Removal of alkylphenols and polybromodiphenylethers by a biofiltration treatment plant during dry and wet-weather periods

This paper investigates the occurrence of alkylphenols (APs) and polybromodiphenylethers (PBDEs) in raw wastewater during dry and wet-weather periods, and their removal by physico-chemical lamellar settling and biofiltration techniques. Due to in-sewer deposit erosion and, to a lesser extent, to external inputs, raw effluents exhibit from 1.5 to 5 times higher AP and PBDE concentrations during wet periods compared with dry ones. The lamellar settler obtains high removal of APs and PBDEs under both dry and wet-weather flows (>53% for Σ(6)AP and >89% for Σ(4)PBDE), confirming the insensitivity of this technique to varying influent conditions. Indeed, despite the higher pollutant concentrations observed in raw effluents under wet-weather flows, adjusting the addition of coagulant-flocculent allows for efficient removal. By combining physical and biological processes, the biofiltration unit treats nutrient pollution, as well as Σ(6)AP and Σ(4)PBDE contamination (58 ± 5% and 75 ± 6% respectively). Although the operating conditions of the biofiltration unit are modified during wet periods, the performance in nutrient pollution, APs and light PBDE congeners remains high. Nevertheless, lower efficiency has been noted in nitrogen pollution, i.e. no denitrification occurs, and BDE-209 (not removed during wet-weather periods). In conclusion, this study demonstrates that the combination of both techniques treats AP and PBDE pollution efficiently during dry periods, but that they are also suitable for stormwater treatment.     

Inhibition of HeLa cell messenger RNA translation by 7-methylguanosine 5'-monophosphate

Translation of HeLa cell RNA containing poly(A) in a wheat germ cell-free system is markedly but incompletely inhibited by 7-methylguanosine 5'-monophosphate (m7G5'p). We have analyzed the translation products synthesized in the presence of different concentrations of m7G5'p and find that translation of all mRNAs is equally inhibited. To demonstrate the specificity of the inhibitor for RNAs with 5'-terminal m7G5' ppp... we show that specific translation products of satellite tobacco necrosis virus RNA, which does not have this 5' terminus, are synthesized in the presence of m7G5' p. Protein synthesis programmed by endogenous mRNA in a HeLa cell-free system is inhibited after a 10-min lag by m7G5' p. Other guanosine nucleotides without the 7-methyl group or with the phosphate in a different position are not inhibitor. We show that translation of all mRNAs is inhibited to a similar extent by m7G5'p in the HeLa cell-free system, by synthesizing 35S-labeled proteins in the presence of different inhibitory concentrations of this nucleotide and analyzing the translation products by electrophoresis and autoradiography. Translation of encephalomyocarditis virus RNA added to the HeLa cell-free system is not inhibited by m7"g5p; this viral RNA does not have this nucleotide at the 5' terminus. This indicates that m7G5'p specifically inhibits translation of mRNAs with the 5' terminus m7G5'ppp... and suggests that initiation of translation of picornavirus RNA may proceed via a mechanism different from that of cellular mRNAs.     

Occurrence of gastric ulcer after Nissen fundoplication

Of 160 patients who underwent Nissen fundoplication for treatment of symptomatic peptic reflux esophagitis, five patients (3.1%) developed gastric ulcers. Four of these five patients experienced the "gas-bloat" syndrome. All ulcers were located on the lesser curvature of the stomach. Analyses of our experience with use of various types of hiatal hernia repair suggests that creation of the valvuloplastic mechanism unique to the Nissen procedure may be of etiologic significance in the development of gastric ulcers following this procedure.     

Perforating pseudoxanthoma elasticum. Its distinction from elastosis perforans serpiginosa

It is not generally appreciated that pseudoxanthoma elasticum (PXE) can be associated with epidermal perforation by elastic fibers. We report an example of this phenomenon. The term "perforating PXE" is suggested and a distinction is made from elastosis perforans serpiginosa (EPS). We believe that most reported cases of coexistence of PXE and EPS are perforating PXE and that the coexistence of EPS has not been clearly demonstrated.     

