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571.
Thorsten Falk Ralf Heese Christian Kaspar Malgorzata Mochol Daniel Pfeiffer Michael Thygs Robert Tolksdorf 《Informatik-Spektrum》2006,48(1):201-209
The importance of the Internet for job procurement is increasing for the reason that three quarters of the people in the employment
age are online. On the other hand because ever more companies are publishing their job offers on the Web. However, due to
the large number of openings published online it is almost impossible for job seekers and job portals to gain an overview
of the entire employment market. Since job offers lack semantically meaningful annotations, the search and integration into
databases are made highly difficult. Applying Semantic Web technologies to the e-recruitment process provides advantages for
all participants in the market. In this paper we describe a method for analysing the domain-specific language of an application
domain. We use this method to describe the e-recruitment process and the necessary ontologies for annotating job offers and
job applications. In conclusion, we present the prototypical implementation of the scenario based on Semantic Web, especially
semantic matching. 相似文献
572.
N Pfeiffer 《Canadian Metallurgical Quarterly》1997,42(2):137-151
Systemic carbonic anhydrase inhibitors are among the most powerful agents to lower intraocular pressure. Unfortunately, their use is frequently accompanied by undesired side effects. Some are due to the relatively large amounts of drug that have to be systemically administered to inhibit the carbonic anhydrase in the ciliary processes. Recently, dorzolamide, a topical carbonic anhydrase inhibitor, has become commercially available for clinical use. This article reviews the development of topical carbonic anhydrase inhibitors with special reference to dorzolamide. When administered three-times daily, dorzolamide lowers intraocular pressure in a clinically useful manner. Ocular side-effects include frequent stinging and burning and allergy can develop. Systemic side effects have not been observed that could definitively be related to inhibition of extraocular carbonic anhydrase. Blood dyscrasias have not yet been observed. Absence of cardiovascular and pulmonary side effects, as can occur with beta adrenergic antagonists, and lack of pupillary and accommodative stimulation, as occur with cholinergic agonists, might make dorzolamide first-line medical treatment for elevated intraocular pressure. 相似文献
573.
We present in this paper a compilation of the present status of experimental delayed-neutron precursor data; i.e. β-decay half-lives (T1/2) and neutron emission probabilities (Pn) in the fission-product region (27 ≤ Z ≤ 57). These data are compared to two model predictions of substantially different sophistication: (i) an update of the empirical Kratz-Herrmann formula (KHF), and (ii) a unified macroscopic-microscopic model within the quasi-particle random-phase approximation (QRPA). Both models are also used to calculate so far unknown T1/2 and Pn values up to Z = 63. A number of possible refinements in the microscopic calculations are suggested to further improve the nuclear-physics foundation of these data for reactor and astrophysical applications. 相似文献
574.
575.
G. Schwartz M. Pfeiffer S. Reineke K. Walzer K. Leo 《Advanced materials (Deerfield Beach, Fla.)》2007,19(21):3672-3676
576.
HPLC quantification of major active components from 11 different saffron (Crocus sativus L.) sources
Heriberto Caballero-Ortega Rogelio Pereda-Miranda Fikrat I. Abdullaev 《Food chemistry》2007,100(3):1126-1131
Eleven certified saffron samples (Crocus sativus L.), one each from Azerbaijan, China, Greece, France, India, Iran, Italy, New Zealand, Spain, Turkey and the Sigma Chemical Company, were analyzed by using an HPLC photodiode array detection method. This analysis quantified the 10 major saffron compounds in each sample and their concentration was analyzed at three different wavelengths. Results indicated that the Greek, Indian, New Zealand, and Spanish saffron extracts possessed the highest concentrations of water-soluble glycosidic carotenoids (?8.0%) suggesting that they could be a good source of this type of metabolites for further biological evaluation. 相似文献
577.
The Haseltalbridge near Suhl – final design, fabrication and erection. The article describes the execution of the new Haseltal bridge near Suhl/Germany through the phases of final design, fabrication and erection under consideration of the complex local requirements. 相似文献
578.
In cultured cells, curcumin (CUR) causes cell death by interfering with mitosis and leading to fragmented nuclei and disrupted microtubules, a process named mitotic catastrophe. In order to clarify the role of the known CUR metabolites hexahydro-CUR (HHC) and CUR-glucuronide (CUR-gluc) in mitotic catastrophe, the effects of CUR were studied in three human cancer cell lines with different metabolism of CUR. In Ishikawa and HepG2 cells, CUR was metabolized to HHC and small amounts of octahydro-CUR (OHC), whereas the only metabolism in HT29 cells was the formation of CUR-gluc. Despite their different metabolism, all three cell systems responded to CUR with arrest in G2/M phase and mitotic catastrophe. Fractionation of the cells showed that concentrations of CUR were higher in the ER and cytosol than in the incubation medium by a factor of up to about 150 and 8, respectively. In contrast to CUR, the metabolite HHC and the products of spontaneous degradation did not elicit any effects in Ishikawa cells. These results imply that the causative agent of mitotic catastrophe is the parent CUR molecule, whereas reductive metabolism and chemical degradation render CUR inactive. 相似文献
579.
Shastri Y Diwekar U Cabezas H Williamson J 《Environmental science & technology》2008,42(17):6710-6716
Successful implementation of sustainability ideas in ecosystem management requires a basic understanding of the often nonlinear and nonintuitive relationships among different dimensions of sustainability, particularly the system-wide implications of human actions. This basic understanding further includes a sense of the time scale of possible future events and the limits of what is and is not likely to be possible. With this understanding, systematic approaches can then be used to develop policy guidelines for the system. This article presents an illustration of these ideas by analyzing an integrated ecological-economic-social model, which comprises various ecological (natural) and domesticated compartments representing species along with a macroeconomic price setting model. The stable and qualitatively realistic model is used to analyze different relevant scenarios. Apart from highlighting complex relationships within the system, it identifies potentially unsustainable future developments such as increased human per capita consumption rates. Dynamic optimization is then used to develop time-dependent policy guidelines for the unsustainable scenarios using objective functions that aim to minimize fluctuations in the system's Fisher information. The results can help to identify effective policy parameters and highlight the tradeoff between natural and domesticated compartments while managing such integrated systems. The results should also qualitatively guide further investigations in the area of system level studies and policy development. 相似文献
580.
The lure of video blogging combines the ubiquitous, grassroots, Web-based journaling of blogging with the richness of expression available in multimedia. Some claim that video blogging is an important force in a future world of video journalism and a powerful technical adjunct to our existing televised news sources. Others point to the huge demands it imposes on networking resources, the lack of hard standards, and the poor usability of current video blogging systems as indicators that it's doomed to fail. Like any nascent technology, video blogging has many unsolved problems. The field, however, is vibrant, the goals are fairly clear, and the challenges they pose to multimedia researchers are exciting indeed. Developing the standards and technologies for video blogging requires a combination of approaches from various areas including media representation, information retrieval, multimedia content analysis, and video summarization. Like the development of the Web and text blogging before, video blogging only come about through open development and collaboration between engineers and researchers from diverse fields. Most strikingly, it is fueled by the passion and enthusiasm of those creating content - those who go to the trouble of recording their lives and opinions within the fledgling medium, shaping it as a lively and useful resource for generations of Internet users to come. 相似文献