生物可吸收材料PDLLA的聚合条件研究

通过乳酸脱水合成出高纯度的D ,L 丙交酯。以辛酸亚锡为引发剂 ,进行丙交酯开环聚合为聚乳酸 (PDLLA)的实验研究。讨论了D ,L 丙交酯开环聚合的影响因素和PDLLA聚合条件     

生物可吸收储存式药物控释载体制备研究

针对骨科疾病治疗中传统的用药方式存在的问题,研究制备了一种生物可吸收靶向式药物控释载体。首先在体外模拟天然骨的生物矿化过程,利用材料的自组装机制合成了羟基磷灰石／胶原类骨仿生复合材料,再采用热致分相／非溶剂抽提成孔技术进一步与聚乳酸复合制备了三维多孔储存式药物控释载体。通过对材料的表征和模型化合物控释实验,结果显示羟基磷灰石／胶原复合材料与天然骨类似,羟基磷灰石／胶原／聚乳酸储存式载体能达到控制释放的目的。     

Cable Modem应用系统

Internet在全世界正以超乎人们想象的速度快速增长,随着应用的多样化,人们对接入方式和接入带宽的需求也日益增加。传统电信网络在这些方面所能提供的服务已远远落后于人们的需求,而有线电视网络以其覆盖范围广、技术起点高、使用费用低、带宽资源丰富并与Internet上/下行速率相符合、无需拨号总是在线等特点越来越受到人们的青睐。随着HFC网络双向化改造的加快和计算机普及率的提高,通过有线电视网络享受网上冲浪的乐趣将成为越来越多人的生活现实。     

Preparation and Charactcrization of a Novel PDLLA/Chondroitin Sulfate/Chitosan Asymmetry Film

A novel bioactive and bioresorbable asymmetry film was prepared,The PDLLA membrane was activated by 1,6-hexanediamine to obtain a stable positive charge surface.Chondroitin sulfate and chitosan were then deposited on activated PDLLA membrane via layer-by-layer(LBL)electro-static assembly (ESA)technique.The deposition process was monitored by UV-Vis absorbance spectroscopy.The composite membrane was frozen lyophilized to form the asymmetry film and characterized by attenuated total reflectic (ATR)-FT-IR,XPS and SEM.The experimental results show that a stable 1,6-hexanediamme layer on PDLLA substrate based on the aminolysis of the polyester and the layer thickness increase linearly first with the increase of the deposited layers,and then increases slowly due to the layer interpenetration.The test results of ATR-FT- IR and SEM show the asymmetry film is modified uniformly with a dense inner layer and a porous sponge outer layer.     

基于MATLAB的骨支架转变成骨组织的仿真

把计算机技术运用于骨移植材料转变为骨组织的复杂行为研究中,采用元胞自动机方法建立仿真的计算模型,以MATLAB为开发工具,实现了模型的并行仿真并再现了仿真的动态过程,为计算机辅助骨组织工程提供了新的研究方法和工具.     

溶胶-凝胶法制备酶固定膜的工艺方法研究

研究了采用溶胶－凝胶法制备用于胆固醇生物传感器中固定酶的新型薄膜的工艺和过程，经SEM进行薄膜的表面形貌分析和酶固定及酶膜活力测试实验，发现用此薄膜固定的胆固醇氧化酶具有很高的催化活力和较好的稳定性。     

水热条件下针状羟基磷灰石单晶体的均相合成

用水热法制备出结晶度高、纯净均一的针状羟基磷灰石单晶体。从X-射线衍射谱、红外吸收光谱、透射电镜分析等方面确认了所得晶体为羟基磷灰石单晶体。根据透射电子衍射谱测量计算出的晶面间距d值与羟基磷灰石卡片的d值非常接近,由标定的晶面指数计算出的晶面夹角与实际测量值有很好的吻合,从而确定所得晶体为单晶。     

纳米氧化钛的凝胶网格制备及光催化性能研究

以氨水、三氯化钛为原料,明胶为反应介质,采用凝胶网格沉淀法制备锐钛矿型二氧化钛纳米粒子,并用XRD、SEM对产品进行了表征,探讨了部分反应条件对产品粒径的影响。实验确定最佳制备条件为:明胶含量为14%、Ti3+浓度为0.6 mol/L、NH3.H2O浓度为0.8 mol/L,所得产物粒度均匀、大小可控、不易团聚。采用光催化降解实验讨论了催化剂用量、光源、脱色时间等因素对直接耐晒翠蓝染料降解率的影响。TiO2投加量为8 g/L、高压汞灯光照1 h时,直接耐晒翠蓝脱色率可达84.17%。     

丙交酯单体的回收和表征

为减少在提纯粗丙交酯时的大量耗损,采用不同方法对粗丙交酯在重结晶过程中产生的乙酸乙酯母液进行回收,并比较了各种方法的回收率。最后用紫外光谱和红外光谱对回收的丙交酯进行表征,测试结果表明产物为环状丙交酯结构,采用辛酸亚锡作催化剂是一种高产率的回收方法。     

Osteogenesis process of tricalcium phosphate ceramics in vivo

To investigate the osteogenesis of calcium phosphate ceramics,β-TCP ceramics were implanted into the condyle femur of rabbits.and tetracycline was injected termly.Specimens were host at 1,2,3,4,5,6months after implanted.The new bone formation and osteogenesis process were observed by the histomorphology,fluorescent microscope.SEM and EPMA.The results demonstrate that,osteogenesis is active,there are abundant osteoblasts. on the surface of osteoid,mesenchymal cell hyperplasia and incursion is found in materials after 1 month,After 2 months ,there is blood vessel formation and macrophage soakage within materials.Bone-island appears and connects by bone-bridge after 3 months.β-TCP ceramics degrade and are dispersed by new formation bone.Woven bone turns into bone lamella by rebuilding and calcification.The materials entirely change their original shape and combines with bone tissue as a whole after 6 months.The typical structure of spongy bone forms.It is confirmed that β-TCP is a degradable biocompatible artificial bone material which can incorporating in life.