Mechanical Property Investigation of Soft Materials by Cantilever‐Based Optical Interfacial Force Microscopy

Cantilever‐based optical interfacial force microscopy (COIFM) was applied to the investigation of the mechanical properties of soft materials to avoid the double‐spring effect and snap‐to‐contact problem associated with atomic force microscopy (AFM). When a force was measured as a function of distance between an oxidized silicon probe and the surface of a soft hydrocarbon film, it increases nonlinearly in the lower force region below ∼10 nN, following the Herzian model with the elastic modulus of ∼50 MPa. Above ∼10 nN, it increases linearly with a small oscillatory sawtooth pattern with amplitude 1–2 nN. The pattern suggests the possible existence of the layered structure within the film. When its internal part of the film was exposed to the probe, the force depends on the distance linearly with an adhesive force of −20 nN. This linear dependence suggests that the adhesive internal material behaved like a linear spring with a spring constant of ∼1 N/m. Constant‐force images taken in the repulsive and attractive contact regimes revealed additional features that were not observed in the images taken in the noncontact regime. At some locations, however, contrast inversions were observed between the two contact regimes while the average roughness remained constant. The result suggests that some embedded materials had spring constants different from those of the surrounding material. This study demonstrated that the COIFM is capable of imaging mechanical properties of local structures such as small impurities and domains at the nanometer scale, which is a formidable challenge with conventional AFM methods. SCANNING 35:59‐67, 2013. © 2012 Wiley Periodicals, Inc.     

Economic feasibility of energy efficiency measures in residential buildings

A study has been performed to develop cost benefit data to be used by a local electric utility in defining a rebate program to encourage energy efficient construction in the Desert Southwest region of the USA. Several potential efficiency upgrades for production homes in the region were identified and an evaluation of each building component was performed using building energy simulation software. A model home developed in Las Vegas was used to calibrate the numerical model and was considered as a basis for further study. The validated building models were then used to predict the annual energy savings and payback periods for various upgrades. In all cases, comparisons were made to code-built houses with the same general overall characteristics. Useful life of most of these upgrades far exceeds their payback periods. It is found that a typical house, with the cost-effective upgrades installed, consumed 42.5% less annual energy compared to a home built to code. A 3.19 kWp PV system installed on the south-facing roof of the home can generate 5982 kWh annually, making it a net-zero (electrical) energy home. PV systems in Las Vegas have encouraging benefit cost ratios when federal and state rebates are considered.     

Top 10 list [software development]

Software's complexity and accelerated development schedules make avoiding defects difficult. We have found, however, that researchers have established objective and quantitative data, relationships, and predictive models that help software developers avoid predictable pitfalls and improve their ability to predict and control efficient software projects. The article presents 10 techniques that can help reduce the flaws in your code     

Sensitivity to ethanol-induced motor incoordination in 5-HT1B receptor null mutant mice is task-dependent: Implications for behavioral assessment of genetically altered mice.

Neuromuscular impairment by ethanol likely involves complex effects on balance, gait, muscle strength, and other features of motor coordination. The present experiments showed that relative sensitivity to ethanol-induced motor impairment in serotonin 1B (5-HT1B) null mutant and control mice was task dependent. We found that ethanol-treated null mutant mice made fewer missteps on a balance beam than did ethanol-treated wild-type mice, and confirmed a previous finding of their lesser ethanol sensitivity in the grid test. The genotypes did not differ in ethanol sensitivity as measured by the screen test, static dowel, fixed-speed rotarod, accelerating rotarod, grip strength, or loss of righting reflex tests. These experiments suggest that within a behavioral domain, alternative tests of function are not equivalent, so multiple assessment tools should be used to avoid misinterpretation of gene function. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

High-temperature (T=490 K) operation of 5.8 /spl mu/m quantum cascade lasers with InP/GaInAs waveguides

5.8 /spl mu/m Ga/sub 0.4/In/sub 0.6/As/Al/sub 0.56/In/sub 0.44/As strain-compensated quantum-cascade lasers with InP and GaInAs cladding layers using solid-source molecular-beam epitaxy have been fabricated. Low threshold current densities and high-temperature operation of uncoated devices, with a record value of 490 K, have been achieved in pulsed mode.     

