Effects of species and moisture content on penetration of liquid in laser incised lumber by the passive impregnation method

Penetration of liquid by passive impregnation method for Douglas-fir (Pseudotsuga menziesii Franco), sugi (Cryptomeria japonica D. Don) and Japanese larch (Larix leptolepis Gordon) was studied. Effects of initial moisture content of sugi (16, 43 and 70% moisture content) on liquid penetration were also studied. Dried Douglas-fir (mc=14%) and sugi (mc=16%), and green Japanese larch (mc=45%) and sugi (mc=70%) were treated by passive impregnation method for penetration analysis. It was observed that dried sugi had the highest level of liquid penetration both in length (170 mm) and width (8 mm) for all measured sections followed by green sugi, green Japanese larch and dried Douglas-fir. In case of different initial moisture content, the highest absorption (624 kg/m³) and penetration (maximum 87 and 96% at cross and longitudinal surfaces, respectively) was observed for sugi having the lowest initial moisture content under the same passive impregnation conditions. Absorption and penetration decreased with the increase of initial moisture content for sugi. These results could help in designing incising pattern and density, as well as solving the problems related to high initial moisture content of wood for passive impregnation.     

High-performance polymer photovoltaic devices with inverted structure prepared by thermal lamination

Use of a lamination process for the introduction of Au electrode, instead of conventional metal evaporation, improved the power conversion efficiency (PCE) of inverted-structure photovoltaic devices from 1.6% to 2.6% based on a bulk heterojunction of poly(3-hexylthiophene) (P3HT) and (6,6)-phenyl C₆₁ butyric acid methyl ester (PCBM). X-ray photoelectron spectroscopy indicated that a thin layer of P3HT is spontaneously formed at the air/polymer blend layer interface during the spin-coating process. It is suggested that the vacuum-evaporated gold could destroy the surface-segregated thin layer of P3HT, while the lamination process preserves the surface structure working as an electron-blocking layer. The insertion of a PEDOT:PSS layer, between the metal electrode and polymer layer, in the lamination process further improved the PCE to 3.3% with a short-circuit current density of 9.94 mA cm⁻², an open-circuit voltage of 0.60 V, and a fill factor of 55% under AM1.5 100 mW cm⁻² irradiation.     

Induced bone by calcium ohosphate (Ca-P) ceramics after 2-years implantation

The changes of induced bone with four kinds of Ca-P ceramics after 2 years implantation in the dorsal muscles of rabbits were investigated. After 2 years implantation, mature bone (with a lamellar structure after the remodeling process) with bone marrow was observed in HA1100 (HA, micro+macro porous), HA900 (HA, micro+macro porous) and BCP (HA/TCP=7:3, micro+ macro porous), and no bone formation was observed in HA1200 (HA, macro porous) ceramics. The induced bone neither disappeared nor grew uncontrollably, and was seen inside the pores of the implants or on the outer surface under the fibrous layer after 2 years. No bone formation was observed in the soft tissues distant from the implants. These results indicate that heterotopic bone formation induced by Ca-P materials did not give rise to uncontrolled growth over time, and the induced bone is limited to the inside or around the implants. Moreover, ectopic bone formation on the outer surface of the implants was detected in rabbits after 2 years.     

FDTD simulation of nonlinear ultrasonic pulse propagation in ESWL using equations including Lagrangian

A new FDTD algorithm is proposed for analyzing ultrasonic pulse propagation in the human body, a problem connected with ESWL (extracorporeal shock wave lithotripsy). In this method, we do not use plane wave approximation but directly employ the original equations, taking into account the Lagrangian to derive new FDTD algorithms. This method is applied to an experimental setup and its numerical model that resembles an actual treatment situation in order to compare the sound pressure distributions obtained numerically with those obtained experimentally. The present method is shown to give clearly better results than the earlier method, from the point of view of the numerical reappearance of a strongly nonlinear waveform. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 169(4): 29–36, 2009; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/eej.20819     

Short‐span seeking control of hard disk drive with vibration suppression PTC

In a short‐span seeking‐mode of hard disk drives, the resonance modes are getting crucial obstruction to meet the demand on high‐speed data access. In this paper, a novel vibration suppression perfect tracking control (PTC) method is proposed based on controllable canonical realization. In the proposed method, it is assumed that the plant is modeled as the rigid and primary resonance mode. By using this model, the feed forward controller is designed with PTC by multirate sampling control in order to suppress the primary vibration. Additionally, the higher‐order resonance vibration is attenuated by using the trajectory MHVT. The proposed method achieved 16% faster seeking than MPVT, a conventional method. © 2007 Wiley Periodicals, Inc. Electr Eng Jpn, 162(1): 66–72, 2008; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/eej.20546     

N-Alkylation of chitin and some characteristics of the novel derivatives

Summary Introduction of simple alkyl groups at the C-2 nitrogen of chitin and some properties of the resulting N-alkyl-chitins have been examined. Chitosan was fully deacetylated and treated with three kinds of aldehydes, formaldehyde, acetaldehyde, and pentanal. The Schiff bases of chitosan, whose extents of substitution were dependent on the amount of aldehydes, were reduced with sodium cyanoborohydride to N-alkylated chitosans. The N-alkyl-chitosans were then transformed into the corresponding N-alkyl-chitins by acetylation with acetic anhydride followed by transesterification to remove partly formed O-acetyl groups. The resulting N-methyl-, ethyl-, and pentyl-chitins were amorphous and showed improved affinity for organic solvents. Received: 13 December 2001/Revised version: 11 January 2002/Accepted: 17 January 2002     

