The behaviour of masonry walls subjected to fire: Modelling and parametrical studies in the case of hollow burnt-clay bricks

A thermo-mechanical model is adopted in order to investigate the fire behaviour of clay masonry walls. In this analysis, conductive, convective and radiative thermal transfers are considered together with local energy consumption due to phase changes. These latter are essentially initiated by both the vaporisation of adsorbed water and the chemical transformation of clay under rising temperatures. Therefore, experimental tests at both the material scale and the brick scale are performed in order to identify the parameters that characterise the thermo-hygral behaviour of clay. For this purpose, numerical simulations are carried out on the experimentally tested hollow bricks in order to determine by back analysis these material parameters. The thermal model being validated, the thermo-mechanical behaviour of a masonry wall subjected to fire, is thereafter investigated by adopting a full three-dimensional finite-element analysis. Numerical simulations results are compared to the experimentally measured ones in terms of both temperature and out-of plane displacement fields. In this analysis, it is shown that a non-linear elastic behaviour for bricks and mortar with temperature-dependent mechanical parameters is sufficient to retrieve the overall behaviour of thin masonry walls. Finally, a parametric study provides the influence of each material parameter on the fire behaviour of the partition walls.     

Sur un modèle précis de la permittivité effective statique de la ligne microruban suspendue uniforme applicable à la technique des LECF

An accurate modelling of static effective permittivity ?_eff of a uniform suspended microstrip line is presented. This modelling is built on the variational method of moments (Vm). But this method requires high times computing for line of arbitrary shape, the width w of the uniforme line is reduced by the thickness h₁ of the air gap. The stratified microstrip patch antennas with an air gap, of arbitrary shape present this type of situation in the analysis with the method of the Finished Coupled Elementary Lines (F.c.e.l). A formal model proposed in this work, is free of integration and derivation, and is connecting the physical parameters (such as the relative permittivities ?_ri of the mediums i = 1,2…) with those of the geometrical structure (u = w/h₁ and m — h₂/h₁ where h₂ is the thickness of dielectric). The new model is valid for the full 1 ≤ ?_r ≤20, 0.5 ≤m≤ 1.5, 10^?2 ≤ult; +∞ ranges. The model is successfully compared with mesured data. This work give an accurate evaluation of ?_eff then the frequency dependence of the effective permittivity can be easily determined.     

Investigation de la gestion de qualité de service dans le réseau UMTS

Bit rate announced for the future standards of telecommunication, as well as the level of integration reached are, as many factors, determining for the establishment of new applications in mobile terminals. Nowadays, mobile video streaming services are possible. Mobile users expect to receive multimedia traffic with some performance guarantees, so we must ensure the necessary quality of service during the video transmission. This paper aims at investigating quality of service issue inUmts network. More specifically, we explore the main challenge of quality of service management to dynamically optimize the distribution of load inUmts networks. Our investigation is organized in the following way. We formalize the optimization problem which is based on the graph theory and modellingUmts network as well as mobile users and applications to be used. The simulation of our optimization model show a clear improvement of the quality of service perceived by anUmts user in terms of bit rate, blocking and connection drop.     

Ganciclovir and Its Hemocompatible More Lipophilic Derivative Can Enhance the Apoptotic Effects of Methotrexate by Inhibiting Breast Cancer Resistance Protein (BCRP)

Efflux transporters, namely ATP-binding cassette (ABC), are one of the primary reasons for cancer chemoresistance and the clinical failure of chemotherapy. Ganciclovir (GCV) is an antiviral agent used in herpes simplex virus thymidine kinase (HSV-TK) gene therapy. In this therapy, HSV-TK gene is delivered together with GCV into cancer cells to activate the phosphorylation process of GCV to active GCV-triphosphate, a DNA polymerase inhibitor. However, GCV interacts with efflux transporters that are responsible for the resistance of HSV-TK/GCV therapy. In the present study, it was explored whether GCV and its more lipophilic derivative (1) could inhibit effluxing of another chemotherapeutic, methotrexate (MTX), out of the human breast cancer cells. Firstly, it was found that the combination of GCV and MTX was more hemocompatible than the corresponding combination with compound 1. Secondly, both GCV and compound 1 enhanced the cellular accumulation of MTX in MCF-7 cells, the MTX exposure being 13–21 times greater compared to the MTX uptake alone. Subsequently, this also reduced the number of viable cells (41–56%) and increased the number of late apoptotic cells (46–55%). Moreover, both GCV and compound 1 were found to interact with breast cancer resistant protein (BCRP) more effectively than multidrug-resistant proteins (MRPs) in these cells. Since the expression of BCRP was higher in MCF-7 cells than in MDA-MB-231 cells, and the cellular uptake of GCV and compound 1 was smaller but increased in the presence of BCRP-selective inhibitor (Fumitremorgin C) in MCF-7 cells, we concluded that the improved apoptotic effects of higher MTX exposure were raised mainly from the inhibition of BCRP-mediated efflux of MTX. However, the effects of GCV and its derivatives on MTX metabolism and the quantitative expression of MTX metabolizing enzymes in various cancer cells need to be studied more thoroughly in the future.     

