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961.
S Kangsadalampai M Coggan SH Caglayan G Aktuglu PG Board 《Canadian Metallurgical Quarterly》1996,76(6):879-882
Deficiency of the A subunit of coagulation factor XIII causes a severe bleeding disorder requiring life long replacement therapy. The mutations causing A subunit deficiency appear to be very heterogeneous, and it is impractical to identify each mutation before genetic counselling or prenatal diagnosis can be attempted. In this study we have shown that a highly polymorphic short tandem repeat element, HUMF13A01 (AAAG)n that occurs in the 5' flanking sequence of the factor XIII A subunit gene, can be used to follow the segregation of deficiency causing mutations. We studied 6 families with factor XIII A subunit deficiency from 5 different ethnic groups. All parents were heterozygous for the repetitive element and therefore all the families were informative. The linked polymorphism was used to carry out the first prenatal diagnosis of factor XIII A subunit deficiency. The analysis of this polymorphism by the polymerase chain reaction is rapid, reliable, requires little DNA and is ideal for the genetic analysis of factor XIII A subunit deficiency. 相似文献
962.
S Murakami H Yokomizo S Matsushita M Ogawa Y Nishimura 《Canadian Metallurgical Quarterly》1996,49(3):149-153
We investigated retrospectively 132 cases of open wedge high tibial osteotomy using an external fixation device, concentrating on the rate of neurological complications. One group of patients underwent surgery according to the conventional technique (n = 89). The rate of transient neurological complications was 15.7%; 7 months after surgery the rate of persistent deficits was 12.4%. For the second group (n = 43) a modified surgical technique was used that lowered the complication rate significantly (transient deficits 14%, persistent deficits 4.7%). In the modified technique the osteotomy is not performed in the conventional way using an oscillating saw but through consecutive drill holes of increasing diameter followed by osteoclasis. The lower complication rate in the second group is mainly due to the less extensive approach that leads to a smaller number of postoperative tibialis anterior syndromes (type B lesion). No differences were found with type C lesions (extension deficit of D1). No complete peroneal nerve palsy (type A) occurred in either group. We conclude that the reduction of neurological complications in group 2 is related to the less extensive approach of the proposed technique. 相似文献
963.
Neusser S. Nijhuis J. Spaanenburg L. Hoefflinger B. Franke U. Fritz H. 《Micro, IEEE》1993,13(1):57-66
A solution to autonomous lateral vehicle guidance using a neurocontroller that can learn from measured human-driving data without knowledge of the physical car parameters is discussed. Simulations and practical tests confirm that a small-size feedforward autonomous neural network (21 neurons) can learn to steer a vehicle at high speeds only from looking at human-driving examples. In this way, the network learns the total closed-loop behavior, including the nonlinear dynamics of the vehicle and the driver's individual driving style. The main result of practical investigations is that the neutral controller trained on human-driving examples exhibits an aperiodic behavior that does not vanish at higher speeds (tests performed up to 130 km/h) and produces fewer lateral deviations than the linear state controller 相似文献
964.
A technique for SiO2 formation by liquid-phase deposition (LPD) at nearly room temperature for low-temperature processed (LTP) polysilicon thin-film transistor (poly-Si TFT) was developed. LPD SiO2 film with a lower P-etch rate shows a dense structure. LPD SiO2 also exhibits good electrical characteristics. LTP poly-Si thin-film transistors (TFTs) with LPD SiO 2 as the gate insulator have been fabricated and investigated. Their characteristics indicate performance adequate for their use as pixel transistors in liquid crystal displays (LCDs) 相似文献
965.
