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71.
Murat Güney Ayse Tulin Oz Ebru Kafkas 《Journal of the science of food and agriculture》2015,95(6):1268-1273
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73.
B. Ramezanzadeh S. Y. Arman M. Mehdipour 《Journal of Coatings Technology and Research》2014,11(5):727-737
The effects of lamellar aluminum (Al) and micaceous iron oxide (MIO) pigments on the anticorrosion properties of an epoxy zinc-rich coating were studied. To this end, the epoxy zinc-rich coatings containing 70% w/w spherical Zn particles, 60% w/w Zn + 10% w/w MIO, and 60% w/w Zn + 10% w/w Al were prepared. The electrochemical noise (ECN), potentiostatic polarization technique, and salt spray test were employed in order to investigate the anticorrosion performances of the zinc-rich coatings. The zinc-rich coatings morphologies were studied by scanning electron microscope (SEM) before and after the salt spray test. The open-circuit potential values were also measured at different immersion times. Results showed that MIO particles could enhance the cathodic protection duration of the zinc-rich coating by enhancing its barrier properties and reducing the zinc particles oxidation rate. It was also shown that Al particles reduced zinc-rich coating sacrificial behavior at short immersion times and increased it at long immersion times. Unlike MIO particles, Al particles behaved both as barrier and sacrificial pigment. 相似文献
74.
Ayse Cagil Kandemir;Fatma Donmez;Hatice Kaplan Can; 《Polymer Composites》2024,45(3):2352-2366
This study focuses on achieving mechanical enhancements in biocompatible organic coatings. A solvent-based method is employed to produce biocompatible nanocomposites using polyvinylpyrrolidone (PVP) and bentonite nanoclays (BNT) as constituents to achieve this objective. Subsequently, the nanocomposites are spin-coated onto a glass substrate, resulting in smooth and defect-free films with a thickness of 5 μm. Through instrumented-indentation testing, it is observed that BNT reinforcement leads to significant improvements in mechanical properties. Specifically, the addition of 0.5, 1, and 5 wt% of BNT in PVP results in enhancements of 105%, 77%, and 430% in elastic modulus, respectively, while hardness is improved by 166%, 211%, and 448%, respectively. The considerable improvements in the composite modulus cannot be adequately explained by assuming perfect adhesion between the constituents of the composite (as suggested by the Halpin–Tsai model) or by considering the contributions from the interface/network of silicate layers (as proposed by the Modified Halpin–Tsai model). Instead, the significant enhancements in hardness and modulus values are primarily attributed to a notable increase in the BNT volume fraction, ranging from 4 to 9 times, occurring under the Berkovich tip due to the aggregated silicate layers. The findings highlight the role of aggregated silicate layers in enhancing both hardness and modulus and contribute to the development of advanced biocompatible coatings with improved mechanical properties. 相似文献
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76.
Yevgeniy Kim Sanzhar Nurakhayev Ayan Nurkesh Zharylkasyn Zharkinbekov Arman Saparov 《International journal of molecular sciences》2021,22(5)
Cardiovascular disease is the leading cause of mortality and morbidity around the globe, creating a substantial socio-economic burden as a result. Myocardial infarction is a significant contributor to the detrimental impact of cardiovascular disease. The death of cardiomyocytes following myocardial infarction causes an immune response which leads to further destruction of tissue, and subsequently, results in the formation of non-contractile scar tissue. Macrophages have been recognized as important regulators and participants of inflammation and fibrosis following myocardial infarction. Macrophages are generally classified into two distinct groups, namely, classically activated, or M1 macrophages, and alternatively activated, or M2 macrophages. The phenotypic profile of cardiac macrophages, however, is much more diverse and should not be reduced to these two subsets. In this review, we describe the phenotypes and functions of macrophages which are present in the healthy, as well as the infarcted heart, and analyze them with respect to M1 and M2 polarization states. Furthermore, we discuss therapeutic strategies which utilize macrophage polarization towards an anti-inflammatory or reparative phenotype for the treatment of myocardial infarction. 相似文献
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Avnish Verma Ayse Orme Merve Vytautas Reme&#x;kevi
ius Pola Sobiecka Luke Taylor Scott Lawton Ben P Jones Elena Polycarpou Jason Bennett Brian Rooney 《International journal of molecular sciences》2021,22(5)
Cocaine is one of the most widely abused illicit drugs worldwide and has long been recognised as an agent of cardiac dysfunction in numerous cases of drug overdose. Cocaine has previously been shown to up-regulate cytoskeletal rearrangements and morphological changes in numerous tissues; however, previous literature observes such changes primarily in clinical case reports and addiction studies. An investigation into the fundamental cytoskeletal parameters of migration, adhesion and proliferation were studied to determine the cytoskeletal and cytotoxic basis of cocaine in cardiac cells. Treatment of cardiac myocytes with cocaine increased cell migration and adhesion (p < 0.05), with no effect on cell proliferation, except with higher doses eliciting (1–10 μg/mL) its diminution and increase in cell death. Cocaine downregulated phosphorylation of cofilin, decreased expression of adhesion modulators (integrin-β3) and increased expression of ezirin within three hours of 1 μg/mL treatments. These functional responses were associated with changes in cellular morphology, including alterations in membrane stability and a stellate-like phenotype with less compaction between cells. Higher dose treatments of cocaine (5–10 μg/mL) were associated with significant cardiomyocyte cell death (p < 0.05) and loss of cellular architecture. These results highlight the importance of cocaine in mediating cardiomyocyte function and cytotoxicity associated with the possible loss of intercellular contacts required to maintain normal cell viability, with implications for cardiotoxicity relating to hypertrophy and fibrogenesis. 相似文献
80.
Haruna Yamasawa Tomohiro Kobayashi Toshio Yamanaka Narae Choi Mathias Cehlin Arman Ameen 《JAPAN ARCHITECTURAL REVIEW》2021,4(2):403-416
This study aims to acquire an understanding of the fundamental feature of IJV and DV under heating operation. Full-scale experiments were conducted under these two different systems and supply air conditions along with temperature distribution and ventilation effectiveness. A wall surface of the test room was cooled as a heating load, and heating elements simulating occupants were located as internal heat load and contaminant emission source. Three cases of supply temperature were tested and the flow rate was also varied correspondingly. The position of the supply terminal was also changed to see its effect on heating performance, that is, mounted on the interior/exterior wall. For DV, the temperature/contaminant distribution differed significantly depending on the supply conditions, while that of IJV remained almost the same as a perfect mixing condition. Generally, IJV can achieve better temperature distribution compared to DV; however, the ventilation effectiveness of DV was superior to that of IJV with large supply flow rate. The correlation between the Archimedes number based on supply conditions and indices expressing local temperature and ventilation effectiveness is obtained. For IJV, the position of the terminal was found to have a larger impact on air distribution than the supply flow rate, while the opposite feature was obtained for DV. 相似文献