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41.
Domestic energy use accounts for more than a quarter of CO2 emissions in the UK. Traditional approaches to energy reduction look at direct emissions savings, and recommend insulation and efficiency as more cost-effective than microgeneration. However, microgeneration has indirect, ‘soft’ benefits and could play a significant role in emissions reduction. Current uptake of microgeneration in the UK is low, with various barriers—economic, technical, cultural, behavioural and institutional—both to uptake and to maximising energy and emissions savings once installed. Subsidies and spreading information alone do not guarantee maximising uptake, and even if successful, this is not enough to maximise savings. The industry focuses on maximising sales, with no incentives to ensure best installations and use; householders do not have access to the best information, and user behaviour does not maximise energy and emission savings. This is related to a broader state of socio-technical ‘lock-in’ in domestic energy use; there’s a lack of connection between personal behaviour and energy consumption, let alone global climate change. This suggests that a major cultural–behavioural shift is needed to reduce energy/emissions in the home. Transition theory and strategic niche management provide insights into possible systemic change and a suitable framework for future policies, such as supporting a variety of radically innovative niches, both technological and social. Microgeneration, properly employed, has the potential to play a part in such a transition by increasing awareness and energy literacy and empowering people to seriously engage in energy debates as producers, as well as consumers, of energy. This deeper understanding and heightened responsibility are crucial in a shift toward bottom-up emission-reducing behaviour change and better acceptance of top-down energy-saving policy measures, as part of a new domestic energy paradigm. The implications for policy are that, as well as supporting the technologies, it needs to support existing niches and to develop new niche experiments. Policy needs to consider how to promote empowerment and responsibility and support or even develop new energy sector models; this will involve a range of stakeholders and multiple governance levels, not just national incentive schemes.  相似文献   
42.
In this letter we propose a novel distributed technique for dynamic spectrum management of DSL lines. The proposed method generalizes several known techniques, by imposing pricing for use of spectrum. We propose a simple mechanism that allows each line to choose an appropriate pricing function independently of the other lines. Finally, by incorporating a total power constraint, the algorithm is capable of self-correcting an overly ambitious pricing function. We also provide simulated examples based on measured DSL lines.  相似文献   
43.
44.
It has been 100 years since the discovery of renin by Tigerstedt and Bergman. Since that time, numerous discoveries have advanced our understanding of the renin-angiotensin system, including the observation that angiotensin II is the effector molecule of this system. A remarkable aspect of angiotensin II is the many different physiological responses this simple peptide induces in different cell types. Here, we focus on the signal transduction pathways that are activated as a consequence of angiotensin II binding to the AT1 receptor. Classical signaling pathways such as the activation of heterotrimeric G proteins by the AT1 receptor are discussed. In addition, recent work examining the role of tyrosine phosphorylation in angiotensin II-mediated signal transduction is also examined. Understanding how these distinct signaling pathways transduce signals from the cell surface will advance our understanding of how such a simple molecule elicits such a wide variety of specific cellular responses.  相似文献   
45.
When stimulated through their antigen receptor without requisite costimulation, T cells enter a state of antigen-specific unresponsiveness termed anergy. In this study, signaling through the common gamma chain of the interleukin-2 (IL-2), IL-4, and IL-7 receptors in the presence of antigen was found to be sufficient to prevent the induction of anergy. After culture with IL-2, IL-4, or IL-7, Jak3 kinase was tyrosine-phosphorylated, which correlated with the prevention of anergy. Therefore, a signal through the common gamma chain may regulate the decision of T cells to either clonally expand or enter a state of anergy.  相似文献   
46.
Presents data from animal studies to refute D. O. Hebb's (1978) claim of irreversibility of learning and problem-solving skill deficits in environmentally restricted rats. When exposure to the enriched environment is extended beyond the amount of time spent in early deprivation, the effects of early restriction appear to be reversible. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
47.
48.
5 groups of 15 female undergraduates reporting fear of snakes participated in 2 behavioral avoidance tests employing a snake as the target object. 4 groups were first tested under low demand for approach and then under the same conditions or under 1 of 3 conditions of demand increase, mediated by instructions, mode of administration, or both. The 5th group was tested under high, then low demand. Ss first tested under low demand showed significantly more fear than those first tested under high demand. In addition, Ss in the demand-increase groups showed significant increases in approach at the 2nd behavior avoidance test, while Ss in the demand-decrease group showed a significant reduction in approach. Ss in the repeated-measure control group showed no significant changes. (16 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
49.
Two high strength P/M nickel-base superalloys, AF-115 and AF2-1DA, with different defect populations, were tested to determine the effect of preexisting defects on the fatigue crack initiation process. Strain controlled continuous cycle fatigue tests were performed at room and at elevated temperature; these were followed by fractographic examination to characterize both the location and character of the fatigue origins. In most cases, particularly at elevated temperature, the initiation process was associated with a large pre-existing defect, either a pore or a nonmetallic inclusion. There was also a change in the location of the crack that caused failure as the strain range varied: at high strain ranges initiation occurred at or near the specimen’s surface, while at the lower strain ranges the failure originated in the specimen’s interior. The initiation mode for both alloys at room temperature was different than at elevated temperature. At room temperature, Stage I crystallographic cracking at or near the surface dominated the process in all strain range regimes. This difference was attributed, in part, to the differences in deformation mode for nickel-base superalloys at room and elevated temperature. Formerly with Metals and Ceramics Division, Air Force Materials Laboratory, Wright-Patterson AFB, OH.  相似文献   
50.
Semijoin is a relational operator used in many relational query processing algorithms. Semijoins can be used to “reduce” the database by delimitting portions of the database that contain data relevant to a given query. For some queries, there exist sequences of semijoins that delimit the exact portions of the database needed to answer the query. Such sequences are called full reducers.

This paper considers a class of queries called natural inequality queries (NI queries), and characterizes a subclass for which full reducers exist. We also present an efficient algorithm that decides whether an NI query lies within this subclass, and constructs a full reducer for the query. The NI queries are a subset of the aggregate-free, conjunctive queries of QUEL, and permit join clauses to include <, , =, , >.  相似文献   

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