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JL Van Laethem M Cremer MO Peny M Delhaye J Devière 《Canadian Metallurgical Quarterly》1998,43(6):747-751
Microcapsules are used for the formulation of drug controlled release and drug targeting dosage forms. Encapsulated hydrophobic drugs are often applied as their solutions in plant oils. The uptake of the oils in the complex coacervate microcapsules can be improved by the addition of surfactants. In this study, soybean, olive and peanut oils were chosen as the representatives of plant oils. The well characterized complex coacervation of gelatin and acacia has been used to produce the microcapsules. The amount of encapsulated oil has been determined gravimetrically. The encapsulation of the oils was high (75-80%). When the surfactants with HLB values from 1.8 to 6.7 were used, the amount of encapsulated oil was high (65-85%). A significant decrease of the oil content in the microcapsules was found when Tween 61 with HLB = 9.6 had been added into the mixture. No oil was found inside the microcapsules from the coacervate emulsion mixture containing Tween 81 (HLB = 10) and Tween 80 (HLB = 15), respectively. The results of the experiment confirm the dependence of hydrophobic substance encapsulation on the HLB published recently for Squalan. 相似文献
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Reviews the book, Psychologie de la famille by Monique V. G. Morval (1985). Morval presents a book with two views: the first looks at the axis of the family in light of systemic approaches and the second centers on the cycle of family life. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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Interventions for a variety of emotional and behavioral problems are commonly delivered in the context of treatment groups, with many using rolling admission to sustain membership (i.e., admission, dropout, and discharge from group are perpetual and ongoing). The authors present an overview of the analytic challenges inherent in rolling group data and outline commonly used (but flawed) analytic and design approaches to addressing (or sidestepping) these issues. Moreover, the authors propose use of latent class pattern mixture models (LCPMMs) as a statistically and conceptually defensible approach for modeling treatment data from rolling groups. The LCPMM approach is illustrated with rolling group data from a group-based alcoholism pilot treatment trial (N = 128). Different inferences were made with regard to treatment efficacy under LCPMM vs. the commonly used standard group-clustered latent growth model (LGM); coupled with other preliminary findings in this area, inferences from LGMs may be overly liberal when applied to data from rolling groups. Continued work on data analytic difficulties in groups with membership turnover is critical for furthering the ecological validity of research on behavioral treatments. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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FilippoDiGiovanni GnetanoBazzano AntonioGrimaldi 《今日电子》2003,(3):40-41
功率转换器的功率密度越来越高,发热问题越来越严重,这种功率转换器的设计对现代大功率半导体技术提出了新的挑战;因而,热问题的优化设计和核实变得比大功率器件的电模型更加重要,本文提出一种新的PSPICE模型,可以利用它计算MOSFET芯片在瞬变过程中的温度。其中的热阻可以从制造商提供的产品使用说明书得到。本文介绍的模型提供发热和电气参数之间的动态关系。它建立了与许可的热环境的关系,例如,栅极驱动电路、负载、以及散热器的分析与优化设计。利用这个模型可以改善散热器的设计。由于决定功率损耗的参数是分布在一定范围内,受生产制造的影响很大,因而散热器的设计往往由于无法预先知道功率损耗而无法进行。 相似文献
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Luiz Antonio Alcântara Pereira Miguel Hiroo Hirata Nelson Manzanares Filho 《Journal of Wind Engineering & Industrial Aerodynamics》2004,92(6):477-491
Two-dimensional, unsteady flow around bodies of complex geometry (or multiple bodies) at high Reynolds number is simulated using the vortex method. This method is modified to take into account the sub-grid scale phenomena through a second order velocity structure function model adapted to the Lagrangian scheme. The dynamics of the body wake is computed using the convection-diffusion splitting algorithm; the convection process is carried out with a Lagrangian Adams-Bashforth time-marching scheme and the diffusion process is simulated using the random walk method. The pressure distribution is obtained using an integral equation derived from the pressure Poisson equation, which was first developed for a single body. Results for the numerical simulation around a linear cascade of airfoils are presented. As the flow is periodic in the y direction, the discrete vortex shedding need only be considered for a reference airfoil. The flow characteristics around the NACA 65-410 series airfoils are calculated and comparisons are made with results available in the literature. 相似文献
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Mazzocco Michèle M. M.; Freund Lisa S.; Baumgardner Thomas L.; Forman Lisa; Reiss Allan L. 《Canadian Metallurgical Quarterly》1995,9(4):470
An extensive evaluation was conducted with 16-yr-old monozygotic twins concordant for the fragile X full mutation but discordant for mental retardation. The clearly affected twin had an IQ score of 47; 77% of her neuropsychological z scores were at least 2 SDs below average. Her sister had an IQ score of 105 and average neuropsychological performance. However, each girl demonstrated relative verbal strengths and visual-spatial weaknesses. Their parents rated each girl as having significant problems with attention, conduct, anxiety-withdrawal, and hyperactivity. The girls did not rate themselves as having significant anxiety. These findings are consistent with group data on females with fragile X and demonstrate the wide range of effects associated with the fragile X full mutation. This case report implicates the importance of a psychosocial phenotype of fragile X independent of cognitive ability level. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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Loranger Michel; Pépin Michel; Gignac Guy; Benoit Geneviève 《Canadian Metallurgical Quarterly》1995,36(1):59
Presents results of 3 studies on the psychometric properties of the LP-ABC (M. Loranger and M. Pépin, 1993), a French-language instrument for assessing general functioning in adults with mental retardation. The studies involved a total of 299 male and female Canadian adults with mental retardation. Results confirm the internal consistency, construct validity, criterion validity, discriminant validity, interrater reliability, and test–retest reliability of the LP-ABC. (English abstract) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献