Measurements and simulations of transient characteristics of heat pipes

The rejection of heat generated by components and circuits is a very important aspect in design of electronics systems. Heat pipes are very effective, low cost elements, which can be used in cooling systems. This paper presents the modelling and measurements of the heat and mass transfer in heat pipes. The physical model includes the effects of liquid evaporation and condensation inside the heat pipe. The internal vapour flow was fully simulated using computational fluid dynamics. The theory has been compared with experimental measurements using thermographic camera and contact thermometers. The main purpose of this study is to determine the effective heat pipe thermal conductivity in transient state during start up the pipe operation and temperature increase.     

Tuning of PI controllers with one-way decoupling in 2×2 MIMO systems based on finite frequency response data

A method of tuning for PI controllers with one-way lead/lag decoupling tuning is demonstrated for 2×2 input-output systems, based on finite frequency response data. The frequency response estimates are obtained from closed loop tests using an identification technique based on bandpass filters. The open-loop frequency response is calculated and used to tune PI controllers and to fit lead-lag compensators for decoupling by weighted least-squares. Separate optimization of the PI controllers and the lead-lag compensator is preferred. The tuning takes into account violations of desired multivariable robustness criteria. The method is illustrated by application to a paper machine headbox simulation and by experiments in distillation column temperature control.     

Practical implementation of possibilistic probability mass functions

 Probability assessments of events are often linguistic in nature. We model them by means of possibilistic probabilities (a version of Zadeh's fuzzy probabilities with a behavioural interpretation) with a suitable shape for practical implementation (on a computer). Employing the tools of interval analysis and the theory of imprecise probabilities we argue that the verification of coherence for these possibilistic probabilities, the corrections of non-coherent to coherent possibilistic probabilities and their extension to other events and gambles can be performed by finite and exact algorithms. The model can furthermore be transformed into an imprecise first-order model, useful for decision making and statistical inference.     

Scheduling and Lot Streaming in Flowshops with No-Wait in Process

Lot streaming involves splitting a production lot into a number of sublots, in order to allow the overlapping of successive operations, in multi-machine manufacturing systems. In no-wait flowshop scheduling, sublots are necessarily consistent, that is, they remain the same over all machines. The benefits of lot streaming include reductions in lead times and work-in-process, and increases in machine utilization rates. We study the problem of minimizing the makespan in no-wait flowshops producing multiple products with attached setup times, using lot streaming. Our study of the single product problem resolves an open question from the lot streaming literature. The intractable multiple product problem requires finding the optimal number of sublots, sublot sizes, and a product sequence for each machine. We develop a dynamic programming algorithm to generate all the nondominated schedule profiles for each product that are required to formulate the flowshop problem as a generalized traveling salesman problem. This problem is equivalent to a classical traveling salesman problem with a pseudopolynomial number of cities. We develop and computationally test an efficient heuristic for this problem. Our results indicate that solutions can quickly be found for flowshops with up to 10 machines and 50 products. Moreover, the solutions found by our heuristic provide a substantial improvement over previously published results.     

Modeling Fully Depleted SOI MOSFETs in 3D Using Recursive Scattering Matrices

As the semiconductor industry pushes towards ever decreasing device sizes, the need for an efficient yet accurate simulation method increases. We present a different approach to modeling ultra small semiconductor devices through the use of recursive scattering matrices. This approach is a completely quantum mechanical approach in three dimensions, yet does not suffer from excessive computation time or resources. While the transport in most small semiconductor devices is typically 2D in nature, with a 3D model we are capable of incorporating the interaction of the 3D modes in the contacts with the 2D modes in the active regions. We demonstrate this approach by presenting results for a short channel fully-depleted SOI (Silicon On Insulator) MOSFET. We present results using both hardwall potentials and self-consistent potentials as calculated through the use of an iterative Poisson solver.     

Integrating CAD tools for MEMS design

Microelectromechanical systems, or MEMS, is the generic name for a new class of microsystems. Typically, MEMS are: micron- to millimeter-scale devices with moving parts or containing fluids; parts that are batch fabricated using techniques derived from the semiconductor industry; used as sensors or actuators; and are often directly connected or integrated with ICs. The first MEMS design system, MEMCAD, was built in the Senturia Lab at MIT. Now at least three companies market commercial CAD systems for MEMS. The author discusses MEMCAD system's capabilities