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171.
Marc Bescond Jean-Luc Autran Nicolas Cavassilas Daniela Munteanu Michel Lannoo 《Journal of Computational Electronics》2004,3(3-4):393-396
A program to numerically simulate point defects in nanowire metal-oxide-semiconductor field-effect transistors is described. The simulation scheme is based on the non-equilibrium Green’s function method self-consistently being obtained via the resolution of 3D Poisson’s equation. A tight-binding hamiltonian is used and the point defect is characterized by a macroscopic coulombic tail treated in the mode-space approach, plus a short range on-site perturbation potential energy, treated exactly. The effect on internal quantities and on the transistor characteristics is studied as a function of the strength and the location of the defect potential. Subthreshold current is found to vary in a factor 10 according to the position of the impurity.Also With Institut Universitaire De France (IUF). 相似文献
172.
This book is the result of months of work by a small group interested in ethical debates surrounding diverse professional practices. The different chapters examine the relationships among ethics, morality, and psychology. Of special interest are ethical questions relating to the conduct of research; the use and interpretation of standardized tests, given issues of validity and reliability; and the problems of developing and transmitting expertise in psychological practice. The values of respect, liberty, and justice are seen as relevant and applicable to psychological practice. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
173.
Grimandi G Soueidan A Anjrini AA Badran Z Pilet P Daculsi G Faucheux C Bouler JM Guicheux J 《Microscopy research and technique》2006,69(8):606-612
The increased generation and up-regulated activity of bone resorbing cells (osteoclasts) play a part in the impairment of bone remodeling in many bone diseases. Numerous drugs (bisphosphonates, calcitonin, selective estrogen receptor modulators) have been proposed to inhibit this increased osteoclastic activity. In this report, we describe a pit resorption assay quantified by scanning electron microscopy coupled with image analysis. Total rabbit bone cells with large numbers of osteoclasts were cultured on dentin slices. The whole surface of the dentin slice was scanned and both the number of resorption pits and the total resorbed surface area were measured. Resorption pits appeared at 48 h and increased gradually up to 96 h. Despite the observation of a strong correlation between the total resorption area and the number of pits, we suggest that area measurement is the most relevant marker for osteoclastic activity. Osteotropic factors stimulating or inhibiting osteoclastic activity were used to test the variations in resorption activity as measured with our method. This reproducible and sensitive quantitative method is a valuable tool for screening for osteoclastic inhibitors and, more generally, for investigating bone modulators. 相似文献
174.
Balamurugan A Benhayoune H Kannan S Laquerriere P Michel J Balossier G Ferreira JM 《Microscopy research and technique》2008,71(9):684-688
The present study deals with the short-term physicochemical reactions at the interface between bioactive glass particles [55SiO(2)-20CaO-9P(2)O(5)-12Na(2)O-4MgO. mol%] and biological fluid (Dulbecco Modified Eagle's Medium (DMEM)). The physicochemical reactions within the interface are characterized by scanning transmission electron microscopy (TEM) (STEM) associated with Energy-dispersive X-ray spectroscopy (EDXS). Microanalysis of diffusible ions such as sodium, potassium, or oxygen requires a special care. In the present investigation the cryo-technique was adopted as a suitable tool for the specimen preparation and characterization. Cryosectioning is essential for preserving the native distribution of ions so that meaningful information about the local concentrations can be obtained by elemental microanalysis. The bioglass particles immersed in biological fluid for 24 h revealed five reaction stages: (i) dealkalization of the surface by cationic exchange (Na(+), Ca(2+) with H(+) or H(3)O(+)); (ii) loss of soluble silica in the form of Si(OH)(4) to the solution resulting from the breakdown of Si--O--Si bonds (iii); repolymerization of Si(OH)(4) leading to condensation of SiO(2)); (iv) migration of Ca(2+) and PO(4) (3-) to the surface through the SiO(2)-rich layer to form CaO-P(2)O(5) film; (v) crystallization of the amorphous CaO-P(2)O(5) by incorporating OH-- or CO(3) (2-) anions with the formation of three different surface layers on the bioactive glass periphery. The thickness of each layer is approximately 300 nm and from the inner part to the periphery they consist of Si--OH, which permits the diffusion of Ca(2+) and PO(4) (3-) ions and the formation of the middle Ca--P layer, and finally the outer layer composed of Na--O, which acts as an ion exchange layer between Na(+) ions and H(+) or H(3)O(+) from the solution. 相似文献
175.
176.
The literature of portfolio optimization is extensive and covers several important aspects of the asset allocation problem. However, previous works consider simplified linear borrowing cost functions that leads to suboptimal allocations. This paper aims at efficiently solving the leveraged portfolio selection problem with a thorough borrowing cost representation comprising a number lenders with different rates and credit limits. We propose a two-stage stochastic programming model for asset and debt allocation considering a CVaR-based risk constraint and a convex piecewise-linear borrowing cost function. We compare our model to its counterpart with the fixed borrowing rate approximation used in literature. Numerical results show our model significantly improves performance in terms of risk-return trade-off. 相似文献
177.
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179.
Javier Solano Martínez Jérôme Mulot Fabien Harel Daniel Hissel Marie-Cécile Péra Robert I. John Michel Amiet 《Engineering Applications of Artificial Intelligence》2013,26(7):1772-1779
The aim of this paper is to present experimental validation results of an energy management system for hybrid electrical vehicles based on type-2 fuzzy logic. The energy management system (EMS) is designed by extracting knowledge from several experts using surveys. The consideration of interval type-2 fuzzy sets enables modeling the uncertainty in the answers of the experts. The validation of the EMS is performed on a real-scale heavy duty vehicle equipped with different energy sources such as batteries, fuel cell system and ultracapacitors. Experimental results are strong evidence that type-2 fuzzy logic is wide adapted for performing the energy management in hybrid electrical vehicles. 相似文献
180.