Effect of platelet-activating factor on lipoprotein lipase and blood lipids

We investigated the effect of platelet-activating factor (PAF) and of the PAF specific antagonist CV-6209 on plasma lipid metabolism, and particularly on post-heparin plasma lipolytic activity in male Wistar rats. Lipoprotein lipase (LPL) activity was enhanced by intravenous injection of PAF before intravenous injection of heparin when the PAF dose was low (0.2 μg/kg). PAF activated hepatic triacylglycerol lipase (HTGL) activity dose-dependently. Plasma triacylglycerols (TG) significantly decreased with the activation of LPL and/or HTGL. Plasma total cholesterol (TC) and phospholipid (PL) levels decreased at a low dose of PAF (0.2 μg/kg), but increased when higher doses were used. The PAF antagonist CV-6209 partially reversed the PAF induced effects on HTGL, TC and PL. Based on a paper presented at the Third International Conference on Platelet-Activating Factor and Structurally Related Alkyl Ether Lipids, Tokyo, Japan, May 1989.     

One-step formation of ethyl methyl ketone from 1-butene and water on ultrastable Y-type zeolite catalyst

Proton exchanged ultrastable Y-type zeolite with silica/alumina = 40 showed a pronounced catalytic activity for the formation of ethyl methyl ketone directly from 1-butene and water. The formation rate of ethyl methyl ketone was much higher than those on MoO₃-based catalysts in the oxidation of 1-butene by oxygen. It was suggested that the basic site necessary for the formation of ethyl ketone directly from 1-butene and water would be the pentacoordinated Al.     

Thraustochytrid as a potential source of carotenoids

Thraustochytrids, marine protists whose dominant genera are Thraustochytrium and Schizochytrium, belong to the kingdom Chromista and are known as an industrial source of DHA. We describe here that thraustochytrid strain KH105, isolated as a DHA producer, also accumulates significant levels of β-carotene and xanthophylls including canthaxanthin and astaxanthin. A4-d cultivation using a medium composed of 10% glucose and less than 0.3% of nitrogen sources in a half-concentration of seawater gave an astaxanthin production up to 6.1 mg/L, and canthaxanthin content reached more than 10 mg/L under conditions where a higher concentration of nitrogen sources (6%) was employed. It might be advantageous in mass production systems for these carotenoids to be extracted readily by simply suspending the cells with organic solvents such as acetone and chloroform. Analyses on the morphological and life history features of the KH105 strain revealed that it belongs to the genus Schizochytrium. This particular species of thraustochytrids is thus considered to be a promising source of xanthophylls as well as DHA for use in the food industry.     

Electron-beam irradiation-induced grafting of acrylonitrile onto polyethylene

Low- and high-density polyethylene (PE) films were grafted with acrylonitrile (AN) by electron beam prior to irradiation. The distribution of graft chains over the cross section of the sample film was analyzed in terms of the distribution of nitrogen atoms contained in the AN by means of an electron probe microanalyzer (EPMA), and graft sites were studied in relation to the effect of grafting temperature on the percent graft and the oxygen permeability of the sample films. It was found that diffusion of AN into the film was the rate-limiting step in the grafting process, thus restricting the grafting to the surface of the film in the initial grafting stages. However, the grafting shifted to the center of film as the graft process proceeded, until a uniform distribution of graft chains was observed across the entire film thickness. High-density polyethylene (HDPE) was found to display a higher percent graft than did low-density polyethylene (LDPE), and percent graft tended to increase with increasing grafting temperature. On the other hand, film oxygen permeability decreased with increasing percent graft, but this decreasing trend decreased with increasing percent graft. These findings suggest that the grafting is initiated by radicals trapped in the amorphous phase near the crystalline regions and at the surface of crystallites and that graft chains grow toward the amorphous regions. As for the radicals contributing to graft polymerization, it appears that AN permeates deeper near the crystalline surface and that graft chains grow from these sites.     

Adaptive interpolation scheme for NURBS curves with the integration of machining dynamics

This paper develops a comprehensive interpolation scheme for non-uniform rational B-spline (NURBS) curves, which does not only simultaneously meet the requirements of both constant feedrate and chord accuracy, but also real-time integrates machining dynamics in the interpolation stage. Although the existing work in this regard has realized the importance to simultaneously consider chord error and machining dynamics, none has really incorporated these in one complete interpolation scheme. In this paper, machining dynamics is considered for three aspects: sharp corners or feedrate sensitive corners on the curves, components with high frequencies or frequencies matching machine natural ones and high jerks. A look-ahead module was developed for detecting and adaptively adjusting the feedrate at the sharp corners. By Fast Fourier Transform (FFT) analysis with a moving window in the interpolation stage identified were some special frequency components such as those containing high frequencies or with frequencies matching machine natural ones. Then, the notch filtering or time spacing method was used to eliminate these components. To more completely reduce feedrate and acceleration fluctuations, the jerk-limited algorithm was also developed. Finally, the interpolated feedrate was further smoothened with B-spline fitting method and the NURBS curves were re-interpolated with the smoothened feedrate. During the interpolation, the chord error was repeatedly checked and confined in the prescribed tolerance. Two NURBS curves were used as examples to test the feasibility of the developed interpolation scheme.     

