implying the role of Rpc37 in the recruitment of Chl1 to this site.