Inhibition of N-type calcium channels: the only mechanism by which presynaptic alpha 2-autoreceptors control sympathetic transmitter release

Alpha 2-Adrenoceptors are known to inhibit voltage-dependent Ca2+ channels located at neuronal cell bodies; the present study investigated whether this or alternative mechanisms, possibly downstream of Ca2+ entry, underlie the presynaptic alpha 2-adrenergic modulation of transmitter release from chick sympathetic neurons. Using chick sympathetic neurons, overflow of previously incorporated [3H]noradrenaline was elicited in the presence of extracellular Ca2+ by electrical pulses, 25 mM K+ or 10 microM nicotine, or by adding Ca2+ to otherwise Ca(2+)-free medium when cells had been made permeable by the calcium ionophore A23187 or by alpha-latrotoxin. Pretreatment of neurons with the N-type Ca2+ channel blocker omega-conotoxin GVIA and application of the alpha 2-adrenergic agonist UK 14304 reduced the overflow elicited by electrical pulses, K+ or nicotine, but not the overflow caused by Ca2+ after permeabilization with alpha-latrotoxin or A23187. In contrast, the L-type Ca2+ channel blocker nitrendipine reduced the overflow due to K+ and nicotine, but not the overflow following electrical stimulation or alpha-latrotoxin- and A23187-permeabilization. The inhibition of electrically evoked overflow by UK 14304 persisted in the presence of nitrendipine and the L-type Ca2+ channel agonist BayK 8644, which per se enhanced overflow. In omega-conotoxin GVIA-treated cultures, electrically evoked overflow was also enhanced by BayK 8644 and almost reached the value obtained in untreated neurons. However, UK 14304 lost its effect under these conditions. Whole-cell recordings of voltage-activated Ca2+ currents corroborated these results: UK 14304 inhibited Ca2+ currents by 33%, nitrendipine caused a 7% reduction, and BayK 8644 increased the currents by 30%. Moreover, the dihydropyridines failed to abolish the inhibition by UK 14304, but pretreatment with omega-conotoxin GVIA, which reduced mean amplitude from 0.95 to 0.23 nA, entirely prevented alpha 2-adrenergic effects. Our results indicate that the alpha 2-autoreceptor-mediated modulation of noradrenaline release from chick sympathetic neurons relies exclusively on the inhibition of omega-conotoxin GVIA-sensitive N-type Ca2+ channels. Mechanisms downstream of these channels and voltage-sensitive Ca2+ channels other than N-type appear not to be important.     

Value-based processes for COTS-based applications

Economic imperatives are changing the nature of software development processes to reflect both the opportunities and challenges of using COTS products. Processes are increasingly moving away from the time-consuming composition of custom software from lines of code (although these processes still apply for developing the COTS products themselves) toward assessment, tailoring, and integration of COTS or other reusable components. Two factors are driving this change: COTS or other reusable components can provide significant user capabilities within limited costs and development time, and more COTS products are becoming available to provide needed user functions.     

Selected equipment,materials, and process interactions in a surface-imaging process

The advantages of surface-imaging photoresist processes have been well documented; it has shown to have greater resolution, wider focus budget, and less sensitivity to topography and reflections from the substrate. The DESIRE process (Diffusion Enhanced Silylated Resist) is a good example of a surface-imaging process. In previous papers we have described the characterization of this process in a lab environment, discussed some of the issues involved in the implementation of this process in a manufacturing environment, and more recently presented results from its implementation in a dynamic random memory, DRAM, manufacturing environment. A large of knowledge must be acquired and disseminated in the process of implementing a new technology in a manufacturing environment. This is particularly true in the semiconductor industry because of the large and complex interactions that exist between the process and the electronic characteristics of the devices. Even within the same process, complex interactions between the different steps can take place. Such is the case with the DESIRE process. Over the past few years a great deal of “know-how” has been acquired in the course of implementing this technology in a DRAM wafer fab of Texas Instruments in Dallas, Tex. We present here two selected cases where such complex interactions have been investigated: (1) radiation damage that might take place during the dry-development step of this process, and (2) the effect of the equipment and material on the electrical discharge, or arcing, during dry-development.