Comparative study of soluble naphthalene diimide derivatives bearing long alkyl chains as n-type organic thin-film transistor materials

In this study, several naphthalene tetracarboxylic acid diimide (NTCDI) derivatives substituted at the N and N′ positions with long normal alkyl chains of different lengths were evaluated as soluble n-type organic thin-film transistor (TFT) materials. NTCDI derivatives with diundecyl (NTCDI-C11), didodecyl (NTCDI-C12), and ditridecyl (NTCDI-C13) exhibited acceptable solubility in chloroform, and their TFTs showed typical n-type TFT performance with relatively high field effect electron mobility (～0.2 cm²/V s) after annealing at a workable temperature of 150 °C. Although NTCDI with dioctyl (NTCDI-C8) showed good solubility in chloroform, the TFT performance of this material was highly inferior to that of NTCDI-C11, NTCDI-C12, or NTCDI-C13. We could not anneal NTCDI-C8 thin films at workable temperatures in vacuo because of sublimation of the material from the substrates. In contrast, NTCDI with dipentadecyl (NTCDI-C15) and dioctadecyl (NTCDI-C18) exhibited both poor solubility for chloroform and poor TFT performance. In short, these compounds are not suitable as soluble n-type organic TFT materials.     

Gain distribution measurement of an erbium-doped silica-based waveguide amplifier using a complex OLCR

We have measured the gain distributions of a 38-cm-long erbium-doped silica-based waveguide amplifier with different pump powers by using a complex optical low coherence reflectometer. The spatial resolution is /spl sim/5 mm and the noise level is /spl plusmn/1 dB. The measured distributions agree well with those derived from rate equations. We can estimate such amplifier parameters as the stimulated emission coefficient and the optimum waveguide length enabling us to achieve the maximum gain for any pump power.     

Seasonal profiles of human noroviruses and indicator bacteria in a wastewater treatment plant in Tokyo, Japan.

The seasonal profiles of microorganisms in raw sewage, secondary-treated sewage, and final effluent at a wastewater treatment plant in Tokyo, Japan, were quantitatively determined each month for one year, from July 2003 to June 2004. Human noroviruses, which were determined by real-time PCR, in raw sewage varied from 0.17-260 copies/mL for genotype 1 and from 2.4-1900 copies/mL for genotype 2, showing much higher values in winter, the epidemic season. The concentration of total coliforms, Escherichia coli, or F-specific phages in raw sewage was almost constant throughout the year. Human noroviruses of genotype 2 were removed most effectively (3.69 log10 on average) at the wastewater treatment plant, followed by E. coli (3.37 log10), total coliforms (3.05 loglo), F-specific phages (2.81 log10), and human noroviruses of genotype 1 (2.27 log10). The removal ratio of human noroviruses was almost constant, independent of the initial concentration of the viruses in raw sewage, which led to the increasing concentration of human noroviruses in final effluent in winter. None of the tested bacteria was judged to be a reliable indicator of human noroviruses in final effluent.     

Reversible Control of Exo‐ and Endo‐Budding Transitions in a Photosensitive Lipid Membrane

We have developed a method for the photomanipulation of lipid membrane morphology in which the shape of a vesicle can be switched by light through the use of a synthetic photosensitive amphiphile containing an azobenzene unit (KAON12). We prepared cell‐sized liposomes from KAON12 and 1,2‐dioleoyl‐sn‐glycero‐3‐phosphocholine (DOPC) and conducted real‐time observations of vesicular transformation in the photosensitive liposome by phase‐contrast microscopy. Budding transitions—either budding toward the centre of the liposome (endo‐bud) or budding out of the liposome (exo‐bud)—could be controlled by light. We discuss the mechanism of this transformation in terms of the change in the effective membrane surface area due to photoisomerization of the constituent molecules.     

Effects of rainfall on the occurrence of human adenoviruses, total coliforms, and Escherichia coli in seawater.

A two-month survey was conducted in order to evaluate the effects of rainfall on the fate of microorganisms in seawater in the Tokyo Bay, Japan. The seawater sample (1,000 mL) was applied to a method to concentrate virus, followed by a quantification of human adenoviruses using the real-time PCR. Total coliforms and E. coli, which were determined by the colony forming method, were detected in all 47 seawater samples, while human adenoviruses were detected in 38 (81%) of the samples. The concentration of tested microorganisms showed 1-2 log units increase after rainfall events, followed by the gradual decrease to the level before the rainfall within a few days.     

Debates over dam removal in Japan

Japan is facing a severe problem with the aging of its infrastructure, including dams. We studied eight controversial cases (the Ararse, Okusawa, Setoishi, Tamayodo, Minochi, Yasuoka, Tsuga and Nibutani Dam) involving dam removal in Japan and elucidated the triggers and suggested reasons for the debate. Renewal of water rights was a major trigger in three of the eight cases. Environmental reasons in five cases were not relevant to the demolition decision regarding dams conferring public benefit, even if restoration of the river environment was a recognized benefit. Compared with single‐purpose dams, the removal debate for a multi‐purpose dam, based on economic reasons regarding a single function, did not gain traction. Among the eight cases, there has been no case triggered by the renewal of water right by reason of economics, which should be highlighted options for stock management purposes.     

Seminatural Occurrence of Fullerenes

In continuation to our search of fullerenes in usual soots, sixteen additional samples of Chinese ink stick have been analyzed by HPLC. When combined with our previous results, we recognize that C₆₀-content in Chinese ink sticks decreases with time following the first order rate law. This novel observation was interpreted in terms of diffusion-dissipation of C₆₀ molecules through the solid stick.     

Compact and low-loss interleave filter employing lattice-form structure and silica-based waveguide

This paper describes a compact and practical interleave filter with uniform multi/demultiplexing properties and a wide operational wavelength range realized by using a lattice-form structure and a silica-based waveguide. In the design, we optimized the bandwidth by controlling the lattice stage number and the loss ripple in the spectrum. Moreover, we propose a novel coupler with a large fabrication tolerance, a new tandem configuration that provides uniform characteristics and low dispersion, a polarization dependence compensation method, and a folded configuration, which are effective in realizing a high-performance interleave filter. Based on the above techniques, we fabricated a 50-GHz channel spacing interleave filter by using planar-lightwave-circuit technologies and demonstrated that it performed well throughout the C-band, exhibiting a low insertion loss of about 2 dB, a low chromatic dispersion of within +/-20 ps/nm, a 1-dB passband width of over 34 GHz, and a 30-dB stopband width of over 25 GHz, which are sufficient for a 10-Gbps transmission system.     

Amplification of c-MYC oncogene and point mutation of N-RAS oncogene point mutation in acute myelocytic leukemias with double minute chromosomes

Two patients with acute myelocytic leukemia (AML) showing double minute (dmin) chromosomes were analysed to identify oncogene activation. Cytogenetic analysis showed 1-53 dmin chromosomes with the normal karyotype in the first patient and 1-84 dmin chromosomes with complex chromosome aberrations. Analysis of DNA from two patients revealed five- to tenfold amplification of c-MYC oncogene in the leukemic cells. The other sixteen oncogenes studied showed no increase in the gene content. Furthermore, a transforming gene, N-RAS was detected in the first patient by nude mouse tumorigenicity assay (in vivo selection assay). These results suggest that the amplification of c-MYC gene is common in dmin-positive AML patients and co-ordination of c-MYC and N-RAS oncogene might also play a significant role in the pathogenesis of some AML patients.