In this paper, we present an optimisation model for the energy-efficient planning of future wireless networks. By applying robust optimisation, we extend this model to a robust formulation which considers demand uncertainties. The computability of the resulting model is moderate. Hence, we apply three different cutting plane approaches for an improvement. Furthermore, an extensive case study is performed to examine the price of robustness, to compare the robust solution to conventional planning, and to explore the performance of the cutting planes. 相似文献
We describe a distributed high-performance compute server that has been implemented for running compute-intensive applications on a mixture of HPC systems interconnected by Inter-and Intranet. With a practical industrial background, our work focusses on high availability, efficient job load balancing, security, and the easy integration of HPC computing into the daily work-flow at pharmaceutical companies.
The work was done in the course of the ESPRIT project P
A Distributed Pharmaceutical Application Server The client software is implemented in Java. All results are displayed in a web browser and can be forwarded to the next stage of applications used in the drug design cycle. The server software handles the job load balancing between the participating HPC nodes and is capable of managing multi-site applications.
Our environment currently supports four key applications that are used in rational drug design and drug target identification. They range from the automatic functional annotation of protein sequences to three-dimensional protein structure prediction tools and protein comparison applications. 相似文献
We show how to use the reciprocity between electroluminescence and solar cell quantum efficiency for the simulation and interpretation of electroluminescence images. The analysis of the spectral properties of the electroluminescence images obtained by using different short- and long-pass filters yields information about surface recombination velocity, bulk diffusion length and reflection of the back side in flat and textured solar cells. 相似文献
The different mammalian sphingomyelinases are involved in cell regulation, apoptosis and inflammatory events. Recent reports suggest pharmacological potential especially for inhibitors of the acid sphingomyelinase. Phosphatidyl inositol‐3,5bisphosphate (PtdIns3,5P2) is the most potent selective acid sphingomyelinase inhibitor known to date. In the present study, we synthesized analogues of PtdIns3,5P2 for initial structure–activity‐relationship (SAR) studies. We identified an inhibitor that is easy to synthesize, that has superior chemical and biophysical properties when compared to PtdIns3,5P2 and that should be stable against virtually all phospholipases. Last but not least, the new inhibitor partially protected cells from dexamethasone‐induced cell death.相似文献