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991.
The standard enzymatic assay for quantification of D-sorbitol in plasma was adapted to the automatic analyzer Cobas Mira S. In the assay, NAD (reagent) in the presence of sorbitoldehydrogenase (SDH; start reagent) converts D-sorbitol to fructose with formation of NADH, which was detected automatically as the difference between the first and last readings at 340 nm. The sample blank values for each specimen were subtracted to exclude both endogenous D-sorbitol and sugars, which also react as substrates for SDH. The method is simple, rapid (40 samples/h), precise down to endogenous concentrations (coefficient of variation < 5%; limit of determination: 0.38 mg/L) and linear up to 100 mg/L. Samples with higher D-sorbitol concentrations were estimated after dilution. The method was used to measure disposition curves of sorbitol in volunteers after a single intravenous dose of 0.8 g sorbitol. 相似文献
992.
Arafa M. Fay P. Ismail K. Chu J.O. Meyerson B.S. Adesida I. 《Electron Device Letters, IEEE》1996,17(3):124-126
We report on the fabrication and characterization of high-speed p-type modulation-doped field-effect transistors (MODFETs) with 0.7-μm and 1-μm gate-lengths having unity current-gain cut-off frequencies (fT) of 9.5 GHz and 5.3 GHz, respectively. The devices were fabricated on a high hole mobility SiGe heterostructure grown by ultra-high-vacuum chemical vapor deposition (UHV-CVD). The dc maximum extrinsic transconductance (gm) is 105 mS/mm (205 mS/mm) at room temperature (77 K) for the 0.7-μm gate length devices. The fabricated devices show good pinch-off characteristics and have a very low gate leakage current of a few μA/mm at room temperature and a few nA/mm at 77 K 相似文献
993.
AC Duhaime C Christian R Armonda J Hunter R Hertle 《Canadian Metallurgical Quarterly》1996,25(3):116-122
Serum glucose and plasma C-peptide response to i.v. glucagon administration was evaluated in 24 healthy dogs, 12 dogs with untreated diabetes mellitus, 30 dogs with insulin-treated diabetes mellitus, and 8 dogs with naturally acquired hyperadrenocorticism. Serum insulin response also was evaluated in all dogs, except 20 insulin-treated diabetic dogs. Blood samples for serum glucose, serum insulin, and plasma C-peptide determinations were collected immediately before and 5, 10, 20, 30, and (for healthy dogs) 60 minutes after i.v. administration of 1 mg glucagon per dog. In healthy dogs, the patterns of glucagon-stimulated changes in plasma C-peptide and serum insulin concentrations were identical, with single peaks in plasma C-peptide and serum insulin concentrations observed approximately 15 minutes after i.v. glucagon administration. Mean plasma C-peptide and serum insulin concentrations in untreated diabetic dogs, and mean plasma C-peptide concentration in insulin-treated diabetic dogs did not increase significantly after i.v. glucagon administration. The validity of serum insulin concentration results was questionable in 10 insulin-treated diabetic dogs, possibly because of anti-insulin antibody interference with the insulin radioimmunoassay. Plasma C-peptide and serum insulin concentrations were significantly increased (P < .001) at all blood sampling times after glucagon administration in dogs with hyperadrenocorticism, compared with healthy dogs, and untreated and insulin-treated diabetic dogs. Five-minute C-peptide increment, C-peptide peak response, total C-peptide secretion, and, for untreated diabetic dogs, insulin peak response and total insulin secretion were significantly lower (P < .00l) in diabetic dogs, compared with healthy dogs, whereas these same parameters were significantly increased (P < .01) in dogs with hyperadrenocorticism, compared with healthy dogs, and untreated and insulin-treated diabetic dogs. Although not statistically significant, there was a trend for higher plasma C-peptide concentrations in untreated diabetic dogs compared with insulin-treated diabetic dogs during the glucagon stimulation test. Baseline C-peptide concentrations also were significantly higher (P < .05) in diabetic dogs treated with insulin for less than 6 months, compared with diabetic dogs treated for longer than 1 year. Finally, 7 of 42 diabetic dogs had baseline plasma C-peptide concentrations greater than 2 SD (ie, > 0.29 pmol/mL) above the normal mean plasma C-peptide concentration; values that were significantly higher, compared with the results in healthy dogs (P < .001) and with the other 35 diabetic dogs (P < .001). In summary, measurement of plasma C-peptide concentration during glucagon stimulation testing allowed differentiation among healthy dogs, dogs with impaired beta-cell function (ie, diabetes mellitus), and dogs with increased beta-cell responsiveness to glucagon (ie, insulin resistance). Plasma C-peptide concentrations during glucagon stimulation testing were variable in diabetic dogs and may represent dogs with type-1 and type-2 diabetes or, more likely, differences in severity of beta-cell loss in dogs with type-1 diabetes. 相似文献
994.
