Useful solar heat gains in multi-zone non-domestic buildings as a function of orientation and thermal time constant

Two parameters affecting useful solar absorption are orientation and thermal mass. Solar energy absorption in buildings depends on these parameters in a complex manner particularly when considering large glazing ratios and large direct components of insolation. Therefore, where parameters of different zones in a multi-zone building vary, useful solar absorption will also vary. For higher northern latitudes, compared with south orientation, useful solar absorption differs by about 2%, 4% and 6% between large and small time constants for east, west and north orientations, respectively. The smallest and largest differences are for east and north orientations, respectively. Fenestration design should be a consequence of orientation and overshading, seeking to balance daylight, solar gains and heat losses.     

Neurovisceral integration in cardiac and emotional regulation

The utility of heart-rate variability (HRV) to index important aspects of neural control of the heart has made it one of the most valuable tools for researchers interested in health and behavior. However, most of the literature and extant data on the central origins of HRV have been derived from animal models. As yet little is known about the central nervous system (CNS) origins and concomitants in humans. In the following we will briefly detail a set of neural structures that have been associated with important CNS functions including cardiac regulation and emotional regulation. We will briefly summarize recent data using pharmacological, neuroimaging, and psychophysiological techniques that have examined CNS concomitants of HRV especially during emotion. Based on these and other data will we report the results of a computational model that examined the interactions of several neural structures and their effect on emotion-related HRV.     

Modeling electric field transfer of excitation at cell junctions

The electric field (EF) model was first developed on a "breadboard" using physical electric components (e.g., resistors, capacitors, batteries) and was then modeled mathematically by a series of differential equations and matrix equations and simulated on a large computer (CDC-6400). The results obtained by the two methods agreed very closely. However, these two methods of analysis are quite cumbersome. Therefore, in order to simplify the EF simulation, we wanted to model it on the PSpice program. In this article we discuss how we succeeded in demonstrating transmission of excitation from cell to cell in cardiac muscle and smooth muscle based on EF transmission at the cell junctions.     

Temperature control of buildings by adobe wall design

The adobe house developed in the hot arid climate of the American Southwest has the virtue of being cool in the day and warm in the night. The adobe wall acts as a filter giving nearly a 12-hr phase lag in the outside temperature oscillation. However, on reaching the inside, the oscillation suffers a strong attenuation in amplitude. In a previous paper it was shown that if the resistivity of the wall could be varied in a certain way from outside to inside, thenthe attenuation would be considerably reduced. In this paper a formula is given for the minimum possible attenuation under given design restrictions. Then it is shown how to make an optimum wall by suitably proportioning two or three layers of different materials. Numerical illustrations are given.     

The MITRE E3 family of models structure and results

A family of energy/economic/environmental (E³) models is presented as a mechanism for analysing national policy issues. The family consists of discrete models which are designed to be run in an integrated manner. The outputs of certain models provide the inputs to the next. This structure allows the analyst to readily incorporate an understanding of regional factors such as local energy prices, concerns over air quality, water availability, or attitudes towards construction of new energy facilities, into national assessments of energy policies. This paper reviews the analytic framework within which energy policy issues are currently addressed. The initial family of E³ models is described with the emphasis on the data linkages and feedback which are provided when these models are run sequentially. The ongoing MITRE research programme with the E³ family of models is presented and plans and opportunities for future work are outlined.     

On the mechanisms of adenosine induced pulmonary vasoconstriction in rats

The effect of adenosine on pulmonary vessels was studied in isolated perfused rat lungs. Drugs were administered intra-arterially in a fixed volume of 0.1 ml Krebs solution as bolus injections. Adenosine responses were obtained before and 10 min after drug injections. When applied in logarithmically increasing doses (1-100 micrograms/ml), adenosine caused dose-dependent increases in pulmonary perfusion pressure (e.g. pulmonary vasoconstriction) which were readily reversible. Challenging adenosine with quinidine, dihydroergocristine and cyproheptadine (2 micrograms/ml each) did not significantly alter adenosine responses. Pretreatment of lungs with 0.5 mM theophylline, 10 micrograms/ml indomethacin, 30 micrograms/ml tebokan (a PAF antagonist) or 1 microgram/ml methylene blue for 10 min, however, antagonized the vasoconstrictor effect of the drug significantly. From these experiments, it was concluded that the mechanisms underlying the pulmonary vasoconstrictor action of adenosine are complex, and that both types of purinoceptors, prostaglandins, PAF and other vascular endothelial hormones might be involved.