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41.
Since 1950s the techniques of Operations Research (OR) and Optimization have been utilized to increase the efficiency of the production systems. With the widespread use of computers, it has even become easier to deal with industrial problems. However the complexity of the problems still reveals the difficulty in providing solutions. The use of artificial intelligence (AI) seems to attract the attention of the researcher to overcome to the difficulties. This has already been realized with several successful applications. In this study, the use of AI and OR techniques is compared using fuzzy logic. The progress of manufacturing systems, characteristics of production processes, system managements and system behavior are taken into account. The study is focussed on only discrete manufacturing.  相似文献   
42.
Galectins are ten family members of carbohydrate-binding proteins with a high affinity for β galactose-containing oligosaccharides. Galectin-1 (Gal-1) is the first protein discovered in the family, expressed in many sites under normal and pathological conditions. In the first part of the review article, we described recent advances in the Gal-1 modulatory role on wound healing, by focusing on the different phases triggered by Gal-1, such as inflammation, proliferation, tissue repair and re-epithelialization. On the contrary, Gal-1 persistent over-expression enhances angiogenesis and extracellular matrix (ECM) production via PI3K/Akt pathway activation and leads to keloid tissue. Therefore, the targeted Gal-1 modulation should be considered a method of choice to treat wound healing and avoid keloid formation. In the second part of the review article, we discuss studies clarifying the role of Gal-1 in the pathogenesis of proliferative diabetic retinopathy, liver, renal, pancreatic and pulmonary fibrosis. This evidence suggests that Gal-1 may become a biomarker for the diagnosis and prognosis of tissue fibrosis and a promising molecular target for the development of new and original therapeutic tools to treat fibrosis in different chronic diseases.  相似文献   
43.
The paper reports the first study on hierarchical assemblies (nanofibrillar micelles confined within semi-cylindrical shells) with silsesquioxane and quaternary ammonium units obtained through polymer blending intended for antimicrobial/antifungal stone coatings. The formation of hierarchical structures on solid surfaces is due to the multiple intermolecular ionic interactions, intermolecular Van der Waals and hydrophobic interactions acting among the component molecules. Their antimicrobial/antifungal properties toward the Gram-negative bacteria, Escherichia coli, Gram-positive bacteria, Staphylococcus aureus, and Candida albicans fungus were determined in aqueous solution and were found to be strongly dependent of the topographical features of the coating.  相似文献   
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In this study, a new classification algorithm in which only the selected pixels have been attempted to be classified (selected pixels classification: SPC) has been introduced and compared with the well known supervised classification methods such as maximum likelihood, minimum distance, nearest neighbour and condensed nearest neighbour. To examine the algorithm, Landsat Thematic Mapper (TM) data have been used to classify the crop cover in the selected region. It is clearly demonstrated that the SPC method has the higher accuracy with comparable CPU times.  相似文献   
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The central composite design with a quadratic model was used to investigate the effect of temperature (20–40 °C) and transmembrane pressure (TMP) (100–300 kPa) as well as pretreatment with gelatin and bentonite (0:0–300:1500 mg L?1) on permeate flux and fouling resistance during ultrafiltration of apple juice. The changes in some physicochemical properties were also investigated. Pretreatment of apple juice with gelatin and bentonite and an increase in the temperature and TMP significantly improved the permeate flux. In general, physicochemical properties of apple juice other than polyphenolics were not affected by the applied parameters. Using 150 mg L?1 of gelatin and 750 mg L?1 of bentonite for fining significantly reduced the total phenolic content and so did the fouling resistance. Fouling resistance also decreased with increasing temperature, and increasing pressure increased the fouling resistance.  相似文献   
48.
Academic effectiveness of universities is measured with the number of publications and citations. However, accessing all the publications of a university reveals a challenge related to the mistakes and standardization problems in citation indexes. The main aim of this study is to seek a solution for the unstandardized addresses and publication loss of universities with regard to this problem. To achieve this, all Turkey-addressed publications published between 1928 and 2009 were analyzed and evaluated deeply. The results show that the main mistakes are based on character or spelling, indexing and translation errors. Mentioned errors effect international visibility of universities negatively, make bibliometric studies based on affiliations unreliable and reveal incorrect university rankings. To inhibit these negative effects, an algorithm was created with finite state technique by using Nooj Transducer. Frequently used 47 different affiliation variations for Hacettepe University apart from “Hacettepe Univ” and “Univ Hacettepe” were determined by the help of finite state grammar graphs. In conclusion, this study presents some reasons of the inconsistencies for university rankings. It is suggested that, mistakes and standardization issues should be considered by librarians, authors, editors, policy makers and managers to be able to solve these problems.  相似文献   
49.
This study evaluated the current crushed rock aggregate resources and defined the suitability of potential crushed rock aggregate resource areas in the north of Kocaeli Province by using the geographical information system (GIS). Evaluation of the current aggregate market showed that almost 80 % of the total annual production (14.35 million tonnes) is supplied by the quarries located in Gebze and 20 % of the total annual production (3.65 million tonnes) is supplied by the quarries located in Hereke. The commercial crushed rock aggregate is totally supplied from the limestone and dolomite type carbonate rocks in the northern Kocaeli region. Defining the suitability of potential crushed rock aggregate resource areas was achieved by using GIS methods. First, an aggregate bedrock potential map was developed by using the geological map of the area and categorized as high, moderate and low bedrock potential areas. The high potential areas, which comprised almost 25 % of the northern Kocaeli region, contain carbonate rocks with varying physical, chemical and engineering properties. Secondly, the suitability of the bedrock potential areas was checked by considering the land-use, distance to the county centres and distance to major roads and highways layers in the weighted overlay function of the GIS. The resulting final map contained not suitable, low suitability and suitable areas for crushed rock aggregate. The suitable areas were grouped into three zones according to their geographic distributions. Further, the most promising crushed rock aggregate areas were defined based on the previous field work and surveys in the suitable areas.  相似文献   
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