Low Voltage Digitally Controlled CMOS Current Conveyor

In this paper, a digitally controlled current conveyo(DCCC) is presented. The proposed DCCC is based on rail-to-rail folded cascode implementation with a current division network (CDN). The CDN is used to provide control on the current gain of the DCCC. The CDN uses a novel current division technique based on differential pairs. The proposed DCCC can operate from ±1.5 V supply voltages. Applications of the proposed DCCC such as variable gain amplifiers (VGA) and digitally tunedfilters have been investigated. PSpice simulations based on the AMI 1.2 µm N-well level 3 parameters are in agreement with the presented work.     

Economic dispatch using particle swarm optimization with bacterial foraging effect

This paper presents a novel modified particle swarm optimization (MPSO), which includes advantages of bacterial foraging (BF) and PSO for constrained dynamic economic dispatch (ED) problem. The proposed modified PSO consists of problem dependent four promising values in velocity vector to incorporate repellent advantage of bacterial foraging in PSO for the complex dynamic ED problem. It reliably and accurately tracks a continuously changing solution of the complex cost functions. As there is no differentiation operation in this method, all cost functions can easily be handled. The modified PSO has better balance between local and global search abilities and it can avoid local minima quickly. Finally, a benchmark data set and existing methods are used to show the effectiveness of the proposed method.     

Structural Characteristics of Antibacterial Bioresorbable Phosphate Glass

Neutron diffraction with isotopic substitution has been used to probe the local environment of silver in a melt‐quench derived bioresorbable phosphate glass. Samples enriched with ¹⁰⁷Ag and ¹⁰⁹Ag were prepared and neutron diffraction data collected. A first‐order difference was taken between the data sets to give detailed information about the silver environment in the glass matrix. The measured Ag‐O correlation has three components in the first coordination shell at 2.28 Å, 2.51 Å, and 2.58 Å with coordination numbers of 2.1, 2.7, and 1.1, respectively, consistent with silver occupying a distorted octahedral environment. These results have been correlated with those from Ag K‐edge X‐ray absorption near‐edge spectroscopy measurements. The results suggest that the addition of silver to the (CaO)_0.3(Na₂O)_0.2(P₂O₅)_0.5 system has a significant effect on the host phosphate network, with shorter and more branched chains replacing the long chains and rings normally associated with the metaphosphate composition.     

Cooperative transmission protocol with full diversity and iterative detection

The authors propose a three-node full diversity cooperative protocol, which allows the retransmission of all symbols. By allowing multiple nodes to transmit simultaneously, relaying transmission only consumes limited bandwidth resource. To facilitate the performance analysis of the proposed cooperative protocol, the lower and upper bounds of the outage probability are first developed, and then the high signal-to-noise ratio behaviour is studied. Our analytical results show that the proposed strategy can achieve full diversity. To achieve the performance gain promised by the cooperative diversity, at the relays decode-and-forward strategy is adopted and an iterative soft-interference-cancellation minimum mean-squared error equaliser is developed. The simulation results compare the bit-error-rate performance of the proposed protocol with the non-cooperative scheme and the scheme presented by Azarian et al. (2005).     

A High Bandwidth Power Scalable Sub-Sampling 10-Bit Pipelined ADC With Embedded Sample and Hold

A pipelined ADC architecture for use in sub-sampled systems which is power scalable in relation to its down sampled bandwidth is presented. The ADC uses a technique to eliminate the front-end sample hold, thereby reducing power consumption. The technique allows for a power savings of 20% compared to a previous design. A method to improve the settling behavior of rapid power-on opamps is also presented. Measured results in a 1.8 V 0.18 CMOS process verify the removal of the front-end sample and hold does not cause gross MSB errors for input frequencies higher than 267 MHz. With 50 MS/s, for the SNDR is 51.5 dB, and with 4.55 MS/s for the SNDR is 52.2 dB.     

Angiotensin I-converting enzyme (ACE) inhibitory activities of sardinelle (Sardinella aurita) by-products protein hydrolysates obtained by treatment with microbial and visceral fish serine proteases

The angiotensin I-converting enzyme (ACE) inhibitory activities of protein hydrolysates prepared from heads and viscera of sardinelle (Sardinella aurita) by treatment with various proteases were investigated. Protein hydrolysates were obtained by treatment with Alcalase^®, chymotrypsin, crude enzyme preparations from Bacillus licheniformis NH1 and Aspergillus clavatus ES1, and crude enzyme extract from sardine (Sardina pilchardus) viscera. All hydrolysates exhibited inhibitory activity towards ACE. The alkaline protease extract from the viscera of sardine produced hydrolysate with the highest ACE inhibitory activity (63.2 ± 1.5% at 2 mg/ml). Further, the degrees of hydrolysis and the inhibitory activities of ACE increased with increasing proteolysis time. The protein hydrolysate generated with alkaline proteases from the viscera of sardine was then fractionated by size exclusion chromatography on a Sephadex G-25 into eight major fractions (P₁–P₈). Biological functions of all fractions were assayed, and P₄ was found to display a high ACE inhibitory activity. The IC₅₀ values for ACE inhibitory activities of sardinelle by-products protein hydrolysates and fraction P₄ were 1.2 ± 0.09 and 0.81 ± 0.013 mg/ml, respectively. Further, P₄ showed resistance to in vitro digestion by gastrointestinal proteases. The amino acid analysis by GC/MS showed that P₄ was rich in phenylalanine, arginine, glycine, leucine, methionine, histidine and tyrosine. The added-value of sardinelle by-products may be improved by enzymatic treatment with visceral serine proteases from sardine.