A Shanmugam C Copie-Bergman S Caillat JF Bach E Tournier-Lasserve 《Canadian Metallurgical Quarterly》1995,59(1-2):165-172
The role of myelin basic protein (MBP) T cell recognition in the induction of experimental allergic encephalomyelitis (EAE) has been well established in mice and rats. A remarkable restriction has been observed in T cell receptor (TCR) genes utilized by encephalitogenic T cell lines (TCLs) specific for immunodominant epitopes in these species. Pathological similarities between this animal model and multiple sclerosis (MS) has led to consider MBP as a major candidate autoantigen in this human disorder. Unlike in inbred strains of animals, the T cell response to MBP in humans is quite heterogenous with regard to fine epitope specificity. The existence of V alpha and/or V beta restriction in MBP-specific T cells, from MS patients and healthy controls, is still a matter of debate. In this study we generated 77 MBP-specific TCLs from nine healthy donors and showed that peptide 7-27 is one of the most frequently recognized epitopes. 37% of all epitope-specific TCLs recognized this peptide and p7-27 specific TCLs were generated from seven out of the nine subjects studied. A high level of in vivo clonal expansion was observed in p7-27-specific TCLs in several subjects, which however is not specific of this epitope since this phenomenon was also observed in p85-104- and 149-162-specific TCLs. 相似文献
966.
A new construction for the rotor windings of balanced wound-rotor induction motors employed in the slip energy recovery drives is proposed, in this paper, to reduce the time harmonics which are commonly generated in the machine. The proposed machine has a double-circuit in the rotor. One circuit is star connected while the other is delta connected. Each of these two circuits is connected to a diode-bridge rectifier to achieve a twelve-pulse operation characteristics. The main objective of this paper is to develop a new model which is capable of simulating the proposed machine, neglecting nonlinearities due to magnetic saturation, and its associated converters. Such a model is further complicated due to the presence of the two rotor circuits and their mutual interaction 相似文献
967.
A. E. Bohe J. J. Andrade Gamboa E. M. Lopasso D. M. Pasquevich 《Journal of Materials Science》1996,31(13):3469-3474
A chlorination process for recovering Zr from zircaloy scrap has been studied. Zircaloy chlorination was possible at temperatures as low as 220 °C. The scale microstructure and its effect on the zircaloy reactivity was analysed using Thermogravimetric analysis (TGA), X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDXS) and scanning electron microscopy (SEM) techniques. A solid-solid phase transformation took place into the oxide scale during the zircaloy chlorination. Zirconium, as ZrCl4(g), was separated from the oxide scale and chlorides of Cr and Fe. The effect of the reaction temperature was also analysed. 相似文献
968.
Design-quality metrics that are being developed for predicting the potential quality and complexity of the system being developed are discussed. The goal of the metrics is to provide timely design information that can guide a developer in producing a higher quality product. The metrics were tested on projects developed in a university setting with client partners in industry. To further validate the metrics, they were applied to professionally developed systems to test their predictive qualities. The results of applying two design metrics and a composite metric to data from a large-scale industrial project are presented 相似文献
969.
Arithmetic coding for data compression 总被引:17,自引:0,他引:17
Howard P.G. Vitter J.S. 《Proceedings of the IEEE. Institute of Electrical and Electronics Engineers》1994,82(6):857-865
Arithmetic coding provides an effective mechanism for removing redundancy in the encoding of data. We show how arithmetic coding works and describe an efficient implementation that uses table lookup as a first alternative to arithmetic operations. The reduced-precision arithmetic has a provably negligible effect on the amount of compression achieved. We can speed up the implementation further by use of parallel processing. We discuss the role of probability models and how they provide probability information to the arithmetic coder. We conclude with perspectives on the comparative advantages and disadvantages of arithmetic coding 相似文献
970.
Polyarteritis nodosa is a rare disorder and a form of systemic vasculitis. A 48 year-old female was admitted to the hospital because menorrhagia and pelvic pain in February 1993. The patient underwent exploratory laparotomy resulting in a total hysterectomy and bilateral salpingo-oophorectomy for myoma of uterus and a right adnexal cystic mass. Histopathologic examination revealed left ovarian periarteritis nodosa. Further investigation and 9 months follow-up failed to show any systemic involvement. To our knowledge the isolated ovarian polyarteritis nodosa is the first case in the literature. 相似文献