Improvement of Formability by Oscillation of Internal Pressure in Pulsating Hydroforming of Tube

A new history of internal pressure in the hydroforming processes of tubes is developed to attain high formability. The effect of improvement of formability by the oscillation of internal pressure in a pulsating hydroforming process of tubes is examined using both finite element simulation and experiment. The deformation behaviour during the hydroforming is greatly affected by the oscillation of internal pressure. For a monotonic history of small internal pressure, the wrinkling was caused by insufficient bulging, whereas the necking and bursting occurred for a monotonic history of large internal pressure. The occurrence of these defects can be avoided by oscillating the internal pressure in the pulsating hydroforming. The improvement of formability in the pulsating hydroforming is due to both low pressure and oscillation of pressure. The effects of the amplitude and cycle number of pressure in the pulsating hydroforming on the deformation behaviour are investigated. It is found the oscillation of internal pressure is effective in preventing the occurrence of defects.     

Repeatedly foldable AMOLED display

In this study, a 5.9‐inch foldable active‐matrix organic light emitting diode (AMOLED) display was developed. A folding test was performed repeatedly. The display survived the folding test (100,000 folds) with a curvature radius of 2 mm. To protect an organic light emitting diode (OLED) against moisture, inorganic passivation layers are provided on the upper and lower sides of the flexible display. Using our transfer technology, high density passivation layers can be obtained. The measured water vapor transmission rate of the layer is 7 × 10^?6 g/m²?day or less, which improves OLED reliability. With these techniques, we have developed a book‐type display, which is repeatedly foldable like a book, and a tri‐fold display including a display area, which is foldable in three.     

Data Center as a Key Player of a District Electric Power and Heat Network System： A Comparison in Urban and Suburb Regions

A DC （data center） demands air-conditioning power as large as the 1/3-1/2 of total electricity consumption. Thus, energy saving of cooling power of DC yields considerable effect on both economic and environmental views. PV （Photovoltaic） and absorption refrigerator with CGS （cogeneration systems） or gas boiler are possible power saving options. The waste warm air from DC would be utilized for greenhouse heating when DC and greenhouse locate near in the suburbs. In this study, the authors develop an energy network model to assess the potential contribution of DC as a major electric power and chilled air consumer as well as the warm air supplier in a district to the energy efficiency improvement. The evaporation heat of LNG （liquefied natural gas） utilization is also considered as well as PV, CGS. This model is applied to the cases of the urban area in Tokyo which involves athletic center, shops and hospital and the suburbs including greenhouse and then compared.     

Mean–variance relationship of the number of flows in traffic aggregation and its application to traffic management

We consider the mean–variance relationship of the number of flows in traffic aggregation, where flows are divided into several groups randomly, based on a predefined flow aggregation index, such as source IP address. We first derive a quadratic relationship between the mean and the variance of the number of flows belonging to a randomly chosen traffic aggregation group. Note here that the result is applicable to sampled flows obtained through packet sampling. We then show that our analytically derived mean–variance relationship fits well those in actual packet trace data sets. Next, we present two applications of the mean–variance relationship to traffic management. One is an application to detecting network anomalies through monitoring a time series of traffic. Using the mean–variance relationship, we determine the traffic aggregation level in traffic monitoring so that it meets two predefined requirements on false positive and false negative ratios simultaneously. The other is an application to load balancing among network equipments that require per-flow management. We utilize the mean–variance relationship for estimating the processing capability required in each network equipment.     

Autonomic load balancing of flow monitors

In monitoring flows at routers for flow analysis or deep packet inspection, the monitor calculates hash values from the flow ID of each packet arriving at the input port of the router. Therefore, the monitors must update the flow table at the transmission line rate, so high-speed and high-cost memory, such as SRAM, is used for the flow table. This requires the monitors to limit the monitoring target to just some of the flows. However, if the monitors randomly select the monitoring targets, multiple routers on the route will sometimes monitor the same flow, or no monitors will monitor a flow. To maximize the number of monitored flows in the entire network, the monitors must select the monitoring targets while maintaining a balanced load among them. We propose an autonomous load-balancing method where monitors exchange information on monitor load only with adjacent monitors. Numerical evaluations using the actual traffic matrix of Internet2 show that the proposed method improves the total monitored flow count by about 50% compared with that of independent sampling. Moreover, we evaluate the load-balancing effect on 36 backbone networks of commercial ISPs.