Adjunctive Application of Antimicrobial Photodynamic Therapy in Nonsurgical Periodontal Treatment: A Review of Literature

Periodontal disease is caused by dental plaque biofilms, and the removal of these biofilms from the root surface of teeth plays a central part in its treatment. The conventional treatment for periodontal disease fails to remove periodontal infection in a subset of cases, such as those with complicated root morphology. Adjunctive antimicrobial photodynamic therapy (aPDT) has been proposed as an additional treatment for this infectious disease. Many periodontal pathogenic bacteria are susceptible to low-power lasers in the presence of dyes, such as methylene blue, toluidine blue O, malachite green, and indocyanine green. aPDT uses these light-activated photosensitizer that is incorporated selectively by bacteria and absorbs a low-power laser/light with an appropriate wavelength to induce singlet oxygen and free radicals, which are toxic to bacteria. While this technique has been evaluated by many clinical studies, some systematic reviews and meta-analyses have reported controversial results about the benefits of aPDT for periodontal treatment. In the light of these previous reports, the aim of this review is to provide comprehensive information about aPDT and help extend knowledge of advanced laser therapy.     

Recoverable shear strain of liquid crystal‐forming concentrated hydroxypropyl cellulose solutions

The recoverable shear strain (S_R) for the liquid crystal‐forming hydroxypropyl cellulose solutions was determined by means of a concentric cylinder rotational apparatus as functions of shear stress prior to recovery and concentration of the solutions at 30°C. S_R greatly depended on shear stress and concentration; the phase of the solution (the single phase or biphase) governed the dependences of S_R on stress and concentration. S_R increased with increasing stress for the single phase and decreased for the biphase. S_R seemed to be related to the die swell (B): S_R ∝ Bⁿ. S_R exhibited a maximum and a minimum with respect to concentration. S_R for the cellulosic cholesteric liquid crystalline solutions was greater than that for the isotropic solutions. A model was proposed for explaining the greater S_R. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 85: 865–872, 2002     

Fracture toughness of short carbon fibre reinforced thermoplastic polyimide

The fracture toughness testing of short fibre reinforced thermoplastic materials were performed. Materials tested were the polyimide resin and also that reinforced with 20 wt% or 30 wt% short carbon fibre. For introducing the initial crack, the tapping method, the sliding method and the bridge indentation method were examined. Among them, the sliding method was found to be effective for every case. The fracture tests were conducted by the three-point bending test with several loading rates. Stable crack growth was observed for the neat material while unstable fracture occurred for the reinforced materials. The critical values of the stress intensity factor at crack initiation were greater for the reinforced materials than for the neat resin. The fracture toughness of the 30 wt% reinforced material was independent of loading rate while that of 20 wt% reinforced material increased with loading rate. In order to investigate the fracture mechanisms, fractographic observations were also performed.     

Various hybrid methods based on genetic algorithm with fuzzy logic controller

In this paper we propose several efficient hybrid methods based on genetic algorithms and fuzzy logic. The proposed hybridization methods combine a rough search technique, a fuzzy logic controller, and a local search technique. The rough search technique is used to initialize the population of the genetic algorithm (GA), its strategy is to make large jumps in the search space in order to avoid being trapped in local optima. The fuzzy logic controller is applied to dynamically regulate the fine-tuning structure of the genetic algorithm parameters (crossover ratio and mutation ratio). The local search technique is applied to find a better solution in the convergence region after the GA loop or within the GA loop. Five algorithms including one plain GA and four hybrid GAs along with some conventional heuristics are applied to three complex optimization problems. The results are analyzed and the best hybrid algorithm is recommended.     

Living cationic polymerization of a vinyl ether with a triester pendant

Summary Cationic polymerization of CH₂=CH-O-CH₂CH₂C(COOC₂H₅)₃, a vinyl ether with three pendent esters, initiated by the HI/I₂ system in toluene at –40 °C afforded living polymers with a controlled molecular weight ( = 10³–10⁴) and a narrow molecular weight distribution ( = 1.1–1.2). The number-average molecular weight of the polymers was directly proportional to monomer conversion and the monomer-to-initiator (HI) feed ratio. The polymers obtained with BF₃O(C₂H₅)₂ had a fairly high molecular weight ( 10⁵, 5 × 10⁴) and a broad molecular weight distribution. The triester vinyl ether was similar in reactivity to alkyl counterparts and one order of magnitude more reactive than the corresponding mono- and diester vinyl ethers.     

Hardware system of the Earth Simulator

The Earth Simulator (ES), developed under the Japanese government’s initiative “Earth Simulator project”, is a highly parallel vector supercomputer system. In this paper, an overview of ES, its architectural features, hardware technology and the result of performance evaluation are described.

In May 2002, the ES was acknowledged to be the most powerful computer in the world: 35.86 teraflop/s for the LINPACK HPC benchmark and 26.58 teraflop/s for an atmospheric general circulation code (AFES). Such a remarkable performance may be attributed to the following three architectural features; vector processor, shared-memory and high-bandwidth non-blocking interconnection crossbar network.