Limited sampling model for the area under the concentration versus time curve of irinotecan and its application to a multicentric phase II trial

We previously established a limited sampling model (LSM) for the area under the concentration versus time curve (AUC) of irinotecan (CPT-11). Using this LSM, we performed a pharmacokinetic-pharmacodynamic analysis of CPT-11 in a multicentric Phase II study for non-small cell lung cancer. Ten institutes participated in this study, 36 patients were registered, and 30 patients were evaluable for the pharmacokinetic-pharmacodynamic analysis. CPT-11 and etoposide were administered daily for three consecutive days, both at a dose of 60 mg/m2. Blood samples were obtained 4 and 8 h after infusion on days 1 and 3. When using the LSM, there is a significant possible source of error in the timing of these selected points. In this study, however, the sample timing error was small. Mean timing errors were 1.0-4.0 min at each point. The estimated CPT-11 AUCs were: Day 1 Day 2 Day 1 + 3 Mean +/- SD (mg.h/liter) 3.76+/-0.68 4.10+/-0.86 7.86+/-1.43 Range 2.01-5.03 2. 29-5.72 4.30-10.68 Max/min 2.50 2.45 2.48 High interpatient variability was observed in the AUC. The CPT-11 AUC correlated positively with the grade of emesis (P = 0.003) and the percent decreases in WBC count (P = 0.001) and absolute neutrophil count (P =0.0006), but it did not correlate with the grade of diarrhea or response. We concluded that the LSM was useful in estimating individual pharmacokinetic parameters in multicentric trials.     

The JUSTSAP experiment on STS-95

An instrumented flow cell in the form of a cylinder with differentially heated end walls and adiabatic sidewalls was flown on STS-95 as the Japan-US Thermal Science Accelerometer Project (JUSTSAP). The purpose of the experiment was to map disturbances in the thermal field during the course of a Shuttle mission in order to correlated them with various mission events and to determine if any global transport could be detected from second order, non-zero time average flows resulting from periodic accelerations (g-jitter). Significant disturbances in the thermal field were noted each time the Shuttle changed attitude, such as the maneuver to -Z solar inertial, which is done periodically for thermal conditioning. Burns from the main thrusters associated with the launch and retrieval of the Spartan satellite produced overturning flows, as might be expected. During extended periods in which the attitude was held constant, the perturbations to the thermal field correlate extremely well with calculated accelerations from gravity gradient and drag. Fair agreement was found between the observed temperature perturbations and those predicted from a modification of the analytical model developed by Bejan and Tien (B&T) for the flow and heat transfer in an infinite cylinder with a constant axial thermal gradient. A full three-dimensional computational fluid dynamic analysis with more realistic thermal boundary conditions provided better agreement after adjustments were made to account for the heat flow away from the measuring thermistors. Once calibrated with a reliable thermal model, the flow cell was found to serve as a high-precision accelerometer, capable of measuring the quasi-steady acceleration with a sensitivity of better than 0.1 micro-g in the presence of the higher amplitude g-jitter typical of Shuttle operations. Further, it was found that the gravity gradient acceleration accounted for virtually all of the observed quasi-steady accelerations during such extended periods. The thermal response time of the JUSTSAP was too slow to expect to see the effects of fluctuating first order flows resulting from the vibrational environment of the Shuttle. However, an indication of a change in the thermal field near the ends of the flow cell was seen during periods of crew exercise that may possibly be attributed to circulating eddies resulting from the higher order terms in the momentum equation. At higher amplitudes, these second order effects can produce non-zero time average flows of a global nature, as can the start-up transients in first-order periodic flows. No such effects were observed, thus it is possible to place an upper limit on the integrated power spectral density of the vibrational environment experienced as well as the nature of the start-up transients of the periodic flows.     

Polymer-electrolyte water electrolysis

The electricity for the electrolyzer is supplied by a variable electricity supply unit that simulates actual outputs of both series and parallel combinations of solar cells exposed to various solar intensities. An amorphous-silicon solar cell is used as a sensor for the unit The operation was continued for more than 600 days without trouble. The case of direct connection of the solar cell and polymer electrolyte (PE) water electrolyzer is simulated: the test results show that more than 95% of the peak electricity power of the solar battery can be utilized for the electrolyzer over various solar radiation conditions.     

Reconstitution of hepatic tissue architectures from fetal liver cells obtained from a three-dimensional culture with a rotating wall vessel bioreactor

Reconstitution of tissue architecture in vitro is important because it enables researchers to investigate the interactions and mutual relationships between cells and cellular signals involved in the three-dimensional (3D) construction of tissues. To date, in vitro methods for producing tissues with highly ordered structure and high levels of function have met with limited success although a variety of 3D culture systems have been investigated. In this study, we reconstituted functional hepatic tissue including mature hepatocyte and blood vessel-like structures accompanied with bile duct-like structures from E15.5 fetal liver cells, which contained more hepatic stem/progenitor cells comparing with neonatal liver cells. The culture was performed in a simulated microgravity environment produced by a rotating wall vessel (RWV) bioreactor. The hepatocytes in the reconstituted 3D tissue were found to be capable of producing albumin and storing glycogen. Additionally, bile canaliculi between hepatocytes, characteristics of adult hepatocyte in vivo were also formed. Apart from this, bile duct structure secreting mucin was shown to form complicated tubular branches. Furthermore, gene expression analysis by semi-quantitative RT-PCR revealed the elevated levels of mature hepatocyte markers as well as genes with the hepatic function. With RWV culture system, we could produce functionally reconstituted liver tissue and this might be useful in pharmaceutical industry including drug screening and testing and other applications such as an alternative approach to experimental animals.