The sub-rating channel assignment strategy for PCS hand-offs 总被引:2,自引:0,他引:2
Yi-Bing Lin Noerpel A.R. Harasty D.J. 《Vehicular Technology, IEEE Transactions on》1996,45(1):122-130
A new personal communications services (PCS) hand-off scheme is proposed. This scheme provides for hand-off to radio ports on which there is no free channel by “sub-rating” an existing connection. With sub-rating, an occupied full-rate channel is temporarily divided into two half-rate channels: one to serve the existing call and the other to serve the hand-off request. The blocking probabilities (combined forced terminations of existing calls and blocking of new call attempts) of this new scheme compare favorably with the standard scheme (nonprioritizing) and the previously proposed prioritizing schemes. The costs for this scheme are presented and discussed, as well as the additional procedural complexity of implementing on-the-fly sub-rating and the impact of continuing the conversation on a lower rate channel (which may lower speech quality of increase battery drain). Analytical models and simulations investigating the traffic impacts are presented, as are the results that show that even in the highest offered load considered a 3-min conversation in the busy hour experiences less than half a second of sub-rated conversation on average and only about 3% of the calls experience more than 5.12 s of sub-rated conversation. This scheme can increase capacity by 8-35% for systems with 1% call incompletion probability 相似文献
995.
996.
997.
When designing an in-line metal detector, a three coil axially symmetric design is often employed. For maximum sensitivity to small particles, the spacing of the coils is an important factor. A formula is derived which predicts the signal produced by a metal sphere when moved along the axis of such a detector and from this a graph is produced to determine the optimum coil spacing.<> 相似文献
998.
A. Mandrino R. Eloy B. Moyen J. L. Lerat D. Treheux 《Journal of materials science. Materials in medicine》1992,3(6):457-463
Base alumina ceramics with dispersoids (BAC) are a new class of ceramics with improved mechanical properties as compared to pure alumina. They are obtained by dispersion of powder within an alumina matrix. Of the three new ceramics studied here, A20Z possesses the best mechanical properties as well as tribological properties superior to those of pure alumina whether it is used in ceramic-ceramic or ceramic-polyethylene combination.Mechanical behaviour and tissue response afterin vivo implantation were studied. Small four-point flexion bars obtained by pressureless sintering were implanted subcutaneously in the rat. The mechanical properties were unmodified even after one year from implantation.The tissue response was studied up to one year on cylinders implanted in the paravertebral muscles of Wistar rats, and was evaluated by qualitative examination of the encapsulating membrane and measurement of its thickness in relation to pure alumina. The tissue responses were comparable for both alumina and the three tested ceramics. 相似文献
999.
H. Hou J. C. Holste
B. E. Gammon
K. N. Marsh 《International Journal of Refrigeration》1992,15(6):365-371This paper reports densities of compressed R134a (1,1,1,2-tetrafluoroethane) determined by using a contiuously weighed pycnometer at 20 K intervals between 180 and 380 K at pressures from slightly greater than the vapour pressure to 70 MPa. The results are accurate to within ±0.1%. Saturated liquid densities derived by extrapolation from the experimental values agree with other reported values to within ±0.3%. 相似文献
1000.
An experimental study of the planar-flow melt-spinning process was performed in order to gain a better understanding of the
steady-state production of microcrystalline and amorphous ribbons. The dependence of the thickness of the ribbon product,T, on process parameters (wheel speed,U, nozzle/wheel gap,G, overpressure, ΔP, nozzle-slot breadth,R, and nozzle-slot width,W) was determined using an apparatus designed to deliver reproducible results. Thicknesses were reproducible to within 5%–8%.
Guided by dimensional analysis, the non-dimensional thickness (T/G) was found to depend, within the experimental error, only on a non-dimensional pressure drop (ΔP/ρU
2) and slot breadth (R/G) for fixed thermal conditions. Data from the literature and our data, which considerably extend the range, correlate consistently
on this basis. In contrast to the steady behaviour, the limits within which a uniform ribbon can be formed depend on a larger
set of parameters; this dependence is sketched with the available data. Finally, a variety of observed ribbon surface textures
(free meniscus side) is catalogued. 相似文献