The ES consists of 640 processor nodes (PN) and an interconnection network (IN), which are housed in 320 PN cabinets and 65 IN cabinets. The ES is installed in a specially designed building, 65 m long, 50 m wide and 17 m high. In order to accomplish this advanced system, many kinds of hardware technologies have been developed, such as a high-density and high-frequency LSI, a high-frequency signal transmission, a high-density packaging, and a high-efficiency cooling and power supply system with low noise so as to reduce whole volume of the ES and total power consumption.

For highly parallel processing, a special synchronization means connecting all nodes, Global Barrier Counter (GBC), has been introduced.     

Cellular array processor CAP and applications

The general-purpose, highly parallel, cellular array processor (CAP) we developed features multiple-instruction stream, multiple-data stream (MIMD) processing and image display. Processor elements can number in several hundreds. The present system uses 256 processors. Each processor element consists of a general-purpose microprocessor, memory, and a special VLSI chip that performs parallel-processing-specific functions such as processor communication and synchronization. The VLSI has two 2M byte/s independent common bus interfaces for data broadcating and six 15M bit/s serial communication ports for local data communication. The chip also can process image data in real time for multiple processors. Use of the communication interfaces enables a variety of processor networks to be configured. One CAP application has been computer graphics, in which ray tracing is used to generate quality images.     

Multiobjective evolutionary algorithm for manufacturing scheduling problems: state-of-the-art survey

Scheduling is an important tool for a manufacturing system, where it can have a major impact on the productivity of a production process. In order to find an optimal solution to scheduling problems it gives rise to complex combinatorial optimization problems. Unfortunately, most of them fall into the class of NP-hard combinatorial problems. In this paper, we focus on the design of multiobjective evolutionary algorithms (MOEAs) to solve a variety of scheduling problems. Firstly, we introduce fitness assignment mechanism and performance measures for solving multiple objective optimization problems, and introduce evolutionary representations and hybrid evolutionary operations especially for the scheduling problems. Then we apply these EAs to the different types of scheduling problems, included job shop scheduling problem (JSP), flexible JSP, Automatic Guided Vehicle (AGV) dispatching in flexible manufacturing system (FMS), and integrated process planning and scheduling (IPPS). Through a variety of numerical experiments, we demonstrate the effectiveness of these Hybrid EAs (HEAs) in the widely applications of manufacturing scheduling problems. This paper also summarizes a classification of scheduling problems, and illustrates the design way of EAs for the different types of scheduling problems. It is useful to guide how to design an effective EA for the practical manufacturing scheduling problems. As known, these practical scheduling problems are very complex, and almost is a combination of different typical scheduling problems.     

Sex Attractant Pheromone from the Rice Stalk Stink Bug, Tibraca limbativentris Stal

The male-produced sex pheromone from the Brazilian rice stalk stink bug Tibraca limbativentris is reported. Olfactometer bioassays with sexually mature males and females showed that males attracted females, which suggests that males release a sex pheromone. Males were not attracted to either sex, nor were females attractive to conspecific females. Attraction of the females to males was highest at night. The headspace volatiles collected from male and female bugs were analyzed by gas chromatography (GC) and GC–mass spectrometry. Two male-specific compounds were identified as isomers of 1′S-zingiberenol, whereas a series of defensive compounds were identified in extracts from both sexes. Zingiberenol has three chiral centers, and the nonselective syntheses used produced two groups of isomers, zingiberenol I containing four isomers, namely (1RS,4RS,1′R)-4-(1′,5′-dimethylhex-4′-enyl)-1-methylcyclohex-2-en-1-ol, and zingiberenol II containing the other four isomers, namely (1RS,4RS,1′S)-4-(1′,5′-dimethylhex-4′-enyl)-1-methylcyclohex-2-en-1-ol. Both groups of stereoisomers were more attractive than hexane controls. The absolute configuration of the insect-produced pheromonal components remains to be elucidated, but the 1′S stereochemistry was established for at least one of the isomers.     

Simultaneous determination of ochratoxin A, B and citrinin in foods by HPLC-FL and LC/MS/MS

Methods using high-performance liquid chromatography with fluorescence detection (HPLC-FL) and using liquid chromatography with tandem mass spectrometry (LC/MS/MS) were developed for simultaneous determination of ochratoxin A (OTA), ochratoxin B (OTB) and citrinin (CIT) in cereal, fruit, and coffee products. The samples were extracted with ethyl acetate under an acidic condition, and then cleaned up with liquid-liquid separation. The test solutions were analyzed by reverse-phase HPLC-FL and LC/MS/MS. Mass spectral acquisition was performed in positive ion mode by applying multiple reaction monitoring. The performances of both detectors were almost equivalent. The recoveries of OTA and OTB were 87-111%, and that of CIT were 70-88%. The limits of quantification (S/N> or =10) of OTA, OTB and CIT was 0.1 mug/kg or less. These methods were considered to be useful for the determination of the three mycotoxins at low levels (0.1 microg/kg).